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The aim of the work is to reveal the influence of psycho-physiological factors on the individual performance in a track and field sprint among highly qualified athletes with visual impairment on the example of an elite athlete. Material and methods. highly qualified athlete participated in the study, specializing in short-distance running and long jump among athletes with visual impairments in 2010 European Athletics Champion; winner of the World Paralympic Championships and the Paralympic Games for Athletes with Visual Impairment (Category T12) 2016. Psychophysiological testing athlete held close to the screen. The course of the study. The individual characteristics of the psychophysiological state and the results in the 200 m race for five months were analyzed. The results in the 200 m race were recorded at the official and unofficial competitions. A total of 36 results were analyzed. Results. Multiple linear regression models were compiled between results in a 200 m race for an elite athlete with visual impairment and psycho-physiological indicators. The selected model of multiple regression is represented by the following variables: simple visual motor response time (ms), total test time with feedback at 120 signals (s), time to reach the minimum signal exposure in a test with feedback at 30 signals (s) , the time to reach the minimum signal exposure in the test with feedback at 120 signals (s). Conclusions. The compensatory mechanisms of visual function insufficiency to maintain high speed in 200 m run as psycho-physiological functions were revealed: indicators characteristic of sprinters (simple reaction speed and mobility of the nervous system) and specific indicators (efficiency, strength of the nervous system).