1. Autoimmune post-herpes simplex encephalitis. A pediatric clinical case report.
- Author
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Soriano D, Mendoza M, Vélez J, Benavente H, and Grosman A
- Subjects
- Male, Humans, Child, Child, Preschool, Encephalitis, Herpes Simplex complications, Encephalitis, Herpes Simplex diagnosis, Encephalitis, Herpes Simplex drug therapy, Mental Disorders, Autoimmune Diseases
- Abstract
Herpes simplex virus (HSV) encephalitis is a common cause of severe and potentially fatal encephalitis. Autoimmune post-herpes simplex encephalitis (AIPHSE) affects a percentage of patients who developed herpes simplex encephalitis (HSE) and is characterized by the onset of new neurological/psychiatric symptoms and/or worsening of deficits acquired during the herpes infection within a predictable time frame. It is caused by a mechanism not related to HSV, but by autoimmune conditions, and is susceptible to treatment with immunomodulators. Here we describe the case of a 5-year-old boy with AIPHSE who required first- and second-line immunomodulatory treatment, with an adequate course and remission of symptoms., (Sociedad Argentina de Pediatría.)
- Published
- 2023
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