1. [Royleanones in the roots of Salvia officinalis L. of domestic provenance and their antimicrobial activity].
- Author
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Masterová I, Misíková E, Sirotková L, Vaverková S, and Ubik K
- Subjects
- Anti-Bacterial Agents pharmacology, Diterpenes isolation & purification, Slovakia, Staphylococcus aureus drug effects, Abietanes, Anti-Bacterial Agents isolation & purification, Diterpenes pharmacology, Plant Extracts pharmacology
- Abstract
The reported investigation of the constituents of the petroleum ether extract of the root of Salvia officinalis L. confirmed the presence of the following diterpene quinones: 12.hydroxy-8, 12-abietadiene-11, 14-dione (royleanone), 7 alpha, 12-dihydroxy-8.12-abistadiene-11-14-dione (horminone) and 7 alpha-acetoxy-12-hydroxy-8, 12-abietadiene-11,14-dione (7-O-acetylhorminone). The compounds were identified on the basic of the interpretation of results of spectral analysis. Isolated royleanones show antimicrobial activity against gram-positive bacteria (Staphylococcus aureus). A study of abietate diterpenoids in the root of Salvia officinalis L. of Slovak provenance has been performed for the first time.
- Published
- 1996