1. [Prevalence of infections by hepatitis A, B, C and E viruses in two different socioeconomic groups of children from Santa Cruz, Bolivia].
- Author
-
Gandolfo GM, Ferri GM, Conti L, Antenucci A, Marrone R, Frasca AM, and Vitelli G
- Subjects
- Adolescent, Antibodies, Viral blood, Bolivia epidemiology, Child, Female, Hepatitis A epidemiology, Hepatitis A immunology, Hepatitis B epidemiology, Hepatitis B immunology, Hepatitis C epidemiology, Hepatitis C immunology, Hepatitis E epidemiology, Hepatitis E immunology, Hepatitis Viruses immunology, Hepatitis, Viral, Human immunology, Humans, Male, Prevalence, Socioeconomic Factors, Hepatitis, Viral, Human epidemiology
- Abstract
Background and Objectives: The epidemiology of hepatitis A, E, B and C was analyzed in 1,393 children living in Santa Cruz de la Sierra, Bolivia. They were distributed in two groups according to the social condition., Materials and Method: 1,393 children were selected from two different schools: one attended by children belonging to a high social class of the town (group A), and the other school attended by children belonging to the poorest social class (group B). Blood samples were drawn by a team of physicians from Rome University La Sapienza. Serum antibodies against hepatitis A, B, C and E virus, and the hepatitis B surface antigen were evaluated by immunometric methods. The significance was evaluated using the *2 test., Results: Antibodies against hepatitis A virus were detected in 82% of examined children, with a significant difference between the two groups (56.3% vs 94.8%). The incidence of anti-HBc antibodies increased with age, so the infection is acquired prevalently in adolescence with a significant difference between both groups (1.1% vs 3.8%). The same phenomenon was observed with anti-HCV antibodies (4.7% positivity only in group B). Serum antibodies against hepatitis E virus were observed in 1.7% cases., Conclusions: In Bolivia, as in other developing countries, viral hepatitis represents a serious burden for public health. Spreading of viral hepatitis can be controlled upon improving hygienic conditions and customs. Moreover, a vaccination plan against hepatitis A and B virus is necessary for the population living in endemic areas.
- Published
- 2003
- Full Text
- View/download PDF