1. [¿Azitromicina como tratamiento contra Chlamydia trachomatis?]
- Author
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Maldonado-Calderón JL, López-Márquez FC, and Ruiz-Flores P
- Subjects
- Anti-Bacterial Agents pharmacokinetics, Azithromycin pharmacokinetics, Chlamydia Infections diagnosis, Chlamydia Infections microbiology, Chlamydia trachomatis isolation & purification, Drug Administration Schedule, Drug Resistance, Bacterial, Female, Humans, Medication Adherence, Anti-Bacterial Agents administration & dosage, Azithromycin administration & dosage, Chlamydia Infections drug therapy
- Abstract
Azithromycin and doxycycline effectiveness has been demonstrated in the treatment of urogenital chlamydiasis, which has remained unchanged for a long time. Autoinoculation has been proposed as a method of reinfection and persistence of the disease in women and probably also owing to azithromycin pharmacokinetics in this tissue. With the new diagnostic methods and tests of cure, a difference has been demonstrated in favor of doxycycline in the treatment of rectal chlamydiasis Antimicrobial resistance has not played a relevant role since no treatment-resistant strains have been found in vivo. Nevertheless, azithromycin remains a first-choice drug, since it can be administered as a single dose, which favors therapeutic adherence., (Copyright: © 2018 SecretarÍa de Salud.)
- Published
- 2018
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