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La Decisión Andina 486 de 2000 reguló varias medidas relacionadas con la observancia y protección de los derechos de propiedad industrial. Sin embargo, dicha decisión dejó de lado la regulación de medidas relacionadas con el recaudo probatorio de elementos requeridos para acreditar una potencial infracción. El presente artículo busca exponer la forma en que la práctica colombiana ha atendido estas medidas a través del mecanismo de las pruebas extraprocesales, y llamar la atención sobre la posible necesidad de regular lo propio a través del derecho andino.

At present widespread use of models as an auxiliary system to penetrate the essence of phenomena related to all areas of cognitive and transforming activity of man, covering as diverse as human sciences fields. In the field of education use it is becoming more common as essential to transform school practice and enrich their theoretical instrument bitter day. The paper deals with the development of theoretical modeling as a scientific method to advance the process to be transformed and characterized by establishing relationships and links between the structural components that comprise it. In this regard it is proposed as an objective socialize some theoretical and methodological considerations that favor the use of modeling method in the scientific research activity of teachers.

This paper addresses the proposal of a didactic model of the dynamics of the motivation for learning of physics, which is based on the theoretical systematization of communicative interdisciplinarity as conception of Barrera (2003) and pedagogical professional pre approach Despaigne (2012) for teachers in training career mathematically Physics. The same is rooted in systemic-structural method. This educational model will be implemented in practice through a strategy of the same nature for motivation for learning physics with what can contribute to the solution of the dialectical contradiction between what is understood, cognitive self-reflection of teachers in training and given the experiences and feelings related to what you learn, invigorated by the method of disclosure teaching of science

Deals with the present situation of the process the professional librarians´ logic training, as well as, the role they play as active protagonists within the society of information and in the support to the educative change. The aim of this piece of paper is to think about the school librarian´s teaching functions ,taking into account the methodological matter, the orientation and the research-upgrading. There used methods of investigation of the empiric and theoretical level, such as: historical-logical, analysis and synthesis, induction deduction; observation, survey and interview.

Existen características que señalan o definen la inquietud de los hombres en las diferentes épocas de la historia en el campo de la cultura, así́, en la edad del renacimiento, las artes plásticas son su interés primordial y en los actuales momentos, los rápidos adelantos en los medios de comunicación, las ideologías buscando un nivel social estable que beneficie a la comunidad y el interés por el conocimiento científico de todas las esferas de la sexualidad, son los signos de los tiempos que corresponden al mundo de hoy.

Objectives: Retrospective review of 106 germ-cell testicular tumors treated in our center between 1992 and 2009., Methods: Description and analysis of several clinical-pathologic and prognostic variables and survival analysis., Results: 68% of our patients were diagnosed in the last 5 years. 54.7% presented seminoma histology. The mean age at diagnosis was 33.47 for the seminoma (S) and 27.63 for non seminoma (NS), p=0,001. The median tumoral size in mm was 45.99mm (globally). 44.3% presented elevation of at least one tumor marker; Alpha-fetoprotein (AFP) or Human chorionic gonadotropin (HCG) .29.3% in the S and 60.4% in NS; p=0.02. The percentage of patients with increased HCG in S was 29.3% and 52.1% in NS; p=0.017 and AFP was elevated in 5.2% of S and 45.8% of NS; P <0.001. Accordingly to the classification of The Royal Marsden Hospital 96.5% of S and 83.2% of NS were diagnosed in stage I-II. Using the classification of the International Germ Cell Cancer Collaborative Group (IGCCG) for patients with advanced disease, 98.2% of S and 83.2% of NS belonged to the good prognostic group. Regarding the risk factors for relapse in stage I S (Rete testis invasion (RTI) and tumoral size (TS)> 4cm) 28% of our patients presented both risk factors. 18% of stage I NS presented vascular (VI) or lymphatic invasion (LI). Following the treatment protocols in consideration with the histology, stage and risk factors, 100% of stage I S with both risk factors and 100% of NS with vascular or lymphatic invasion received adjuvant therapy. Almost all the stage II-IV S and NS received different protocols of chemotherapy. In 2.8% of stage II NS a retroperitoneal lymph node dissection was performed. Residual tumor resection was documented in eight patients with stage II-IV NS. With a median follow-up of 60 months, the event free survival (EFS) was 93.3%., Conclusions: Our study has similar characteristics compared to other studies.