1. [Comparative study of clinical features between unilateral and bilateral orbital IgG4-related disease].
- Author
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Coloma-González I, Ceriotto A, Flores-Preciado J, Corredor-Casas S, and Salcedo-Casillas G
- Subjects
- Adrenal Cortex Hormones therapeutic use, Adult, Aged, Chronic Disease, Cross-Sectional Studies, Dacryocystitis diagnosis, Dacryocystitis drug therapy, Dacryocystitis immunology, Delayed Diagnosis, Eye Pain etiology, Female, Humans, Male, Middle Aged, Mikulicz' Disease diagnosis, Mikulicz' Disease drug therapy, Mikulicz' Disease immunology, Orbital Diseases diagnosis, Orbital Diseases drug therapy, Orbital Diseases immunology, Dacryocystitis etiology, Hypergammaglobulinemia complications, Immunoglobulin G analysis, Mikulicz' Disease etiology, Orbital Diseases etiology
- Abstract
Objective: Descriptive and comparative study of patients with orbital IgG4-related disease., Material and Methods: A review and analysis of the cases diagnosed with inflammatory orbital lesion related to IgG4 by the Ophthalmic Pathology Service in the Dr. Luis Sánchez Bulnes Hospital., Results: A total of 9 cases were found, in which 66% were women, and with a mean age of 48 years and time to diagnosis of 2 years. Unilateral involvement was observed in 56% of cases. All the females experienced pain, and there was an optimal response to corticosteroid treatment in 100% of patients who required medical treatment (one case showed spontaneous resolution). In bilateral cases (44%), only 25% were female, and none had pain as a presenting symptom. Furthermore, 25% of these patients required a combination with immunosuppressants to control inflammation., Conclusions: Clinical presentation of patients with unilateral orbital IgG4-related disease differs from those with bilateral involvement., (Copyright © 2014 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2015
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