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Ena izmed pomembnih reakcij v klik kemiji je 1,3-dipolarna cikloadicija, ki spada med periciklične reakcije. Cikloadicija se uporablja za sintezo heterocikličnih sistemov z lihim številom atomov v obroču. V uvodu diplomskega dela se bom posvetil lastnostim in sintezi azometin iminov in pirazolidin-3-onom, ki lahko služijo kot izhodne spojine za pripravo najrazličnejših heterociklov, med katerimi bom več pozornosti namenil pirazolo[1,2-a]pirazolom. Eksperimentalni del diplomskega dela vključuje sintezo azometin iminov iz pirazolidin-3-onov in 1,3-dipolarno cikloadicijo azometin iminov na terminalne alkine za sintezo pirazolo[1,2-a]pirazolov ter njihove fotokemične pretvorbe. One of the most important reactions in click chemistry is 1,3-dipolar cycloaddition, which belongs to the pericyclic reactions. Cycloaddition is used to synthesise heterocyclic systems with an odd number of atoms in the ring. In the introduction of my work, I will focus on the properties and synthesis of azomethine imines and pyrazolidin-3-ones, which can serve as starting compounds for the preparation of a variety of heterocycles, paying more attention to pyrazolo[1,2-a]pyrazoles. The experimental part of the work includes the synthesis of azomethine imines from pyrazolidin-3-ones and 1,3-dipolar cycloaddition of azomethine imines to terminal alkynes for the synthesis of pyrazolo[1,2-a]pyrazoles and their photochemical transformations.

Klik kemija je ena izmed novejših načinov organske sinteze, pri kateri se sintetizirajo nove spojine s C–X–C vezmi. Da reakcija spada med klik kemijo, morajo biti izpolnjeni določeni pogoji. Ena izmed najbolj pomembnih reakcij v klik kemiji je 1,3-dipolarna cikloadicija, ki spada med periciklične reakcije in se uporablja za sintezo heterocikličnih sistemov z lihim številom atomov v obroču. Poleg tega sem se v uvodu posvetil azometin iminom, ki so vključeni v sintezo najrazličnejših heterociklov. Zadnji del uvoda opisuje biciklične pirazolidinone. Eksperimentalni del diplomskega dela vključuje sintezo azometin iminov iz 3-pirazolidinonov in 1,3-dipolarno cikloadicijo azometin iminov na terminalne alkine za sintezo pirazolo[1,2-a]pirazolov. Click chemistry is one of the newer methods of organic synthesis, where new compounds with C–X–C bonds are synthesized. For a reaction to be defined as click chemistry, certain conditions must be met. One of the most important reactions in click chemistry is 1,3-dipolar cycloaddition, which is a pericyclic reaction and is used to synthesize heterocyclic systems with an odd number of atoms in the ring. In addition, in the introduction I focused on azomethine imines, which are involved in the synthesis of wide variety of heterocycles. The last part of the introduction describes bicyclic pyrazolidinones. The experimental part of the thesis includes the synthesis of azomethine imines from 3-pyrazolidinones and the 1,3-dipolar cycloaddition of azomethine imines to terminal alkynes for the synthesis of pyrazolo[1,2-a]pyrazoles.