Search

This publication is the Russian translation of the Plain Language Summary (PLS) of the Cochrane Systematic Review: Crighton GL, Estcourt LJ, Wood EM, Trivella M, Doree C, Stanworth SJ. A therapeutic-only versus prophylactic platelet transfusion strategy for preventing bleeding in patients with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation. Cochrane Database of Systematic Reviews 2015, Issue 9. Art. No.: CD010981. DOI: 10.1002/14651858.CD010981.pub2

Objective: The aim of the study is the increasing the efficiency and improving the quality of dental surgical care for patients with tumor diseases of the blood system., Material and Methods: For the period from 2020 to 2022 The authors examined and treated 15 patients with tumor diseases of the blood system who were hospitalized at the National Medical Research Center for Hematology of the Ministry of Health of the Russian Federation. Of these, 11 provided dental surgical benefit. There were 5 men (33%), women - 10 (67%). The mean age of the patients was 52 years. A total of 12 surgical operations were performed: biopsies - 5; opening of the infiltrate - 3; imposition of secondary sutures - 1; bougienage of the salivary gland ducts - 1, removal of the salivary gland -1 and amputation of the tooth root - 1. Four patients underwent conservative treatment., Results: The use of methods of local hemostasis made it possible to minimize the number of hemorrhagic complications. Thus, the development of external bleeding from the postoperative wound was observed in 1 (20%) (out of 5) patients in the group of acute leukemia. Hematoma was diagnosed in 2 patients. The sutures were removed on the 12th day. Finally, the wounds were epithelialized by an average of 17 days., Conclusion: The authors believe that the most common surgical intervention in patients with tumorous blood diseases is a biopsy, which should be performed with partial resection of the tissue surrounding the tumor. In the course of dental interventions, hematological patients may develop complications caused by suppression of immunity and fatal bleeding.

Sensitivities and specificities of four commercial enzyme immunoassay test systems manufactured by Ortho (USA), Abbott (USA), Organon (Netherlands), Innotest (Belgium) and of three pilot Russian diagnostic agents created at the Mazaĭ Research and Production Amalgamation (Moscow) and the D. I. Ivanovskiĭ Institute of Virology (Moscow) and Pasteur Institute (St. Petersburg) for detection of antibody to hepatitis C have been compared. A high incidence of hepatitis C virus infection was revealed in various Moscow populations: blood and plasma donors, inpatients, and medical staff.