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One of the goals of a country is to prosper its people including people with disabilities. The welfare of persons with disabilities can be achieved through increased independence, the educational process, and patterns of care for people with disabilities. The education process and the burden of care to realize the independence of persons with disabilities are influenced by the level of disability, family economy, family environment, school environment, and community environment. This study aims to 1) analyze the level of disability, family economy, family environment, school environment, and community environment towards the burden of childcare; 2) analyze the level of disability, family economy, family environment, school environment, community environment, and the burden of child care for children's education; and 3) analyze the level of disability, family economics, family environment, school environment, community environment, the burden of care, and education of children towards the independence of persons with disabilities; 4) analyze whether the burden of care mediates the effect of variable levels of disability, family economy, family environment, school environment, community environment on the education of children with disabilities; and 5) analyze whether the education of children with disabilities mediates the effects of variable levels of disability, family economy, family environment, school environment, community environment on the independence of persons with disabilities in the Province of Bali. This study was designed using quantitative methods with 177 respondents with disabilities taken by probability sampling with proportionate stratified random sampling techniques. The analytical model used is Partial Least Square (PLS) with Structural Equation Modeling. The results showed that: 1) variables of the level of disability, family economy, family environment, and school environment directly had a positive and significant effect on the burden of caregiving and only the community environment had a direct but not significant effect on the burden of care; 2) variables of the level of disability, family economy, family environment, school environment, and community environment directly have a positive and significant effect on the education of children with disabilities and the independence of persons with disabilities; 3) the burden of care mediates the influence of the level of disability, family economy, family environment, and school environment significantly on the education of children with disabilities. While the influence of the community environment on the education of children with disabilities through the burden of caregiving as a mediating variable has no significant effect; 4) education of children with disabilities mediates the influence of the level of disability, family economy, family environment, school environment, and community environment significantly on the independence of persons with disabilities in the province of Bali. Based on the results of this study, it is hoped that the government, NGOs and social organizations to encourage increased access and quality of education for children with disabilities, skills training and empowerment of persons with disabilities to foster independence and fulfill the rights of persons with disabilities.

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