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The scientific review analyzes publications that prove the positive effects of bioactive lipids on human health. It is noted that certain lipids have a prophylactic effect on the body and can inhibit the development of certain diseases. The increased speed of passage of food masses after bariatric surgery affects the completeness of lipid breakdown and absorption in the stomach and small intestine. In case of significant violations, this can cause some complications in the operated patients. The effect of bioactive lipids on the metabolism of obese patients and the possibility of including lipids in the postoperative diet were analyzed.

At present, the question of the influence of climatogeographic and meteorological factors on human health continues to be relevant and causes discussions among scientists and clinicians around the world. The aim is to study the manifestations and causes of pathological meteosensitivity in patients with arterial hypertension permanently residing in the Far North. For the period from June 2017 to March 2018, 138 patients with a confirmed diagnosis of arterial hypertension (AH) were included in the study based on generally accepted criteria (ESH/ESC, 2018), permanently living in the Far North. Men – 42 people (30.4 %), women – 96 people (69.56 %). The age of the study participants ranged from 18 to 65 years, averaging 45 ± 5.6 years. 32 people smoked (23.19 %). The condition for inclusion in the study was the presence of complaints about meteosensitivity, the manifestation of meteopathies against the background of changes in meteorological conditions, the short duration and relativity of these disorders in the same patient in the same weather conditions. The main meteorological elements that can be considered predictors of meteopathies have been determined, and the main manifestations of pathological meteosensitivity in patients with AH permanently residing in the Far North have been identified. The presence of pathological meteosensitivity should probably be considered as an additional risk factor for the development of cardiovascular events. At present, details such as the manifestation of the metabolic syndrome in patients with hypertension, the degree of hypertension and the duration of the underlying disease, changes in biochemical parameters, and their associations with meteopathies require detail.

The children’s health is one of the most sensitive indicators of the environmental condition. A clear connection of the structure of the child morbidity with the ecological characteristics of the region of residence has been registered. Thus, the general child morbidity, risk to develop the congenital anomalies, chromosomal and genetic diseases, allergic, chronic neuropsychic, oncological and many other diseases are increased in the environmentally unfriendly regions. The hardest part is to identify and isolate from the multiple factors those chemical, physical or biological agents that affect negatively the human health. It is possible to observe the close connection of the wide range of the demographic and epidemiological indicators with the environmental pollution. However, to determine this connection with the action of the certain environmental, anthropogenic factors or their combinations is rather a challenging task. The lack of a single unified, publicly available sociological, medical and environmental monitoring does not allow to assess to the full extent the medical efficiency of the environmental measures, and, therefore, to justify the preventive measures to reduce the level of the eco-dependent pathology in the children.

Aim. To provide a definition and classification of nutraceutical products and to show their significane in modern integrative medicine.Background. Nutraceuticals are foodstuffs and their components, which have a positive effect on human health, including preventive maintenance and treatment of diseases. Nutraceuticals include healthy and functional foods, as well as biologically active food additives (BAFA). Healthy foods are nutritional foodstuffs without any artificial modification. These include organic, whole, and natural foods. Alongside a high nutritional value, functional food products have a positive effect on the human body due to functional food ingredients. BAFAs are food additives that contains one or several food ingredients (vitamins, mineral substances, plant components, amino acids and others). Specialists express conflicting viewpoints concerning nutraceuticals. Some nutraceuticals, such as probiotics, have confirmed their effectiveness in clinical trials, while the beneficial properties of others require further elucidation.Conclusions. The application of nutraceuticals, as well as their combined use with pharmaceuticals, in accordance with recommendations by scientific professional associations formulated on the basis of valid research studies can lead to an improvement in the quality of the life and longevity of the population. This position forms a basis for the development of integrative medicine — a contemporary approach to the treatment of diseases.

The most important area of any biophysical research is the study of the influx and conversion of energy in biological systems - bioenergy, which ensures the vital activity of the body. Analysis of the possibilities of stabilization of the human body from the standpoint of biothermodynamics is that it allows you to more fully and correctly assess the impact not only on biologically active substances, but also on human health. Analysis of the results of experimental and theoretical sources of biothermodynamics, the authors came up with the idea of positioning biologically active additives to the entropy component, which consists in the fact that drugs or surgery are required to treat a person. to any effect (reduction of chaos, therefore, a decrease in entropy). Important for understanding the thermodynamic approach to evaluating dietary supplements is that they do not increase the entropy of the system. The authors are convinced of the need to revise the paradigm for assessing biological activity (bioeffectiveness, biocorrective properties, functional capabilities) and the substances that underlie the transition from differential quantitative characteristics to an integral qualitative assessment of the overall effectiveness of oxidative processes in the body. This pattern of thermodynamics: a quantitative sign of nutritional status; the second law of thermodynamics as a qualitative characteristic of nutritional status

This article provides a general overview of sports supplements. Particular attention is paid to the basic principles of the use of sports supplements, the article indicates what types of supplements exist today, their characteristics, composition and what result an athlete can achieve in his sports activity with the help of sports nutrition. The article introduces us to the consequences of both positive and negative side effects, how they affect the human body. In order to make sure that sports supplements do not always have a positive effect on the general human body, we conducted a study among students and after studying this problem, we made conclusions. В статье предлагается общий обзор спортивных добавок. Особое внимание уделяется основным принципам их употребления, рассмотрены существующие виды добавок, их характеристики, состав. Кроме того, исследуется, какой результат может достичь спортсмен в своей деятельности с помощью спортивного питания. Представлены как положительные, так и отрицательные побочные эффекты спортивных добавок. Описан опрос студентов на тему влияния добавок на организм человека.

В статье рассматриваются вопросы загрязнения воздуха микропластиком в крупном промышленном городе. The article deals with the issues of microplastic air pollution in a large industrial city.

Актуальность исследования данной проблемы обусловлена необходимостью разработки методов определения состояния здоровья у людей старше 60 лет после заболевания COVID-19. Ведущим методом в исследовании данной проблемы является метод «Медискрин», представляющий собой определение состояния здоровья человека при помощи измерения электрической проводимости кожи в 24 биоактивных точках тела человека по методу Накатани. В статье выявлены показатели здоровья людей старшего и пожилого возраста, которые можно использовать в качестве критериев для определения последствий заболевания COVID-19. Представленные в статье материалы позволяют организовать научные исследования по разработке мер реабилитации и восстановления населения в период пандемии., The relevance of the study of this problem is due to the need to develop methods for determining the state of health in people over 60 years of age after the disease COVID-19. The leading method in the study of this problem was the Mediskrine method, which is a method for determining the state of human health by measuring the electrical conductivity of the skin at 24 bioactive points of the human body according to the Nakatani method. The article identifies health indicators of older and elderly people that can be used as criteria for determining the consequences of the COVID-19 disease. The materials presented in the article make it possible to organize scientific research on the it possible to organize scientific research on the development of measures for the rehabilitation and recovery of the population during the pandemic., ВЕСТНИК МОСКОВСКОГО ГОРОДСКОГО ПЕДАГОГИЧЕСКОГО УНИВЕРСИТЕТА. СЕРИЯ: ЕСТЕСТВЕННЫЕ НАУКИ, Выпуск 2 (46) 2022

Одной из задач работы является оценка экономического ущерба от риска для здоровья населения в контексте факторного анализа окружающей среды. Расчет основан на предположении, что из-за негативных факторов, влияющих на окружающую среду, существует вероятность развития у населения неизлечимых заболеваний, являющихся предпосылкой преждевременной смерти. Степень экономического ущерба от риска для здоровья в Армении напрямую зависит от макроэкономических показателей, таких как ВВП, средняя заработная плата, а также показателей, определяющих эффективность здравоохранения, таких как ожидаемая срок службы участка, возраст умершего, численность трудоспособного населения., One of the tasks of the work is to assess the economic damage of the risk to the health of the population in the context of factor analysis of the environment. The calculation is based on the assumption that due to the negative factors affecting the environment, there is a possibility that the population develops incurable diseases, which are a prerequisite for premature death. The extent of economic damage to health risks in Armenia directly depends on macroeconomic indicators such as GDP, average wages, as well as indicators that determine the effectiveness of health, such as the expected site life expectancy, the age of the deceased, the number of working age population.

The paper describes the geomagnetic disturbances significance in the complex of reasons for the meteosensitivity occurrence. The age-related characteristics of the influence of changes in weather conditions (including geomagnetic fields) on health, functional state and safety of human life are considered. The emphasis is made on the important role of physical activity optimization in the meteosensitivity prevention and correction of negative consequences caused by changes in weather conditions. It is emphasized that such studies are of particular relevance in conditions of forced hypokinesia during lockdowns, used as measures to combat the spread of the Covid‑19 epidemic. Рассматриваются возрастные особенности влияния изменений погодных условий (в том числе геомагнитных полей) на здоровье, функциональное состояние и безопасность жизнедеятельности человека. Делается акцент на важную роль оптимизации двигательной активности в профилактике метеочувствительности и коррекции негативных последствий, вызванных изменениями погодных условий. Подчеркивается, что подобные исследования приобретают особую актуальность в условиях вынужденной гипокинезии в период локдаунов, используемых в качестве мер борьбы с распространением эпидемии COVID‑19.

The possibility of using tiger nut flour (chuf) in the production of wheat bread is considered. During the experiment, trial baking of bread with different dosage of tiger nut flour and wheat flour was carried out. The parameters of mixtures of tiger flour and wheat flour of the first grade in the ratios were studied 5:95; 10:90; 15:85. The research was carried out in the laboratory of the Department "technology of storage and processing of agricultural raw materials and flour public catering" of Volgograd state agrarian University. During the experiment were studied: problems at the present stage in the baking industry; geography of growth, yield and quality of tiger nut; chemical composition of tiger nut and flour derived from it; the impact of tiger nut on human health and well-being; organoleptic indicators of bread quality; physico-chemical indicators of bread quality; change in baking properties of wheat bread with the addition of tiger nut flour. As result of the study, the possibility of producing wheat bread using tiger nut flour was established, as well as the optimal dosage of tiger nut flour and wheat flour allowing to obtain bread with high organoleptic and physico-chemical parameters.

In February 2017 the World Health Organization first published the list of antibiotic-resistant «priority pathogens» — a catalogue of 12 species of bacteria that pose the greatest threat to human health. The list highlights the danger posed by Gramnegative bacteria that are resistant to multiple antibiotics. Thus, the development of new antimicrobial medicines is becoming a pressing issue. The list is an important reference point and incentive to secure and guide research and development related to new antibiotics that will help solve the issue of growing global resistance to antimicrobial medicines. The aim of the study was to determine the main regulatory approaches to planning preclinical and clinical development programmes for new antimicrobial medicines. On the basis of current requirements and recommendations in force in the Russian Federation and guidelines of the European Medicines Agency, the issues of planning antimicrobial drug development programs were considered. The autors analysed the main stages and aspects of preclinical studies of medicines for infectious diseases (specific activity in vitro and in vivo, PK-PD modeling), as well as requirements for the clinical trial stage, including the rationale for the choice of clinically relevant efficacy and safety endpoints, study design, and statistical methods.

One of the topical problems of modern medicine is the impact of microbiota on human health. The correlation between microbiome disorders and the development of diseases of the gastrointestinal tract, skin, respiratory system, obesity, autism and even depression has been established. Specialists pay most attention to the formation and maintenance of microbiota balance in children from birth, which is necessary for the preservation of their health in the future. Microbiota is studied by scientists from all over the world, which makes it possible to establish safe and effective strains of probiotic bacteria and on their basis to create a new generation of multiprobiotics. Creation of modern probiotics, their rational use and efficiency were discussed at the international symposium «Microbiotic disorders as an interdisciplinary problem of global level», held in the framework of the XVII Russian Congress «Innovative technologies in pediatrics and pediatric surgery» in October 2018. Dr. Ashton Harper (UK) and Professor Irina Zakharova shared their experience of effective dysbiosis correction with the help of modern English multiprobiotic Bak-Set.

Treatment of insomnia is an important medical and social problem due to its widespread prevalence and significant negative impact on human health. The state of chronic cerebral hyper-activation, which has cognitive, electrophysiological and metabolic manifestations, plays an important role in the development of insomnia. The sleep disorder has been proven to be a risk factor for the development of arterial hypertension, metabolic syndrome, immunodeficiency disorder and cognitive impairment. Nonmedicinal and medicinal products are used to treat insomnia. Cognitive-behavioural therapy may be effective as a psychotherapy. Non-benzodiazepine GABA-receptors agonists are most often used to treat chronic insomnia and histamine receptor blockers to treat acute insomnia among the other drugs of this group.

В данной статье исследуются химические показатели, характеризующие содержание в отходах сокового производства черной смородины и черники, рассматривается влияние антиоксидантных веществ, на организм человека. Целью статьи является изучение химического состава и антиоксидантной активности свежезамороженных ягод черники и черной смородины, свежевыжатого сока черники и черной смородины, сырых и сушенных выжимок исследуемых ягод, прошедших кратковременную тепловую обработку, водных вытяжек и концентрированных водных вытяжек данных ягод, а также последующее сравнение значений всех данных. Мы демонстрируем методы определения общего содержания фенольных соединений, общего содержания флавоноидов, общего содержания антоцианов, FRAP метод (метод определения антирадикальной активности), метод оценки антиоксидантных свойств с использованием модельной системы линолевой кислоты, а также метод определения восстанавливающей силы. Исследования проводились на водно-спиртовых экстрактах, полученных при атмосферном давлении и температуре 37°С. Результаты исследования показывают, что высушенные выжимки ягод черники, по сравнению с прочими исследуемыми объектами как черники, так и черной смородины, имеют максимальные значения всех химических характеристик, что является оптимальным вариантом для здоровья человека., This article examines the chemical characteristics contained in the waste of juice production of black currants and blueberries. the influence of antioxidant substances on the human body is considered. The aim of the article is to study the chemical composition and antioxidant activity of freshly frozen blueberries and black currants, fresh juice of blueberries and black currants, raw and dried pomace of the studied berries, which underwent short-term heat treatment, water extracts and concentrated water extracts of these berries, as well as the subsequent comparison of the values of all data. We demonstrate methods for determining the total content of phenolic compounds, total flavonoids, total anthocyanins, FRAP method (method for determining antiradical activity), a method for evaluating antioxidant properties using a model system of linoleic acid, as well as a method for determining the restoring force. Studies were carried out on water-alcohol extracts obtained at atmospheric pressure and temperature of 37°C. The results of the study show that dried blueberries, compared with other objects studied as blueberries and blackcurrants, have the maximum values of all chemical characteristics, which is the best option for human health.

10995/27938 Общее потребление газводы в мире постоянно растет и вызывает опасение у диетологов, врачей, отмечающих закономерности между развитием целого ряда опасных хронических заболеваний и пристрастием к сладким напиткам. В работе исследовано значение состава употребляемых сладких газированных напитков для сохранения здоровья человека, параметры безопасного приема, а также проведён анализ результатов анонимного анкетирования студентов медицинского колледжа по некоторым медико-социальным аспектам употребления газированных напитков. Мыопределили наличие сахара в сладких газированных напитках и глюкозы крови. Заключение, рекомендации и информационно образовательные материалы составлены по проблемным вопросам темы. Theworld’s growing consumption of soda is constantly increasing and is causing concern among nutritionists, physicians, who note the patterns between the development of a number of dangerous chronic diseases and addiction to sugary drinks. We’ve had to eat sugar in sugary fizzy drinks and blood glucose. Recommendationsand educational materials are compiled on problematic issues of the topic.

Суринамский мукоед (Oryzaephilus surinamensis Linnaeus) широко распространен по всему миру. Это один из самых опасных вредителей сельскохозяйственной и пищевой продукции, кроме того, он представляет угрозу здоровью людей. Для борьбы с суринамским мукоедом предлагается применение инсектицидных средств и ионизирующего излучения., Sawtoothed grain beetle (Oryzaephilus surinamensis Linnaeus) is widely distributed throughout the world. It is one of the dangerous pests of agricultural and food products. In addition to the harm caused to agriculture, the sawtoothed grain beetle is also dangerous for human health. As a way to fight against this pest, the use of insecticidal agents and ionizing radiation are proposed., ПЕСТ-МЕНЕДЖМЕНТ, Выпуск 3 (119) 2021, Pages 5-10

Амбарный долгоносик (Sitophilus granarius Linnaeus, 1758) – один из древнейших и очень опасных вредителей сельскохозяйственной и пищевой продукции. Кроме того, амбарный долгоносик опасен для здоровья людей. В качестве эффективного способа борьбы с этим вредителем рекомендуется применение инсектицидных средств и ионизирующего излучения., The grain weevil (Sitophilus granarius Linnaeus, 1758) is one of the oldest and most dangerous pests of agricultural and food products. In addition, grain weevil is dangerous to human health. As an effective way to control this pest, the use of insecticides and ionizing radiation recommended. Keywords: grain weevil, pests of grain stocks, allergies, infections, human health, insecticide, ionizing radiation., ПЕСТ-МЕНЕДЖМЕНТ, Выпуск 4 (116) 2021, Pages 5-11

Current climate changes have a significant impact on the human health and life quality. Negative factors of climate change threaten basic health components that human needs, such as clean air, safe drinking water, food safety, hygiene and sanitary living conditions, and can sweep away decades of progress in the field of health care protection. Strategies for climate change adaptation, directed at the GHG reduction, provide co-benefits that significantly reduce health-care expenditures.

Токсины, которые образуются в результате жизнедеятельности личинок южной амбарной огневки (Plodia interpunctella Hübner, 1813), негативно влияют на здоровье человека, вызывая аллергические проявления. Это требует активной борьбы населения с этим насекомым в домашних условиях. Однако недавно обнаруженная способность личинок (гусениц) южной амбарной огневки перерабатывать полиэтилен существенно повышает ее значение в качестве биологического способа утилизации полиэтилена., Toxins produced by the larvae of the Indian meal moth (Plodia interpunctella Hübner, 1813) have a negative impact on human health. This requires an active struggle of the population with this insect at home. However, the recently discovered ability of larvae (caterpillars) of the Indian meal moth to reprocess polyethylene significantly increases its value as a biological method of utilization of polyethylene., ПЕСТ-МЕНЕДЖМЕНТ, Выпуск 3 (115) 2020, Pages 30-33

The paper is devoted to the problem of using genetically modified organisms (GMOs). The analysis of foreign and Russian research is given. Positive and negative properties of GMOs are described. Special attention is paid to the negative effects of GMOs on human health. There is no clear answer to the question about the use of GMOs in food production. The authors focus on the need for stricter control over the production of GM products in order to ensure food security. Работа посвящена проблеме использования генетически модифицированных организмов (ГМО). Приведен анализ зарубежных и российских исследований. Описаны положительные и отрицательные свойства ГМО. Особое внимание уделяется негативным последствиям воздействия ГМО на здоровье человека. Отмечено отсутствие однозначного ответа на вопрос об использовании ГМО при производстве продуктов питания. Авторы останавливаются на необходимости более жесткого контроля за производством ГМ-продуктов в целях обеспечения продовольственной безопасности.

Данная статья посвящена проблеме загрязнения окружающей среды. Рассмотрены источники ее загрязнения, меры борьбы и защиты природной среды. Статья также призвана обратить внимание людей на глобальные проблемы окружающей среды и причины их появления. Планета Земля – наш единственный дом, а мы своими руками губим его., This article is devoted to the problem of environmental pollution. The sources of its impact, measures of control and protection of the natural environment are considered. It is also necessary to pay attention to global environmental problems and their causes. Planet Earth is our only home, we are ruining it with our own hands., Вестник Комплексного научно-исследовательского института им. Х.И. Ибрагимова РАН, Выпуск 2 (2) 2020

Современный мир сталкивается с негативными проблемами, оказывающие непосредственное влияние на жизнь и здоровье человека. Самыми распространенными проблемами являются: употребление нездоровой пищи, отсутствие экопродуктов и загрязнение окружающей среды., the Modern world is facing negative problems that have a direct impact on human life and health. The most common problems are: eating unhealthy food, lack of eco-products, and environmental pollution., Вопросы устойчивого развития общества, Выпуск 7 2020

Long standing author’s experience of healthy life style forming in organizations of common and professional education and in system of raising the level specialists’ skill is presented in the article. Generalized model contained seven functional blocks, suitable for creation of particular programmes of healthy life style in different educational groups, is proposed. Представлен многолетний опыт по формированию здорового образа жизни человека в организациях общего и профессионального образования, а также в системе повышения квалификации специалистов. Предложена обобщенная модель, состоящая из семи функциональных блоков, пригодная для построения частных программ здорового образа жизни в разных образовательных коллективах.

Представлен многолетний опыт по формированию здорового образа жизни человека в организациях общего и профессионального образования, а также в системе повышения квалификации специалистов. Предложена обобщенная модель, состоящая из семи функциональных блоков, пригодная для построения частных программ здорового образа жизни в разных образовательных коллективах Long standing author’s experience of healthy life style forming in organizations of common and professional education and in system of raising the level specialists’ skill is presented in the article. Generalized model contained seven functional blocks, suitable for creation of particular programmes of healthy life style in different educational groups, is proposed

Continuous and steady running of health status remote monitoring systems is essential not to omit episodes of acute exacerbation of chronic disease. Running time of such systems is largely determined by performance capabilities of the patient's wearable system elements. To ensure its long-term operation and efficient performance, the monitoring system must have multilayered structure with the elements realizing recording and picking off biomedical signals, signal processing and analysis, estimation of patient current condition, dynamics of the disease and its prognosis. For this purpose, it is necessary to use smart monitoring algorithms. A specific feature of such algorithms is change of the number of channels used for biomedical signal recording and processing according to the change of patient’s condition. To detect the exacerbation first symptoms by means of the patient's wearable computer, additional channels are activated for recording biomedical signals used to evaluate the expanded complex of diagnostically significant parameters of the disease and their integration when specifying the patient's condition. The system and intelligent monitoring algorithm is tested with the use of heart rate remote control and atrial fibrillation episode detection system. The testing results of the developed system and algorithm are discussed.

Dietary fibers (DF) are defined as the lignin and polysaccharide components of plants that are not digested by enzymes in the human’s digestive tract. The use of DF is recommended by physicians because of their impact on reducing the risk of diabetes, colon cancer, obesity and cardiovascular diseases. Functional products are products used to prevent and treat certain diseases. The development of functional meat products is an innovative focus area in the food industry, which has an extremely important practical value and social efficiency. The development of new generation of meat products, functional food and products enriched with functional components is associated with the rapid development of the industry of food additives and ingredients, as well as creation of new technologies and equipment in the food industry. One of the most popular trends in the development of functional products is the addition of dietary fibers. Dietary fibers are the components (amino acids, peptides and proteins, vitamins and minerals, antioxidants, oligosaccharides, sugars/alcohols, glucosides, etc.) that have been identified as potentially useful functional ingredients for human health. Harmful products or fast foods have become the cornerstone of healthy diets in modern society. Many of these harmful products contain insufficient amount of meat and minimal amount of dietary fibers. The introduction of DF in the daily diet (meat, dairy products and pastry products) can help filling the gap in the dietary fibers. DF can also be added to meat products to reduce caloric content by replacing fat, and to improve the stability and texture of meat products.

How eating gluten may be associated with various disorders of human health including neurological diseases remains a topic of discussion in the academic and civil circles. Application of gluten-free diet is of particular interest for the complex management of diseases such as autism, schizophrenia, and borderline neurological disorders including chronic fatigue syndrome, various cognitive impairments, depression, etc. The article presents a review of the studies of efficacy of gluten-free diet in patients with various neurological diseases and psychiatric disorders; the potential mechanisms of the neurotropic action of gluten are also examined.

Among the products of functional nutrition, special attention is paid to probiotic cultured milk foods. When selecting these products, it is necessary to focus on the characteristics of the probiotic strains that make up their composition: microorganisms must be live, safe to use, viable and stable when stored, and also capable of surviving in the human gastrointestinal tract. The use of probiotic cultured milk foods should have a positive effect on human health: to have a proven anti-infective effect, to have immune modulating properties, to promote the normalization of gastrointestinal motility. The above provisions must be confirmed by controlled studies.

The concept of pro- and prebiotic therapy finds both its followers and opponents. However, there is no doubt that there is a close connection between the microbiota of the various epitopes of our organism and the functioning of its individual organs and systems, as well as of the body as a whole. The accumulated amount of reliable data on the functioning of the microbiocenosis of the human organism makes it possible to see them as key points of influence on human health, not only in the treatment of existing diseases, but also in terms of primary and secondary prevention of a wide range of infectious, metabolic, immune-mediated and other diseases. In the near future, scientists would need to identify the indications, find effective probiotic strains, determine optimal one-time and daily doses, duration of the therapy, and criteria for effectiveness of the therapeutic and/or preventative measures.