1. [Features of neurotransmitter pool in cerebrospinal fluid of patients with epilepsy].
- Author
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Raevskiĭ KS, Avakian GN, Kudrin VS, Nesterova SI, and Gusev EI
- Subjects
- Adult, Aspartic Acid cerebrospinal fluid, Brain metabolism, Brain physiopathology, Epilepsy physiopathology, Female, Glutamic Acid cerebrospinal fluid, Glycine cerebrospinal fluid, Humans, Male, Middle Aged, Severity of Illness Index, Taurine cerebrospinal fluid, gamma-Aminobutyric Acid cerebrospinal fluid, Epilepsy cerebrospinal fluid, Epilepsy diagnosis, Neurotransmitter Agents cerebrospinal fluid
- Abstract
The paper deals with the state of neurotransmitter pool in cerebrospinal fluid of epileptic patients. There were significant peculiarities of the dynamics of both excitatory (glutamate, aspartate) and inhibitory (GABA, glycine, taurine) neurotransmitters in respect of the severity of the pathologic process, frequency and type of convulsive seizures. The correlation found between a degree of the disease severity and a level of glutamate in cerebrospinal fluid after the seizures and between them could be a criterion for the prognosis of epilepsy.
- Published
- 2001