Search

In many cases, numb chin syndrome (NCS) may represent a banal pathology. However, as it can be associated with malignant processes, its presence should alert the clinician of a possible occult disease. In patients already diagnosed with cancer, it often represents an ominous sign that indicates poor prognosis, due to the rapid progress of the disease. The case is presented of a 62-year-old man diagnosed with synchronous lung and bladder cancer, who suddenly complained of numbness in the chin. The bone scan confirmed the suspicion of metastastic bone disease, and the patient died two months after the appearance of this sign., (Copyright © 2015 Elsevier España, S.L.U. y SEMNIM. All rights reserved.)

Metastatic tumors involve the oral cavity, and the most common primary sites are the breast and lung. Most cases affect the mandible and maxilla in that order, although some of them can be located in the soft perioral tissues. We report the case of a 62-year-old male who had been diagnosed with sigmoid adenocarcinoma with nodal and liver metastasis, who presented 6 months later with a gingival polypoid tumor, at first considered as a primary neoplasm of gingiva, that was diagnosed in a biopsy as metastatic intestinal adenocarcinoma. The histological evaluation is essential to separate adenocarcinoma from the commoner in this site squamous cell carcinoma, and the immunohistochemical techniques are useful to distinguish metastatic tumor versus primary adenocarcinoma from the minor salivary glands of the area. The intraoral spread of a disseminated neoplasm is generally a sign of bad prognosis, although a longer survival can be expected if a radical surgical treatment of a solitary metastasis is carried out.

Hepatocellular carcinoma (HCC) is quite uncommon in Europe and USA, although in this last country more than 13,000 new cases are diagnosed every year. Mandibular metastases are unusual, with only 50 cases documented. In this article, we present a 54 year-old male patient with a metastasis of HCC in right mandibular body, one year after treating the primary tumor. Curettage and biopsy of the lesion was performed, followed by a profuse hemorrhage. The patient expired six months after the biopsy, with multiple metastases. We describe the different paths for hematogenic dissemination of the process.

Thyroid carcinoma mandibular metastasis are not very frequent and the cases described in literature are few. Due to its bloodstream dissemination, most of them are a consequence of the follicular variant of thyroid carcinomas. A case is presented and a review of the clinicopathologic characteristics of the lesion is made, so the oral and maxilofacial surgeon can recognize it, make a correct differential diagnosis with other mandibular radioluciencies and in consequence, carry out an adequate treatment.

Introduction: The numb chin syndrome is characterized by oral and facial numbness restricted to the distribution of the mental nerve. This uncommon neuropathy has been described in association with a number conditions including malignant disease even in the patients no known to have cancer. Numb chin syndrome may be caused by metastatic involvement of the mental nerve, by involvement of the proximal mandibular root at the base of the skull or by intracranial leptomeningeal spread., Clinical Case/discussion: We described a case of neuropathy of the chin as the initial symptom of the breast cancer. We suggested that the lesion was in the trigeminal ganglion based on enlargement and gadolinium enhancement of the trigeminal ganglia on MRI. A mental neuropathy should initiate a search for cancer that includes MRI of the head.

Radiological techniques are important for studying the extension of laryngeal tumors. CT and MRI yield high-quality images with few artifacts that can be studied quickly. We reviewed the fundamental criteria for radiologic study of these tumors by ear, nose, and throat specialists on the basis of our personal experience and the literature.

We present the results of reconstructive surgery after different surgical resections in the oral cavity. Reconstruction of the defects was made using free microvascularized flaps. We used a free radial fasciocutaneous or osteocutaneous flap in every case, with a 100% of viability and a low complication rate. This technique is widely versatile in the reconstruction of different oral defects, offering an adequate replacement of oral mucosa.

Reporting a prostatic adenocarcinoma case which first manifestation was an osteogenic metastasis of the mandible. This is a very interesting event because of its unusual localization. Latest literature is reviewed.

We report a case of prostate carcinoma metastatic to the mandible that had been initially suspected as being a primary carcinoma of the parotid with lymph node metastasis. The present case underscores the diverse forms of manifestation of prostate carcinoma.

We present a case of squamous cell carcinoma of the lip with metástasis to the mandible and meningeal involvement causing multiple cranial nerve palsies. Biopsy proven metástasis to the mandible was demonstrated. Studies of CT scan of the head were negative. Extension through perineural space have been speculated.

We present a case of mandibular metastasis as the first manifestation of a disseminated prostate carcinoma. After commenting on the exceptional nature of the case, we underline the importance of histochemical markers (Acid phosphatase. PSA) to determine the non-filiated origin of a metastasis. It is advisable for this to be carried out systematically in all cases of metastasis of indeterminate origin.