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Caso clínico: Paciente epiléptico de 63 años en tratamiento con vigabatrina que refería déficit de agudeza visual. Presentaba una retinopatía tóxica con palidez papilar e importante retracción del campo visual. Tras un año de suspensión del tratamiento persistía la retracción campimétrica. Discusión: Neurólogos y oftalmólogos debemos concienciarnos del potencial efecto retinotóxico de la vigabatrina. No hay consenso en cuanto a la estrategia de screening a utilizar. Una evaluación campimétrica hasta los 60º y una tomografía óptica de coherencia (OCT) parecen ser test diagnósticos sensibles en el screening de pacientes que toman vigabatrina. Case report: We report a case of a 63-year-old patient with epilepsy treated with vigabatrin, who was seen because of diminished visual acuity. Examination showed a toxic retinopathy with optic nerve pallor and severely constricted visual fields. One year after cessation of the vigabatrin, no change in the perimetric constriction had occurred. Discussion: Ophthalmologists and neurologists need to be aware of the possibility of retinal toxicity due to the use of vigabatrin. It is still unclear as to which ophthalmogic assessment is of the most diagnostic value; however visual field examination covering the peripheral 60º and optical coherence tomography could be most useful for the screening of patients using this agent.

Gassy sediments and large, buried and actual seafloor pockmarks are identified on seismic records in the continental slope of the Gulf of Cadiz. The different acoustic responses produced by the gas in the sediment result from the local dynamic of the Mediterranean Undercurrent, which also controls the lithology of the slope sediments. The seafloor areas swept by this strong current are covered by coarse sediments with high porosity, which favours the escape of the gas, and then the development of pockmarks. Contrasting, the areas affected by weaker currents are covered by finer sediments of low porosity, and then the gas remains trapped into the sediment pores

A comprehensive data set of the seafloor relief and superficial sedimentary cover on the Ebro progradational continental slope, NW Mediterranean Sea, reveals that its Late Quaternary building results from complex interrelationships between processes ranging from channel abandonment to incision of inner minor courses, from retrogressive erosion and channel capture to levee cutting and new channel opening, from channel wall sliding to shelf-edge and channel spillover. These processes succeed ones to the others both in time and space conforming a canibalistic frame where the balance between destructive and constructive processes is finally favourable to the last. They result in the formation of the channel-levee complexes characteristic of the Ebro continental slope and base-of-slope

A peripheral depression with a sediment drift on its N flank develop N and E of Minorca Island. Both are interpreted to result from the activity of bottom currents circulating parallel to the base of the island slope since the Pliocene. Evidences of the contouriric activity are: the presence of a depression with an erosive character, a sedimentary ridge with the typical characteristics of contourite drifts, and large sediment waves. The depression has a maximum width of 5 km, and a depth of 150-200 m, whereas the contourite drift reaches up to 150 km in length, is 25 km wide, and 100 m high. The sediment waves developed on the inner flank of the contourite drift reach up to 5 km in length and 40 m in height. The genesis of all these structures is related to the circulation of the Mediterranean Deep Water ( MDW) in the area. The steep island slope, devoided of sediment and deeply gullied, is considered as the potential source area for the sediments reworked by the currents. Further seaward, the contourite deposits are in lateral continuity with the deposits of the North-Balearic Basin and the Valencia Fan

A comprehensive data set of the seafloor relief and superficial sedimentary cover on the Ebro progradational continental slope, NW Mediterranean Sea, reveals that its Late Quaternary building results from complex interrelationships between processes ranging from channel abandonment to incision of inner minor courses, from retrogressive erosion and channel capture to levee cutting and new channel opening, from channel wall sliding to shelf-edge and channel spillover. These processes succeed ones to the others both in time and space conforming a canibalistic frame where the balance between destructive and constructive processes is finally favourable to the last. They result in the formation of the channel-levee complexes characteristic of the Ebro continental slope and base-of-slope

Gassy sediments and large, buried and actual seafloor pockmarks are identified on seismic records in the continental slope of the Gulf of Cadiz. The different acoustic responses produced by the gas in the sediment result from the local dynamic of the Mediterranean Undercurrent, which also controls the lithology of the slope sediments. The seafloor areas swept by this strong current are covered by coarse sediments with high porosity, which favours the escape of the gas, and then the development of pockmarks. Contrasting, the areas affected by weaker currents are covered by finer sediments of low porosity, and then the gas remains trapped into the sediment pores

A peripheral depression with a sediment drift on its N flank develop N and E of Minorca Island. Both are interpreted to result from the activity of bottom currents circulating parallel to the base of the island slope since the Pliocene. Evidences of the contouriric activity are: the presence of a depression with an erosive character, a sedimentary ridge with the typical characteristics of contourite drifts, and large sediment waves. The depression has a maximum width of 5 km, and a depth of 150-200 m, whereas the contourite drift reaches up to 150 km in length, is 25 km wide, and 100 m high. The sediment waves developed on the inner flank of the contourite drift reach up to 5 km in length and 40 m in height. The genesis of all these structures is related to the circulation of the Mediterranean Deep Water ( MDW) in the area. The steep island slope, devoided of sediment and deeply gullied, is considered as the potential source area for the sediments reworked by the currents. Further seaward, the contourite deposits are in lateral continuity with the deposits of the North-Balearic Basin and the Valencia Fan

The GEBRA '93 (Geological Evolution of the Bransfield Basin) survey was carried out in December 1993 in the Bransfield Strait (NW Antarctic Peninsula) and adjacent areas, onboard BIO Hespérides. The geophysical data acquired allow to characterize the morphostructure, sediment cover and magnetic anomalies of the SW-NE trending Central Bransfield Basin. Some transverse shifts and tresholds, together with alongbasin volcanic alignments, complicate the morphology and seismic structure of what otherwise would have been a long, continuous axial trough opened on a crust under extension. A major submarine valley, named Gebra Valley has also been identified

The GEBRA '93 (Geological Evolution of the Bransfield Basin) survey was carried out in December 1993 in the Bransfield Strait (NW Antarctic Peninsula) and adjacent areas, onboard BIO Hespérides. The geophysical data acquired allow to characterize the morphostructure, sediment cover and magnetic anomalies of the SW-NE trending Central Bransfield Basin. Some transverse shifts and tresholds, together with alongbasin volcanic alignments, complicate the morphology and seismic structure of what otherwise would have been a long, continuous axial trough opened on a crust under extension. A major submarine valley, named Gebra Valley has also been identified