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Objective: To evaluate the short term and 1-year follow-up functional effects of a physiotherapy programme in patients over 60 years of age with massive and irreparable Rotator Cuff (RC) tear., Methods: A total of 96 patients with massive and irreparable RC tear were prospectively recruited. All patients were treated with a 12-week physiotherapy programme. Three evaluations were performed, at the beginning, at the end of the treatment and at one year of follow-up. The Constant-Murley questionnaire was used to assess shoulder function, the DASH questionnaire for upper limb function, and the Visual Analogue Scale (VAS) for pain intensity., Results: At the end of the treatment, all the variables showed a clinically and statistically significant difference (p<.05). At one year of follow-up, the Constant-Murley showed an increase of 26.5 points (Cohen's d=1.7; 95% CI: 23.5-29.5; p<.001), DASH showed a decrease of 31.4 points (Cohen's d=2.2; 95% CI: 28.5-34.3; p<.001), and the VAS showed a decrease of 3.9cm (Cohen's d=3.6; 95% CI: 3.6-4.1; p<.001)., Conclusion: In the short term and 1-year follow-up, a physiotherapy programme showed clinically and statistically significant results in all functional variables in patients older than 60 years with massive and irreparable RC tear., (Copyright © 2021 The Author(s). Published by Elsevier España, S.L.U. All rights reserved.)

The liver is characterized by a remarkable ability to proliferate and self-renew. In the situation of mild or moderate liver damage, hepatocytes carry out regeneration. Nevertheless, when liver damage is far too much extensive and the number of residual mature hepatocytes is not enough to accomplish regeneration, or likewise when mature hepatocyte proliferation is inhibited, hepatic regeneration depends on the activation of liver stem cells that give rise to oval cells. The population of liver stem cells is scant in normal liver. It is considered that in fetal liver this population is just over 1% of the cells. For this reason, it is necessary to isolate and enrich them for their study. With this goal several models of hepatic damage that permit the isolation of oval cells af ter the induction of massive hepatic injure have been developed. Here we present a simple methodology that allows the isolation of oval cells from rat fetal liver without prior induction of liver damage. The use of oval cell 2 (OC2) and oval cell 3 (OC3) antigens as molecular markers allowed the highly precise characterization of this cell population. Furthermore, the in vitro culture in presence of HGF yielded a substantial enrichment of the oval cell population.

Spontaneous rupture of liver during pregnancy is associated with a very high maternal mortality. This lesion is an unusual complication of the preeclampsia-eclampsia syndrome. We report the case of a 34 years old woman who suffered this complication; responding satisfactorily after conservative surgical treatment.

We show a clinic case of a female patient 42 years old that suffered a myocardial infarction by coronary spasm, while she was in her 30th and a half weeks of gestation. We analyze the bases of the diagnostic its evolution and the neonatal complications.