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Mediation becomes relevant nowadays as a way to manage conflicts in the workplace in a nonjudicial way, preventing costly, extensive, and unsatisfying legal procedures. This study tries to systematize the more recent research about mediation, showing the main challenges, questions, and findings. Research suggests the importance of integrating the organizational and societal context in the study of mediation, the use of efficiency, equity, and voice objectives for evaluating mediation effectiveness, and taking into account a contingency approach in mediator strategies. There is an important gap between the large development of professional practice in mediation and the few systematic studies on this topic. This paper offers a model that considers current research and practice for mediation effectiveness. This model could be used to focus the orientation of scholars, practitioners, and governments in search of new developments in the design of mediation. Future research could explore specific combinations of these dimensions to analyze sectors, organizations, or cases of mediation.

Introduction: Biological therapies used for the treatment of inflammatory bowel disease (IBD) have shown to be effective and safe, although these results were obtained from studies involving mostly a young population, who are generally included in clinical trials. The aim of our study was to determine the efficacy and safety of the different biological treatments in the elderly population., Methods: Multicenter study was carried out in the GETECCU group. Patients diagnosed with IBD and aged over 65 years at the time of initiating biological therapy (infliximab, adalimumab, golimumab, ustekinumab or vedolizumab) were retrospectively included. Among the patients included, clinical response was assessed after drug induction (12 weeks of treatment) and at 52 weeks. Patients' colonoscopy data in week 52 were assessment, where available. Regarding complications, development of oncological events during follow-up and infectious processes occurring during biological treatment were collected (excluding bowel infection by cytomegalovirus)., Results: A total of 1090 patients were included. After induction, at approximately 12-14 weeks of treatment, 419 patients (39.6%) were in clinical remission, 502 patients (47.4%) had responded without remission and 137 patients (12.9%) had no response. At 52 weeks of treatment 442 patients (57.1%) had achieved clinical remission, 249 patients had responded without remission (32.2%) and 53 patients had no response to the treatment (6.8%). Before 52 weeks, 129 patients (14.8%) had discontinued treatment due to inefficacy, this being significantly higher (p<0.0001) for Golimumab - 9 patients (37.5%) - compared to the other biological treatments analyzed. With respect to tumor development, an oncological event was observed in 74 patients (6.9%): 30 patients (8%) on infliximab, 23 (7.14%) on adalimumab, 3 (11.1%) on golimumab, 10 (6.4%) on ustekinumab, and 8 (3.8%) on vedolizumab. The incidence was significantly lower (p=0.04) for the vedolizumab group compared to other treatments. As regards infections, these occurred in 160 patients during treatment (14.9%), with no differences between the different biologicals used (p=0.61): 61 patients (19.4%) on infliximab, 39 (12.5%) on adalimumab, 5 (17.8%) on golimumab, 22 (14.1%) on ustekinumab, and 34 (16.5%) on vedolizumab., Conclusions: Biological drug therapies have response rates in elderly patients similar to those described in the general population, Golimumab was the drug that was discontinued most frequently due to inefficacy. In our experience, tumor development was more frequent in patients who used anti-TNF therapies compared to other targets, although its incidence was generally low and that this is in line with younger patients based on previous literature., (Copyright © 2024 Elsevier España, S.L.U. All rights reserved.)

El presente trabajo analiza como se da la relación del gasto improductivo y la corrupción en México. Es un estudio descriptivo-exploratorio sobre el marco regulatorio del presupuesto y el gasto público, su ejercicio y la transparencia; se describe cómo opera éste, y cuales han sido los resultados. Se citan algunos ejemplos sobre el gasto improductivo y se esboza algunas recomendaciones y conclusiones.

Introduction: Reactivation of cytomegalovirus can complicate the evolution of patients with gastritis induced by immune checkpoint inhibitors., Methods: The experience in our center is described and a review of the literature is performed., Results: A case of severe gastritis induced by treatment with a programmed cell death receptor-1 (anti-PD1) inhibitor, associated with reactivation of cytomegalovirus (CMV) is described. In the systematic review, we identified 5 cases of immune-related gastritis associated with CMV reactivation. Ganciclovir treatment contributed to clinical improvement in most patients., Conclusion: The early identification of a CMV infection in patients with severe or refractory immune-related gastritis will allow the initiation of targeted treatment, and may avoid increasing immunosuppressive therapy., (Copyright © 2022 Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. Published by Elsevier España, S.L.U. All rights reserved.)

A study was carried out with one hundred and twenty one-week-old Hubbard broilers to determine the effect of replacing maize with cassava root meal (CRM) and maize/sorghum brewers’ dried grains (MSBDG) on performance of starter broilers. Four experimental diets were formulated to contain 0, 15, 30 and 45% CRM and MSBDG combined in the ratio of 1:1 in the broiler starter rations. There was no difference (P>0.05) in feed intake among the birds on 0, 15 and 45% CRM/MSBDG, but these were lower (P0.05) in daily weight gain among the birds on 0, 15 and 30 CRM/MSBDG diets, and each of these was higher than that of the birds on 45% CRM/MSBDG diet. The feed convertion ratio of 0% compared favourably with that of the birds on 15% diets, and these two diets were better (P

The status of marine turtles in Montserrat (Eastern Caribbean) is reviewed following five years of monitoring (1999-2003). The mean number of nests recorded during the annual nesting season (June-October) was 53 (± 24.9 SD; range: 13-43). In accordance with earlier reports, the nesting of hawksbill (Eretmochelys imbricata) and green (Chelonia mydas) turtles was confirmed on several beaches around the island. Only non-nesting emergences were documented for loggerhead turtles (Caretta caretta) and there was no evidence of nesting by leatherback turtles (Dermochelys coriacea); however, it is possible that additional survey effort would reveal low density nesting by these species. Officially reported turtle capture data for 1993-2003 suggest that a mean of 0.9 turtle per year (±1.2 SD; range: 0-4) were landed island-wide, with all harvest having occurred during the annual open season (1 October to 31 May). Informed observers believe that the harvest is significantly under-reported and that fishermen avoid declaring their catch by butchering turtles at sea (both during and outside the open season). Of concern is the fact that breeding adults are potentially included in the harvest, and that the open season partially coincides with the breeding season. The present study has shown that although Montserrat is not a major nesting site for sea turtles, it remains important on a regional basis for the Eastern Caribbean.