228 results on '"URETHRA"'
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2. Uretroplastia término terminal y reconstrucción cavernosa temprana en ruptura bilateral de origen traumático
- Author
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Vargas-Silva, Marcos David, Ortiz-Zableh, Ana María, Villareal-Trujillo, Nicolás, and Sarmiento-Sarmiento, Guillermo
- Subjects
pene ,erección peniana ,uretra ,heridas y lesiones ,procedimientos quirúrgicos reconstructivos ,penis ,penile erection ,urethra ,wounds and injuries ,reconstructive surgical procedures ,pênis ,ereção peniana ,ferimentos e lesões ,procedimentos cirúrgicos reconstrutivos ,Medicine - Abstract
Introducción. La fractura de pene es una emergencia urológica rara, se desconoce la incidencia real dado el subregistro causado por la reducida consulta de los pacientes, resultado del embarazoso contexto. En Estados Unidos alcanza un 38% donde la etiología de índole sexual predomina. En Colombia hay escasos reportes publicados. El diagnóstico de esta entidad es netamente clínico. El objetivo de este trabajo es reportar una evolución satisfactoria en términos de función miccional y eréctil en un paciente sometido a reconstrucción cavernosa y uretral temprana en rotura bilateral de origen traumático mediante una técnica quirúrgica poco convencional, de acuerdo con lo hallado en la literatura. Presentación del caso. Paciente masculino de 30 años, previamente sano, quien consultó al servicio de urgencias por uretrorragia, edema y dolor peneano secundario a trauma contuso del mismo durante relación sexual. El reporte ecográfico mostró disrupción en túnica albugínea del cuerpo esponjoso, hematoma y aparente transección uretral; se realizó exploración quirúrgica 6 horas después, con evidencia de fractura de cuerpos cavernosos, laceración del 40% de la circunferencia, transección completa de la uretra y cuerpo esponjoso. Se realizó rafia de cuerpos cavernosos y uretroplastia término terminal de uretra bulbar, con evolución clínica satisfactoria. Discusión. La reconstrucción quirúrgica en menos de 24 horas en fractura de pene disminuye significativamente la estancia hospitalaria y complicaciones precoces; asimismo, desciende el riesgo de disfunción eréctil, erecciones dolorosas y problemas miccionales. No hay publicaciones que comparen resultados a largo plazo entre los dos abordajes quirúrgicos. Conclusiones. La fractura de pene es una patología poco frecuente con diagnóstico clínico, la cual debe manejarse de manera temprana por cualquier urólogo y, en caso de ser posible, con experiencia reconstructiva y excelentes resultados en la función sexual y miccional. Introduction. Penile fracture is a rare urological emergency, the real incidence is unknown given the underreporting caused by the reduced consultation of patients, resulting from the embarrassing context. In the United States it reaches 38%, where sexual etiology predominates. In Colombia there are few published reports. The diagnosis of this entity is purely clinical. The aim of this work is to report a satisfactory evolution in terms of voiding and erectile function in a patient who underwent early cavernous and urethral reconstruction in bilateral rupture of traumatic origin by means of an unconventional surgical technique, in accordance with what has been found in the literature. Case Presentation. A 30-year-old male patient, previously healthy, consulted the emergency department for urethrorrhagia, edema and penile pain secondary to blunt trauma to the penis during sexual intercourse. The ultrasound report showed disruption in the tunica albuginea of the corpus spongiosum, hematoma and apparent urethral transection; surgical exploration was performed 6 hours later, with evidence of fracture of the corpora cavernosa, laceration of 40% of the circumference, complete transection of the urethra and corpus spongiosum. Sutures to the corpora cavernosa and end-to-end urethroplasty of the bulbar urethra were performed, with satisfactory clinical evolution. Discussion. Surgical reconstruction in less than 24 hours in penile fractures significantly reduces hospital stay and early complications; it also reduces the risk of erectile dysfunction, painful erections and voiding problems. There are no publications comparing long-term results between the two surgical approaches. Conclusions. Penile fracture is a rare pathology with clinical diagnosis, which should be managed early by any urologist and, if possible, with reconstructive experience and excellent results in sexual and voiding function. Introdução. A fratura peniana é uma emergência urológica rara, a real incidência é desconhecida dada a subnotificação causada pela reduzida consulta de pacientes, resultado do contexto constrangedor. Nos Estados Unidos chega a 38% onde predomina a etiologia de natureza sexual. Na Colômbia há poucos relatórios publicados. O diagnóstico desta entidade é puramente clínico. O objetivo deste trabalho é relatar uma evolução satisfatória da função miccional e erétil em um paciente submetido à reconstrução cavernosa e uretral precoce em ruptura bilateral de origem traumática por meio de técnica cirúrgica não convencional, de acordo com o que foi encontrado na literatura. Apresentação do caso. Paciente do sexo masculino, 30 anos, previamente saudável, procurou o pronto-socorro por uretrorragia, edema e dor peniana secundária a trauma contuso durante a relação sexual. O relatório do ultrassom mostrou ruptura na túnica albugínea do corpo esponjoso, hematoma e transecção uretral aparente; a exploração cirúrgica foi realizada 6 horas depois, com evidência de fratura dos corpos cavernosos, laceração de 40% da circunferência, transecção completa da uretra e corpo esponjoso. Foram realizadas ráfia dos corpos cavernosos e uretroplastia término-terminal da uretra bulbar, com evolução clínica satisfatória. Discussão. A reconstrução cirúrgica em menos de 24 horas nas fraturas penianas reduz significativamente o tempo de internação e as complicações precoces. Da mesma forma, diminui o risco de disfunção erétil, ereções dolorosas e problemas de micção. Não há publicações comparando os resultados a longo prazo entre as duas abordagens cirúrgicas. Conclusões. A fratura peniana é uma patologia rara com diagnóstico clínico, que deve ser tratada precocemente por qualquer urologista e, se possível, com experiência reconstrutiva e excelentes resultados na função sexual e miccional.
- Published
- 2022
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3. Outcomes of bulbar artery sparing during anastomotic urethroplasty for pelvic fracture urethral injury.
- Author
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Gómez RG, Velarde LG, Campos RA, Massouh R, Humerez V, and Barrientos V
- Subjects
- Humans, Adult, Male, Middle Aged, Young Adult, Treatment Outcome, Urologic Surgical Procedures, Male methods, Organ Sparing Treatments methods, Arteries injuries, Urethra injuries, Urethra surgery, Anastomosis, Surgical methods, Pelvic Bones injuries, Fractures, Bone surgery
- Abstract
Objective: To the present long-term outcomes of the vascular-sparing approach during reconstruction of pelvic fracture urethral injuries (PFUI) described by Gomez et al. MATERIAL AND METHODS: Anastomotic reconstruction of PFUI is performed without transecting the bulb of the spongiosum, to preserve the antegrade flow of the bulbar arteries. After exposure of the urethra, the bulbar arteries are located using a Doppler stethoscope. The bulb is mobilized dorsally and unilaterally, sacrificing the artery with the weaker Doppler signal to preserve the best contralateral artery. Occasionally, both arteries can be preserved. Removal of all fibrosis and anastomosis is performed as described in the traditional transecting technique., Results: A total of 60 patients were included, with a mean age of 37 years (IQR 22-48). The median time from trauma to urethral reconstruction was 16 weeks, and the mean stenosis length was 2.5 cm (IQR 2-3). The left bulbar artery was preserved in 27 cases, the right bulbar artery in 8, and both in 24. There were postoperative complications in 14 cases (23%), but only one of them was Clavien ≥ III. With a mean follow-up of 56 months (IQR 12-87), only one patient failed due to stenosis (98% success)., Conclusion: Preservation of antegrade arterial flow to the corpus spongiosum during PFUI reconstruction is feasible and safe. Although slightly more elaborate, this technique could reduce the risk of ischemic failure of reconstruction., Competing Interests: Declaration of competing interest Reynaldo Gómez: Proctor for Boston Scientific, Proctor for Rigicon. Laura Velarde: Proctor for Boston Scientific. The remaining authors declare that they have no conflicts of interest., (Copyright © 2024 AEU. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2025
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4. Randomized clinical trial on the use of IMAGE1 S LIGHT (SPIES) vs. white light in the prevention of recurrence during transurethral resection of bladder tumors: Analysis after 12-month follow-up.
- Author
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Trelles Guzmán CR, Linares Espinós E, Ríos González E, Alonso Dorrego JM, Aguilera Bazán A, Jiménez Romero ME, and Martínez-Piñeiro L
- Subjects
- Humans, Male, Female, Prospective Studies, Aged, Follow-Up Studies, Middle Aged, Time Factors, Single-Blind Method, Cystectomy methods, Light, Urethra, Urinary Bladder Neoplasms surgery, Urinary Bladder Neoplasms pathology, Neoplasm Recurrence, Local prevention & control, Neoplasm Recurrence, Local epidemiology
- Abstract
Introduction: The improved image resolution of IMAGE1 S technology will increase tumor detection, achieve a greater number of complete resections, and would probably have an impact on the reduction of recurrences., Aim: The primary objective was to compare the recurrence rates of IMAGE1 S vs. white light during transurethral resection of the bladder (TUR); the secondary objective was to compare the complication rates according to Clavien-Dindo (CD) at 12 months of follow-up., Methods: Prospective, randomized 1:1, blinded clinical trial. Recurrence and complication rates according to CD were analyzed using chi-square/U Mann-Whitney tests and recurrence-free survival (RFS) using Kaplan-Meier curves. The European Association of Urology (EAU) 2021 scoring model was used., Results: The analysis included 103 participants; 49 were assigned to the IMAGE1 S group and 54 to the white light group. Recurrence rates were 12.2% and 25.9%, respectively (P = .080). The low and intermediate risk group had a lower recurrence rate with IMAGE1 S (7.7% vs. 30.8%, P = .003) and a higher RFS with IMAGE1 S (85.2% vs. 62.8% Log Rank: 0.021), with a Hazard Ratio of 0.215 (95% CI: 0.046-0.925). No differences were observed in the high and very high-risk groups. Complications were mostly grade I and rates were similar between both groups (IMAGE1 S 20.4% vs. white light 7.4% P = .083)., Conclusions: There were no differences in the recurrence rates between groups. However, the low and intermediate risk group had a lower recurrence rate with IMAGE1 S. In addition, perioperative complication rates were not higher., (Copyright © 2023 AEU. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
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- View/download PDF
5. Uretroplastia término terminal y reconstrucción cavernosa temprana en ruptura bilateral de origen traumático
- Author
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Marcos David Vargas-Silva, Ana María Ortiz-Zableh, Nicolás Villareal-Trujillo, Guillermo Sarmiento-Sarmiento, Vargas Silva, Marcos David [0000-0001-7071-1391], Ortiz Zableh, Ana María [0000-0003-4152-9747], Villareal Trujillo, Nicolás [0000-0002-5974-8035], and Sarmiento Sarmiento, Guillermo [0000-0001-5492-7168]
- Subjects
Procedimientos quirúrgicos reconstructivos ,Pene ,Penile erection ,Wounds and injuries ,Erección peniana ,Medical sciences ,Life sciences ,Ciencias de la salud ,Urethra ,Reconstructive surgical procedures ,General Earth and Planetary Sciences ,Ciencias de la vida ,Uretra ,Heridas y lesiones ,Ciencias médicas ,General Environmental Science ,Penis - Abstract
La fractura de pene es una emergencia urológica rara, se desconoce la incidencia real dado el subregistro causado por la reducida consulta de los pacientes, resultado del embarazoso contexto. En Estados Unidos alcanza un 38% donde la etiología de índole sexual predomina. En Colombia hay escasos reportes publicados. El diagnóstico de esta entidad es netamente clínico. El objetivo de este trabajo es reportar una evolución satisfactoria en términos de función miccional y eréctil en un paciente sometido a reconstrucción cavernosa y uretral temprana en rotura bilateral de origen traumático mediante una técnica quirúrgica poco convencional, de acuerdo con lo hallado en la literatura. Presentación del caso. Paciente masculino de 30 años, previamente sano, quien consultó al servicio de urgencias por uretrorragia, edema y dolor peneano secundario a trauma contuso del mismo durante relación sexual. El reporte ecográfico mostró disrupción en túnica albugínea del cuerpo esponjoso, hematoma y aparente transección uretral; se realizó exploración quirúrgica 6 horas después, con evidencia de fractura de cuerpos cavernosos, laceración del 40% de la circunferencia, transección completa de la uretra y cuerpo esponjoso. Se realizó rafia de cuerpos cavernosos y uretroplastia término terminal de uretra bulbar, con evolución clínica satisfactoria. Discusión. La reconstrucción quirúrgica en menos de 24 horas en fractura de pene disminuye significativamente la estancia hospitalaria y complicaciones precoces; asimismo, desciende el riesgo de disfunción eréctil, erecciones dolorosas y problemas miccionales. No hay publicaciones que comparen resultados a largo plazo entre los dos abordajes quirúrgicos. Conclusiones. La fractura de pene es una patología poco frecuente con diagnóstico clínico, la cual debe manejarse de manera temprana por cualquier urólogo y, en caso de ser posible, con experiencia reconstructiva y excelentes resultados en la función sexual y miccional. Penile fracture is a rare urological emergency, the real incidence is unknown given the underreporting caused by the reduced consultation of patients, resulting from the embarrassing context. In the United States it reaches 38%, where sexual etiology predominates. In Colombia there are few published reports. The diagnosis of this entity is purely clinical. The aim of this work is to report a satisfactory evolution in terms of voiding and erectile function in a patient who underwent early cavernous and urethral reconstruction in bilateral rupture of traumatic origin by means of an unconventional surgical technique, in accordance with what has been found in the literature. Case Presentation. A 30-year-old male patient, previously healthy, consulted the emergency department for urethrorrhagia, edema and penile pain secondary to blunt trauma to the penis during sexual intercourse. The ultrasound report showed disruption in the tunica albuginea of the corpus spongiosum, hematoma and apparent urethral transection; surgical exploration was performed 6 hours later, with evidence of fracture of the corpora cavernosa, laceration of 40% of the circumference, complete transection of the urethra and corpus spongiosum. Sutures to the corpora cavernosa and end-to-end urethroplasty of the bulbar urethra were performed, with satisfactory clinical evolution. Discussion. Surgical reconstruction in less than 24 hours in penile fractures significantly reduces hospital stay and early complications; it also reduces the risk of erectile dysfunction, painful erections and voiding problems. There are no publications comparing long-term results between the two surgical approaches. Conclusions. Penile fracture is a rare pathology with clinical diagnosis, which should be managed early by any urologist and, if possible, with reconstructive experience and excellent results in sexual and voiding function.
- Published
- 2022
6. Satisfactoria evolución y sobrevida en una paciente portadora del carcinoma uretral A satisfactory progress and survival in a female patient suffering from urethral carcinoma. a case report
- Author
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Idelma Castillo García, Teresita Llera Clausell, Annia Dolores Gorte Quiñones, Ileana Armas Ampudia, and Rosa María Amador González
- Subjects
CARCINOMA ,URETRA ,URETHRA ,Medicine ,Medicine (General) ,R5-920 - Abstract
Se presenta un caso de una paciente femenina de la raza blanca, de 34 años de edad, con antecedentes de sepsis urinaria baja a recurrente, acude a la consulta externa del Hospital General Docente Abel Santamaría Cuadrado, sintiendo un ardor y dolor al orinar, disminución en el calibre del chorro de la orina, pujos y tenesmo vesical. Al examen físico se comprueba un tumor que emerge través del meato uretral, vascularizada color rojo violáceo, situada en la uretra anterior. Se realizan los exámenes complementarios e imageneológicos, los cuales se encuentran en los rangos del valor normal. Se realiza un tratamiento quirúrgico (exéresis de la tumoración, electrofulguración) y biopsia, resultando ser un carcinoma transcicional micro invasor con invasión linfática, completamente removido, y evolución clínica satisfactoria actualmente curada.A 34 year-old, Caucasian-female patient presenting a recurrent, low urinary sepsis came to the out-patient clinic at "Abel Santamaria Cuadrado" University Hospital complaining of burning and pain during the passing of urine, a diminution of urine stream and vesical tenesmus. At physical examination a tumor emerging from the urethral meatus was observed, having a red-purplish vascularization located in the anterior urethra. Complementary tests and imaging examinations were performed which ranges showed normal values. Surgical treatment (removal of the tumor and electro- fulguration) and a biopsy were performed which resulted in a micro-invasive transitional carcinoma having a lymphatic invasion completely removed, the patient showed a satisfactory clinical progress, currently cured.
- Published
- 2010
7. Carcinoma de Uretra en una gestante: presentación de un caso Urethral Carcinoma in a pregnant woman: a case report
- Author
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Teresita Llera Clausell, Rosa Maria Amador González, Idelma Castillo García, Ileana Armas Ampudia, and Pedro Hernández Campo
- Subjects
Carcinoma ,uretra ,urethra ,Medicine ,Medicine (General) ,R5-920 - Abstract
Paciente femenina de raza blanca, de 34 años de edad y 33 semanas de embarazo, acude al Cuerpo de Guardia del Hospital Clínico Quirúrgico «Abel Santamaría Cuadrado» en Pinar del Río, con sangrado genital cuando se le realiza el examen físico; se comprueba que sangra con facilidad a través del meato uretral, donde se observa que emerge una tumoración vascularizada situada en la uretra distal. Se realizan los exámenes complementarios e imagenológicos, los cuales se encuentran en rangos normales. Se realizó el tratamiento quirúrgico exéresis de la tumoración, electrofulguración y biopsia, resultando ser un carcinoma epidermoide moderadamente diferenciado, que infiltra la submucosa que fue completamente removido y cursó con evolución clínica satisfactoria. Actualmente está asintomática.A 34 year-old white female patient with 33 weeks of pregnancy, attended to the Emergency Room at "Abel Santamaria Cuadrado" University Hospital in Pinar del Rio presenting genital bleeding at physical examination; corroborating ease bleeding through the meatus urethrae and observing the appearance of a vascularized tumor in the distal urethra. Complementary and imaging examinations were performed being in normal ranks. Surgical treatment was carried out removing the tumor, performing the electrofulguration and biopsy which resulted in a moderately differentiate epidermoid carcinoma, that infiltrated the submucosa, completely removed having the patient a clinical satisfactory progress, currently asymptomatic.
- Published
- 2009
8. Surgical management of urethral prolapse in pediatrics: A case report
- Author
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Guerrero-Villota, J. Cristina, Dueñas-Dasilva, Manuel F., Polania-Quintero, Juan Camilo, Figueroa-Gutiérrez, Luis Mauricio, and Dueñas-Ramírez, Juan Carlos
- Subjects
uretra ,surgery ,pediatrics ,pediatría ,prolapso ,conservative treatment ,urethra ,cirugía ,tratamiento conservador ,prolapse - Abstract
Resumen Introducción. El prolapso uretral es una entidad poco común, con una incidencia estimada de 1 en 3000 mujeres. Se presenta cuando la mucosa uretral sobresale espontáneamente más allá del meato uretral. Es una patología poco diagnosticada dada su baja frecuencia y de allí la importancia de conocer sobre su presentación, diagnóstico y tratamiento. El objetivo de este artículo fue presentar el caso de una paciente de 10 años con diagnóstico de prolapso uretral y su manejo quirúrgico. Caso clínico. Paciente femenina de 10 años, que consultó por cuadro clínico de 1 año de evolución consistente en dolor en región urogenital, que se irradiaba a hipogastrio, asociado a pujo y disuria, a quien se le diagnosticó prolapso uretral y se realizó corrección quirúrgica de mucosa uretral prolapsada mediante técnica de Kelly-Burnham modificada. Conclusión. El prolapso uretral es una entidad que con frecuencia es diagnosticada erróneamente pues su diagnóstico es eminentemente clínico. Si bien se ha descrito el tratamiento médico en primera instancia, éste tiene una alta tasa de recurrencia, por lo que en estos casos se prefiere la resección quirúrgica del tejido prolapsado. Abstract Introduction. Urethral prolapse is a rare entity, with an estimated incidence of 1 in 3,000 women. It occurs when the urethral mucosa spontaneously protrudes beyond the urethral meatus. It is a poorly diagnosed pathology given its low frequency and hence the importance of knowing about its presentation, diagnosis and treatment. The objective of this article was to present the case of a 10-year-old patient with a diagnosis of urethral prolapse and its surgical management. Clinical case. A 10-year-old female patient, who consulted for a 1-year clinical picture consisting of pain in the urogenital region, radiating to the hypogastrium, associated with pushing and dysuria, who was diagnosed with urethral prolapse and a surgical correction of the urethral mucosa was performed prolapsed by modified Kelly-Burnham technique. Conclusion. Urethral prolapse is an entity that is frequently misdiagnosed because its diagnosis is eminently clinical. Although medical treatment has been described in the first instance, it has a high recurrence rate, so surgical resection of the prolapsed tissue is preferred in these cases.
- Published
- 2022
9. Parauretral leiomioma: unusual clinical manifestation, first case report in colombian literatura
- Author
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Fares-Kamis, Ali, Torrado-Arenas, Daniel Mauricio, Omaña-Roa, Jhon Jairo, Rodríguez, Paula, Mena-Galviz, Liseth Susana, and Mercado-López, Ignacio Vicente
- Subjects
Ultrasonografía ,Leiomyoma ,Urethra ,Vagina ,Colpotomía ,Leiomioma ,Colpotomy ,Uretra ,Ultrasonography - Abstract
RESUMEN El leiomioma parauretral es una neoplasia benigna con pocos casos descritos en la literatura. El leiomioma abarca el 5% de los casos de las masas parauretrales, ocupando el cuarto lugar como una de las causas menos frecuentes, después del divertículo parauretral. Se presenta el caso de una paciente de 43 años con antecedente de infección urinaria a repetición, con una masa de 8 cm en pared vaginal anterior de cuatro años de evolución. La cistoscopia fue normal y la ecografía mostró una lesión sólida parauretral. Se realizó resección por colpotomía sin complicaciones, con resultado de patología de leiomioma. Control postquirúrgico y uroflujometría normal. Dentro de las posibilidades diagnósticas ante una masa parauretral, el leiomioma debe considerarse. La sintomatología es variable, siendo los síntomas urinarios los más frecuentes. La ecografía y la resonancia son herramientas fundamentales y el manejo se basa en la resección quirúrgica, generalmente vía vaginal. MÉD.UIS.2021;34(2): 77-82. ABSTRACT Introduction: Paraurethral leiomyoma is a rare benign neoplasm, with few cases described in the literature. Most of the data on prevalence are based on case series, the leiomyoma covers 5% of the paraurethral masses, occupying the fourth place as one of the less frequent causes, after parurethral diverticulum. Case: 43 years old patient with antecedents of recurring urinary infections and a previous 8 cm mass on the vaginal walls with 4 years of clinical evolution course. Cystoscopy was normal and ultrasound with a solid paraurethral injury. Colpotomy resection was performed without complications, resulting in leiomyoma pathology. Post-surgical control and normal uroflowmetry. Discussion and conclusion: leiomyomas should be considered as a possible diagnosis in case of a periurethral mass presence. Symptomatology is variable. The urinary symptoms are the most frequent as in this case. Ultrasonography and resonance are essential tools treatment are based on surgical resection which is usually vaginally. MÉD.UIS.2021;34(2): 77-82
- Published
- 2021
10. La baja utilidad de la determinación del ADN del VPH en la región distal de la uretra masculina Low usefulness of HPV DNA determination in the distal region of the male urethra
- Author
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Ahideé G Leyva-López, Carlos E Aranda-Flores, Carlos Conde-González, and Eduardo C Lazcano-Ponce
- Subjects
papilomavirus humano ,reacción en cadena de la polimerasa ,hombres ,uretra ,México ,papillomavirus ,human ,polymerase chain reaction ,men ,urethra ,Mexico ,Public aspects of medicine ,RA1-1270 - Abstract
OBJETIVO: Determinar la prevalencia uretral del ácido desoxirribonucleico del virus de papiloma humano, condilomatosis clínica y subclínica, en hombres cuyas parejas sexuales tuvieron el antecedente de neoplasia intraepitelial cervical. MATERIAL Y MÉTODOS: De octubre de 1997 a agosto de 1998 se hizo un estudio transversal; se incluyeron 200 hombres de entre 17 a 64 años de edad, referidos a la Coordinación de Oncología del Instituto Nacional de Perinatología, de la Ciudad de México, porque sus parejas regulares sexuales tuvieron el antecedente de neoplasia intraepitelial cervical. Se llevó a cabo un examen físico del pene (penoscopía) con la aplicación de ácido acético a 3-5%, y con el uso de un colposcopio se localizaron y evaluaron zonas acetoblancas y cambios vasculares, interpretados como anormales, asociados con la infección por el virus del papiloma humano. La determinación del ADN de VPH se verificó por PCR e hibridación en línea reversa. El análisis estadístico exploratorio y univariante se realizó con el paquete Stata V6.0. RESULTADOS: En las 200 muestras recolectadas de células exfoliadas de la uretra el gen de beta-globina estuvo presente en 93.5% (187/200), y el ácido desoxirribonucleico del virus del papiloma humano fue detectable solamente en 2% (4/187) de los sujetos. Por medio de la penoscopía se observó la presencia de zonas acetoblancas en 43% (81/187) de los sujetos. CONCLUSIONES: En este estudio se observa que la presencia del ácido desoxirribonucleico del virus del papiloma humano en la uretra masculina es poco común, como lo reportan estudios internacionales. Es necesario realizar investigaciones que evalúen esta presencia en glande y surco balano prepucial, en comparación con la región distal de la uretra.OBJECTIVE: To assess the prevalence of Human Papillomavirus (HPV) Deoxyribonucleic acid (DNA), and of clinical and subclinical condilomatosis in men whose sex partners had been diagnosed with cervical intraepithelial neoplasia. MATERIAL AND METHODS: A cross-sectional study was conducted from October 1997 to August 1998, among 200 men aged 17 to 64 years referred to the Oncology Department of the National Institute of Perinatology in Mexico City. A physical examination of the penis (penoscopy) was performed after applying 3-5% acetic acid. A colposcope was used to identify acetowhite areas and vascular abnormalities associated with HPV infection. HPV DNA was detected by PCR and reverse line hybridization. The exploratory and univariant statistical analysis was made with the package Stata V6.0. RESULTS: The beta-globin gene was present in 93.5% (n=187) of the 200 urethral exfoliated cell samples collected. HPV DNA was detected in only 2% (4/187) of the study subjects. Penoscopy data showed the presence of acetowhite areas in 43% (81/187) of subjects. CONCLUSIONS: Study findings show that the presence of HPV DNA in urethra is uncommon, as has been reported in several previous studies. Research is needed to evaluate the presence of HPV DNA in the coronal sulcus, as compared with the distal urethral region.
- Published
- 2003
11. Leiomioma uretral durante a gravidez: relato de caso Urethral leiomyoma during pregnancy: a case report
- Author
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Arlon Breno Figueiredo Nunes da Silveira, Cássio Luis Zanettini Riccetto, Viviane Herrmann, Paulo César Rodrigues Palma, and Juliane de Fátima Agostini Tiecher
- Subjects
Neoplasms ,Urethral neoplasms ,Leiomyoma ,Urethra ,Pregnancy ,Surgery ,RD1-811 - Abstract
The authors report a case of urethral leiomyoma diagnosed during pregnancy, which was conservatively treated up to the 38th week, when the pregnancy was interrupted. Thirty days after delivery, exeresis of the lesion was performed from the upper border of the urethral meatus and sutured with interrupted delayed-absorbable suture. The patient evolved favorably and presented no lesion recurrence during three months of follow up.
- Published
- 2012
12. Consequences of penile fracture: Complications and long-term functional outcomes.
- Author
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Peradejordi Font MR, Mercader Barrull C, López Martínez JM, Corral Molina JM, García Cruz E, Alcaraz Asensio A, and Peri Cusi L
- Subjects
- Humans, Male, Retrospective Studies, Urethra surgery, Urethral Stricture etiology, Penis injuries, Penis surgery
- Abstract
Introduction: Penile fracture (PF) is a urological emergency with low incidence, and evidence of its long-term outcomes is scarce. This study focuses on postoperative complications and long-term functional outcomes in patients with PF and surgical repair at our center., Materials and Method: Clinical records of patients undergoing urgent surgery for PF at a third level hospital between 2006 and 2020 were retrospectively reviewed. Functional outcomes were assessed with voluntary telephone interviews from June 2020 to February 2021. Lower urinary tract symptoms were screened by IPSS questionnaire, sexual function by EHS and IIEF-5 and morphological alterations by direct questions to patients., Results: A total of 41 patients underwent surgery for PF. Eleven of them also had urethral injury (higher incidence if there was bilateral corpora cavernosa injury, 19.4% vs. 80%, p < 0.05). Only 1 patient presented a Clavien-Dindo type 3a complication due to wound dehiscence, 4 (13%) type 2 and 9 (29%) type 1. Twenty-four patients underwent long-term follow-up, of whom 20 (83.3%) presented normal sexual function. Twelve patients (50%) had a palpable nodule at the fracture site, 8 (33.3%) had new onset penile curvature and 1 patient with previous urethral injury presented urethral stricture., Conclusion: In cases of penile fracture, there is a higher incidence of urethral injury if both corpora cavernosa are affected. Long-term functional sequelae after surgical repair of a PF are rare., (Copyright © 2022 AEU. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2022
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13. Caracterización clinicoepidemiológica y terapéutica de pacientes con hipospadias Clinical epidemiologic and therapeutic characterization of patients with hypospadias
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Manuel Pantoja Blanco, Edward Kofi Boache, Gilberto Rio Hidalgo, Oscar Luis Sánchez Ramírez, and Rafael Antonio Camué Moya
- Subjects
HIPOSPADIAS ,ANOMALÍAS CONGÉNITAS ,PENE ,URETRA ,COMPLICACIONES POSTOPERATORIAS ,HYPOSPADIAS ,CONGENITAL ABNORMALITIES ,PENIS ,URETHRA ,POSTOPERATIVE COMPLICATIONS ,Medicine (General) ,R5-920 ,Internal medicine ,RC31-1245 - Abstract
La hipospadia es una de las malformaciones congénitas más frecuentemente observadas en la práctica de la cirugía pediátrica urológica a escala mundial y una de las causas de consultas iteradas en este territorio. A los efectos se realizó un estudio descriptivo, observacional y retrospectivo de 108 niños con el diagnóstico de hipospadia, atendidos en el Servicio de Urología del Hospital Pediátrico Sur de Santiago de Cuba, durante el período comprendido desde enero del 2000 hasta diciembre del 2006. El análisis efectuado reveló un predominio de los pacientes de 1 a 4 años y de la técnica quirúrgica de Snodgrass para la ejecución de la uretroplastia. La evolución clínica general resultó satisfactoria en 52,8 % de los integrantes de la serie, pues los restantes requirieron nuevas intervenciones.Hypospadias is one of the more frequently observed congenital malformations in the worldwide urologic pediatric practice and one of the reasons for repeated visits in this territory. In this respect a descriptive, observational and retrospective study was carried out in 108 children with diagnosis of hypospadias, who were attended in the Service of Urology of the Southern Children Hospital of Santiago de Cuba, from January, 2000 to December, 2006. The analysis revealed prevalence of patients aged between 1 and 4 years and of the Snodgrass's surgical technique for the urethroplasty. The general clinical course was satisfactory in 52,8% of the series patients, and the remainder required new interventions.
- Published
- 2009
14. Prognostic value of urinary cytology for detecting urothelial carcinoma recurrence after radical cystectomy.
- Author
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Rodríguez-Serrano A, Carrión DM, Gómez Rivas J, Álvarez-Maestro M, Sánchez S, Rodríguez de Bethencourt F, Aguilera Bazán A, and Martínez-Piñeiro L
- Subjects
- Cystectomy, Humans, Male, Neoplasm Recurrence, Local diagnosis, Prognosis, Retrospective Studies, Urethra, Carcinoma, Transitional Cell diagnosis, Urinary Bladder Neoplasms diagnosis
- Abstract
Introduction: Urethral or upper urinary tract (UUT) recurrence of urothelial carcinoma (UC) after radical cystectomy (RC) are rare (4-6%), and their diagnosis usually occurs within the first two years. Although it is known that its early detection offers benefit in terms of survival, currently there are no clear recommendations for the detection of recurrence in the remnant urothelium (RU). Our aim is to determine the diagnostic value of urinary cytology for the detection of recurrences in the RU and to estimate its impact as an early diagnostic method on survival., Material and Methods: Retrospective review of patients who underwent RC for urothelial carcinoma between 2008-2016, with a follow-up of at least 24 months., Results: The study included 142 patients. In a median follow-up of 68.5 months, nine patients (6.3%) presented recurrences in the RU (urethra: four, UUT: four, synchronous: one). The sensitivity and specificity of urinary cytology for the diagnosis of UUT recurrences were 20% and 96%, respectively. No significant differences were found between overall survival and cancer-specific survival among patients according to the urinary cytology results., Conclusion: Recurrences in the RU after RC are infrequent; our study has shown that urinary cytology offers a low sensitivity for their diagnoses. For these reasons, we do not consider that urinary cytology provides useful information for surveillance of these patients., (Copyright © 2020 AEU. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2021
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15. [Predictors of complex urethral surgery in anterior urethral stricture disease.]
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Favre G, Gil S, Carminatti T, Tobia I, Giudice C, and Giudice C
- Subjects
- Cross-Sectional Studies, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Urethra, Urologic Surgical Procedures, Male, Urethral Stricture surgery
- Abstract
Objective: To determine the clinical-surgical factors associated with Complex Urethral Surgery (CUC) in anterior urethral stenosis., Material and Method: This is a cross-sectional study with retrospective data recording, including all male patients who under went anterior urethroplasty between 2011 and 2018. CUC included two or more grafts urethroplasty, excisional augmented anastomotic urethroplasty, combined flaps and grafts urethroplasty and stages surgery. The data were collected from the electronic medical record, recording the demographic data, background of previous treatments as well as the characteristics of the stenosis (etiology, anatomical location, length, number of strictures, among others). A univariate and multivariate analysis were conducted using the chi-squared test and logistic regression to identify the variables related to CUC., Results: The data of 665 patients met the inclusion criteria were analyzed. The mean age was 56.1 years, 27.5% were smokers, 32.5% had received some previous treatment, and dilatations were the most common procedure. The most prevalent etiology was iatrogenic, followed by idiopathic in a 61.1 and 20.3% respectively. Bulbar urethral stricture were the most common location (56.2%) while the mean length of the stenosis was 4.8 cm. After univariate and multivariate analysis, previous dilations (HR 2.6), multifocality (2.51), lengthof stenosis (>4 cm) (HR 1.49) and the hypospadias etiology (HR 11.9) were independent predictors for CUC (p<0.05)CONCLUSIONS: Hypospadias was the only etiology factor that predicts the need for CUC. Regarding radiological findings, extensive and multifocal stenosis, were predictors of complex surgery. History of previous dilations were also predictors of CUC.
- Published
- 2021
16. [Pediatric foreign body. A two case report.]
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Fadil Iturralde JL, Marani J, Contardi JC, and Damiani H
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- Child, Child, Preschool, Emergency Service, Hospital, Humans, Male, Radiography, Sexual Behavior, Urethra diagnostic imaging, Urethra surgery, Foreign Bodies diagnostic imaging, Foreign Bodies surgery
- Abstract
Introduction: Urethral insertion of foreign bodies is an infrequent emergency, being it exceptionally rare in prepubertal children. Both clinical presentation and the introduced elements are varied. Although sexualabuse and mental disorders must always be considered, these events are mainly related to the children's own body self-discovery without any sexual connotation. Endourologic approach is the treatment of choice while the need for conventional surgery is unusual., Objective: To review clinical and therapeutic aspects of the insertion of urethral foreign bodies in early childhood, and to report two new clinical cases., Materials and Methods: A 7-year-old boy and a 5-year-old boy, brought to emergency for referring the insertion of a metallic foreign body in the urethra. Both were oligosymptomatic, and the diagnosis was confirmed by radiology. They were treated with an endourological approach without any complications., Conclusion: The introduction of foreign bodies in the urinary tract is an unusual problem in prepubertal children. Theirs approach must be individualized, not only limited to the removal of the foreign body but also to the exclusion of child abuse and psychiatric disorders.
- Published
- 2021
17. Using «stonebreaker» (Phyllantus niruri) as therapy for struvite urolithiasis in a pet rabbit (Oryctolagus cuniculus)
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G Jesús Lescano, Alberto Sato Sato, and U Miryam Quevedo
- Subjects
fosfato amónico-magnésico ,medicine.medical_specialty ,Abdominal pain ,ammonium-magnesium phosphate ,General Veterinary ,business.industry ,Urinary system ,Radiologic examination ,Ammonium magnesium phosphate ,lagomorph ,phytotherapy ,Gastroenterology ,cálculos ,Alternative treatment ,Urethra ,medicine.anatomical_structure ,Internal medicine ,calculi ,lagomorfo ,Medicine ,Dysuria ,Ultrasonography ,medicine.symptom ,fitoterapia ,business - Abstract
La urolitiasis es una enfermedad común en animales de compañía, pero su etiopatogénesis y frecuencia es poco conocida en conejos. El tratamiento convencional sugerido puede ser quirúrgico o médico; sin embargo, el tratamiento alternativo basado en el uso de la planta «chancapiedra» (Phyllantus niruri) es comúnmente empleado en casos de urolitiasis humana en la medicina tradicional peruana, aunque se desconocen sus mecanismos farmacológicos. Se reporta el caso de un conejo macho que presentaba disuria y dolor a la palpación abdominal. El examen radiográfico reveló la presencia de un cuerpo radiopaco en la uretra. Se diagnosticó urolitiasis y se programó el tratamiento quirúrgico para el día siguiente, sugiriéndose como terapia complementaria la infusión de «chancapiedra» como agua de bebida. Al día siguiente el propietario halló el urolito cerca al dormidero de su mascota y el examen ultrasonográfico reveló la ausencia del cálculo en el tracto urinario del animal. El examen de laboratorio indicó que el urolito estaba compuesto de fosfato amónico-magnésico., Urolithiasis is a common disease in companion animals, but the etiopathogenesis and frequency in rabbits is poorly known. Conventional therapy can be surgical or medical. An alternative treatment based on the use of the plant «stonebreaker» (Phyllantus niruri) is commonly used in human urolithiasis in Peruvian traditional medicine, despite pharmacologic mechanisms are not completely understood yet. It is reported the case of a male rabbit showing dysuria and abdominal pain. Radiologic examination revealed the presence of a radiopaque body in the urethra. Urolithiasis was diagnosed, surgery was scheduled for the next morning and «stonebreaker» tea was suggested as a complementary therapy. The following day the owner found the urolith near the pet’s hutch. Ultrasonography revealed the absence of calculus in the urinary tract. Laboratory analysis revealed the urolith was composed by ammonium magnesium phosphate.
- Published
- 2015
18. Deteccion de Chlamydia trachomatis en muestras uretrales mediante inmunofluorescencia directa Detecção de Chlamydia trachomatis em amostras uretrais mediante imunofluorescência direta Detection of Chlamydia trachomatis in urethral samples by means of direct immunofluorescence
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Myra Wilson Schuster, Laura Otth R., Maria Angélica Gutiérrez E., Angela Tejero P., Maria Isabel Moreno V., and Mónica Hering
- Subjects
Chlamydia Trachomatis ,Uretra ,Inmunofluorescencia ,Chlamydia trachomatis ,Imunofluorescência ,Urethra ,Fluorescent antibody technic ,Public aspects of medicine ,RA1-1270 - Abstract
Se estudiaron 82 pacientes con uretritis para la búsqueda de Chlamydia trachomatis mediante inmunofluorescencia directa, Neisscria gonorrhoeae, Mycoplastna y Ureaplasma mediante métodos estándar. Se encontró un 19,5% de Chlamydia trachomatis y en 11 de ellos (68,8%) se encontró asociada a otras bacterias y estos pacientes presentó una secreción escasa-gelatinosa.Em 82 doentes com uretrite foi pesquisada a presença de Chlamydia trachomatis, utilizando a prova da imunofluorescência direta, e de Neisseria gonorrhoeae, Mycoplasma e Ureaplasma, utilizando os métodos padrões. Ch. trachomatis foi encontrada em 19,5% dos casos, sendo que em 11 deles (68,8%) observou-se associação entre Chlamydia e as outras bactérias pesquisadas. Nesses pacientes observou-se presença de secreção uretral escassa e de aspecto gelatinoso.The presence of Chlamydia trachomatis was studied by the direct immunofluorescence test, as also was that of Neisseria gonorrhoeae, Mycoplasma and Ureaplasma by the standard methods, in 82 patients with urethral discharge. Ch. trachomatis was found in 19.5% (16) of the cases and in 11 of them (68.8%) there was association with the other bacteria investigated. This eleven patients presented a scanty gelatinous discharge.
- Published
- 1989
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19. [Long term results of congenital penile curvature treated with cavernosa corpora rotation.]
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Molina Escudero R, Rodríguez Sánchez L, Herranz Yagüe JA, Arnaiz Pérez AR, Álvarez Ardura M, and Páez Borda Á
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- Adult, Female, Humans, Male, Rotation, Urethra, Uterus, Penile Diseases therapy, Penile Erection
- Abstract
Introduction: Congenital penile curvature (PCC) is a disorder caused by an alteration in the embryonic development of the urethra and the corporacavernosa, which causes difficulty in penetration, requiring surgical correction when inter course is impossible., Objective: To analyze the results of the surgical treatment of the IPC by means of rotation of the corpora cavernosa (RCC) described and modified by Shaeer. PATIENTS AND METHODS: Ten patients diagnosed with PCC with impossibility to inter course, were operated in a period of 36 months. Prior to the intervention,we applied the IIEF-5 questionnaire, measured the length of the penis and the angle of curvature throughself-photographs in three projections. By subcoronal approach,we perform denudation of the penis. On both sides of the urethra we incised Buck's fascia and released the neurovascular bundle from the ventral to the dorsal side. We generate an artificial erection evidencing the curvature. On the dorsal aspect of both corpora cavernosa, we made two incisions in the external longitudinal layer of the tunica albuginea. We sutured the internal and external edges of both incisions together with a 4/0 non-reabsorbable monofilament continuous suture, checking the correction of the curvature by means of an artificial erection. The patients were discharged the day after the intervention. The penile length and curvature were determined in the sixth month, and the IIEF-5 questionnaire. For the comparison of means we used the Mann-Whitney U test. RESULTS: The mean age was 26.8 years. The average follow-up was 20.7 months (12-31) and the median was 24. Before the intervention, the average curvature was 68.5° (50-90°); the average length 14.2 cm (10-18) and the IIEF-5 of 21. After surgery, the average length was 13.7 cm, the residual curvature the IIEF-5 of 25. There were no statistically significant differences between pre and postoperative penile length,(p=0.08). Nine patients assured that they would under go the same intervention again. CONCLUSIONS: RCC is an effective therapeutic alternative to the techniques of plication or lengthening of the tunica albuginea for the treatment of PCC, main tainingits long-term results.
- Published
- 2020
20. [20 years urethroplasty experience. Retrospective review and outcomes.]
- Author
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Lozano JL, Ruiz S, Fernández R, Gutiérrez G, Iturregui AM, and Anton M
- Subjects
- Humans, Male, Mouth Mucosa transplantation, Retrospective Studies, Treatment Outcome, Urethra, Urethral Stricture, Urologic Surgical Procedures, Male
- Abstract
Objective: To present the evolution in the diagnosis and treatment of urethral stricture, after performing 300 surgical procedures over urethral meatus,penile and bulbar urethra along 20 years, contrasting two surgical periods: from 1997-2006 to 2007-2016. MATERIAL AND METHODS: A retrospective review of495 medical records between 1997-2016 was conducted.All the patients treated with urethroplasty were included and those who under went internal urethrotomy,stents or dilatations plus those with strictures due to prostate cancer treatment or orthotopic neobladder were excluded. RESULTS: 300 patients were selected: 100 patients within the first period (1997-2006) and 200 within the second (2007-2016). The median follow-up was 36 months (range 12-60). In relation to the surgical techniques, among the most employed, four are outstanding so their results can be compared in both periods:termino-terminal urethroplasty, penile flap urethroplasty and the buccal mucosa in penile or bulbar urethroplasty.Other techniques were incorporated during the second period. The best outcomes were provided by end' to endurethroplasty with 90 and 92% success. Over the second period, buccal mucosa indications were consolidated with an increase use from 16% to 56%. Were considered as successful those patients that did not need any endoscopic procedure and reporting excellent urinary flow without low urinary tract symptoms. CONCLUSIONS: A trend towards an increased usage of open surgery vs urethrotomy is observed. Buccal mucosa graft has been consolidated as a reconstructive technique. End-to end urethroplasty seems to provide the best functional outcomes.
- Published
- 2020
21. [Urethral prolapse in a girl with urogenital bleeding].
- Author
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González Miares C, Fuentes Carretero S, Pradillos Serna JM, and Ardela Díaz E
- Subjects
- Child, Female, Humans, Pelvic Organ Prolapse surgery, Urethral Diseases surgery, Hemorrhage etiology, Pelvic Organ Prolapse complications, Urethral Diseases complications
- Abstract
Urethral prolapse is an uncommon condition that involves the distal urethra. It occurs most often in prepuberal black girls and in postmenopausal women. The reason for consultation is usually genital bleeding and/or dysuria. The treatment includes from conservative therapy to surgical interventions. We present the case of an 11-year-old white girl who came to the Emergency Room due to vaginal discharge for 6 days and genital bleeding for 3 days that was accompanied by stabbing pain in genital region, with occasional dysuria. A circular eversion of the urethral mucosa was observed, so the patient was surgically intervened, performing a prolapse resection with clinical resolution., Competing Interests: The authors report no conflicts of interest in this work., (Sociedad Argentina de Pediatría.)
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- 2020
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22. [Second-line treatment in recurrent urinary incontinence after the use of mid-urethral tapes. Systematic review and metaanalysis of proportions.]
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Vega-López J, Sánchez-Moreno D, and Durán-Torres F
- Subjects
- Female, Humans, Treatment Outcome, Urethra, Urologic Surgical Procedures, Suburethral Slings, Urinary Incontinence, Stress surgery
- Abstract
Objective: Female urinary incontinence has a prevalence of up to 40%. Stress urinary incontinence is the most frequent type, about 50%. When primary management fails, it is unclear what the behavior should be. This study aims to show the cure rate of the second-line management options described in the literature., Material and Method: Systematic review of the literature with meta-analysis of proportions. Observational and interventional studies were included in which the different types of management of recurrent/persistent urinary incontinence were evaluated in women who had a mid-urethral tape as primary management., Results: 161 studies were identified and screened, including 29 in the qualitative synthesis and 27 in the quantitative synthesis. Given the high clinical and methodological heterogeneity, an estimation of the cure rate for each type of management was performed, with the following results regarding the total combined cure rate: in the implantation of adjustable tapes of 86% ( IC95%: 76.4% -92.1%), the implantation of a second mid urethral tape was 75.1% (95% CI: 68% -81.1%), in the shortening of the previous mid urethral tape was 62.3% (95% CI: 49.1% -73.9%) and finally the implantation of bulking agents was 55.4% (95% CI: 43.2% -67%). We did not find enough studies to perform a quantitative synthesis with respect to: pubovaginal sling, colposuspension and pelvic floor therapy, as well as secondary outcomes., Conclusion: The evidence found shows that there may be superiority of the adjustable tapes versus the mid urethral tapes and other included treatments. However, a comparison to statistically corroborate this difference could not be made. These results should be confirmed with multicenter collaborative randomized clinical trials.
- Published
- 2019
23. [Comparative analysis of the treatment of mid-shaft and distal hypospadias according to Snodgrass surgical repair and Mathieu technique.]
- Author
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García-González M, Casal-Beloy I, Somoza Argibay I, and Dargallo Carbonell T
- Subjects
- Child, Child, Preschool, Humans, Infant, Male, Penis, Retrospective Studies, Treatment Outcome, Urethra, Urologic Surgical Procedures, Male, Fistula, Hypospadias surgery
- Abstract
Objective: The objective of this study is to perform an analysis of the patients who underwent middle and distal penile hypospadias repair using the two most widely used techniques in our Pediatric Urology Unit. MATERIAL AND METHODS: We perform a retrospective analysis of patients with a diagnosis of middle penile and distal penile hypospadias and operated by the Snodgrass or Mathieu technique, between 2011 and 2016 ensuring minimal follow-up of one year. We will analyze the use of each one, the results obtained, and the possible factors that could influence their success rate., Results: A total of 80 patients were included in the study, with a median age of 28 months at surgery (Range: 11 to 151). There were 34 patients (42.5%) with Snodgrass technique and there were 46 patients (57.5%) with Mathieu technique. We have not identified statistically significant differences in complications between both surgical techniques. The percentage of fistulas is higher in Snodgrass urethroplasty (12.1% vs 8.9%), decreasing in the last years of the series, at the same time meatal stenosis is higher in Snodgrass technique (3% vs 2.2%) while the meatal retraction is higher in the urethroplasty of Mathieu (20% vs 15.2%). CONCLUSIONS: The exhaustive selection of patients seems the key in the succesful correction of these types of hypospadias. Despite both techniques are comparable in terms of the type of patient in which they could be applied and both techniques present similar rates in terms of fistulas and stenosis/retractions of the neomeatus (most frequent complications in this type of repairs), we consider that the characteristics of the patient should be prioritized before the preference of the surgeon to reach higher success rates.
- Published
- 2019
24. Deficiencia intrínseca esfinteriana: ¿Qué papel juega la hipermotilidad en su manejo?
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Salazar-González, Alejandra and Echavarría-Restrepo, Luis Guillermo
- Subjects
uretra ,urodinámica ,incontinencia urinaria de esfuerzo ,cabestrillo suburetral ,Stress urinary incontinence ,suburethral sling ,urethra ,urodynamics - Abstract
Objetivo: reflexionar sobre la importancia del diagnóstico de la hipermotilidad uretral en el manejo quirúrgico de la disfunción intrínseca del esfínter uretral y la evaluación que se ha hecho de la hipermotilidad en los estudios que evalúan las diferentes técnicas para su corrección. Conclusión: son pocos los estudios en pacientes con diagnóstico de deficiencia esfinteriana intrínseca que han evaluado la tasa de curación y porcentaje de complicaciones posoperatorias en pacientes llevadas cirugía con cabestrillos TVT y TOT teniendo en cuenta la presencia o no de hipermotilidad uretral. Objective: To reflect on the importance of diagnosing urethral hypermobility in the surgical management of intrinsic urethral sphincter dysfunction, and on the assessment of hypermobility carried out in the studies that have evaluated the different techniques used for addressing the problem. Conclusion: Only a few studies in patients diagnosed with intrinsic sphincter dysfunction have evaluated cure rates and percentage of post-operative complications in patients taken to surgery with TVT and TOT slings, taking into account the presence or absence of urethral hypermobility.
- Published
- 2014
25. Transvestibular Urethrolysis
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Carmignani, G., Varca, V., Alchiede Simonato, Carmignani, Giorgio, Varca, Virginia, Simonato, Alchiede, Carmignani, G, Simonato, A, and Traverso, P
- Subjects
Medical Records Systems, Computerized ,Urinary Incontinence, Stress ,Dissection ,Suburethral tape ,General Medicine ,Urinary Retention ,Urinary Bladder Neck Obstruction ,Urinary incontinence surgery ,Urethrolysi ,Treatment Outcome ,Postoperative Complications ,Urinary Incontinence ,Urethra ,Retrospective Studie ,Urologic Surgical Procedure ,Vagina ,Humans ,Urologic Surgical Procedures ,Female ,Postoperative Complication ,Female urethra ,Urinary Incontinence, Stre ,Retrospective Studies ,Human - Abstract
Bladder outlet obstruction with obstructive and irritative urinary symptoms may be a complication of surgery for female urinary incontinence. In presence of persistent symptoms the therapy is surgical and usually consists in an accurate urethrolysis. The way of approach is generally transvaginal. In this paper we propose and describe our experience with a transvestibular approach.From 1995 to 2009 18 women who had undergone anti-incontinence surgery (TVT 12 pts, TOT 3 pts, Burch retropubic colposuspension 3 pts) with obstruction and/or irritative symptoms underwent to a transvestibular urethrolysys. Five patients had urinary retention the other patients had post voiding residual urine100 ml. With a scalpel blade a circum-meatal incision was performed and the urethra was progressively freed, dissecting just below the os pubis upwards and on the vaginal wall downwards untethering it under direct vision obtaining a complete circular freeing of the urethra; at the end the urethral meatus is repositioned with circular stiches.The operation lasts between 20 and 40 minutes. Urethral catheter was left in place for 24-48 hours and no complications were observed. The post-voiding residual urine decreased in all the cases and the irritative symptoms were reduced.The transvestibular approach represents a safe and effective approach to urethrolysis undependently of the type of anti-incontinence surgey carried out. Urethrolysis has the advantage of working in a relatively unscarred tissue, can allow a complete untethering of the urethra even in the retropubic space and leaves the vaginal wall intact.
- Published
- 2012
26. Tratamiento de la estrechez del meato uretral por balanitis xerótica obliterante: resultados a largo plazo empleando meatoplastia de Malone
- Author
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Treiyer, A., Anheuser, P., Reisch, B., and Steffens, J.
- Subjects
Cirugía reconstructiva ,Pene ,Meatal stenosis ,Urethra ,Reconstructive surgery ,Balanitis xerótica obliterante ,Estenosis de meato uretral ,Uretra ,Lichen sclerosus ,Penis - Abstract
Objetivo: Presentar nuestra experiencia en el tratamiento de estenosis severa localizada en el meato uretral en niños y adultos con balanitis xerótica obliterante. Material y métodos: Un total de 21 pacientes con una edad promedio de 41,7 (7-75) años fueron operados en un período de 5 años utilizando la técnica de meatoplastia según Malone. El seguimiento postoperatorio medio fue 40,8 (6-54) meses. El procedimiento quirúrgico consistió en una pequeña incisión ventral del meato uretral seguida por una meatotomía dorsal profunda, corrigiendo el defecto estético a nivel del glande a través de una sutura en «V» invertida. La evaluación postoperatoria fue realizada en todos los pacientes a través de encuesta escrita que informaba de los resultados funcionales y estéticos de la técnica quirúrgica. Resultados: No se registraron complicaciones postoperatorias, ni tampoco recidiva de la estenosis uretral. Dieciocho pacientes (85,7%) respondieron el cuestionario de evaluación postoperatoria, todos muy satisfechos con el resultado funcional conseguido. Quince de ellos (83,3%) refirieron estar también muy satisfechos con el resultado estético de dicha técnica. Conclusión: La meatoplastia según Malone es una buena alternativa para el tratamiento de la estenosis de meato uretral. Es una técnica fácil, que puede realizarse rápidamente. Evita llevar a cabo un meato hipospádico y consigue buenos resultados postoperatorios. Objective: To present our experience in the treatment of severe stenosis of the external urinary meatus in male children and adults with balanitis xerotic obliterans. Materials and Methods: A total of 21 patients were operated on in a 5-year period, using the meatoplasty technique of Malone. Mean patient age was 41.7 years (range 7-75). Mean postoperative follow-up was 40.8 months (range 6-54). The surgical procedure consisted in making a small ventral incision of the urethral meatus with an extensive dorsal meatotomy, correcting the esthetic defect of the gland with an inverted V-shaped relieving incision. The postoperative evaluation was performed in every patient by written questionnaire informing about the functional and cosmetic results of the surgical technique. Results: No post-surgical complications or recurrences of the urethral stenosis were recorded. A total of 18 patients (85.7%) replied to the post-surgical questionnaire. All were very satisfied with the functional result. Fifteen (83.3%) were also very satisfied with the cosmetic results of the technique. Conclusion: The meatoplasty of Malone is a good alternative for the treatment of urethral meatal stenosis. It is an easy and rapid-to-perform technique. It avoids creating a hypospadiac meatus and achieves good postoperative results.
- Published
- 2011
27. Manejo racional y selectivo de los pacientes con estenosis de uretra anterior
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Gómez, R., Marchetti, P., and Castillo, O.A.
- Subjects
Estenosis uretral ,Urethral Stricture ,Uretrotomía interna ,Urethroplasty ,Urethal stenosis ,Urethra ,Estrechez uretral ,Uretroplastia ,Internal urethrotomy ,Uretra - Abstract
Introducción: El manejo de la estenosis de la uretra anterior es controvertido. Se lleva a cabo un artículo de revisión que pone al día el estado actual del tratamiento quirúrgico de la estenosis de uretra anterior. Material y métodos: Se revisa la experiencia del Hospital del Trabajador en Santiago de Chile respecto a las diferentes modalidades de tratamiento quirúrgico para esta entidad y se revisa la literatura científica al respecto. Resultados: Tradicionalmente la estenosis de uretra anterior se ha tratado con métodos mínimamente invasivos (dilataciones y uretrotomía interna), que no son capaces de curar a más del 30-35% de los pacientes. Por otro lado la cirugía de reconstrucción uretral (uretroplastia) es más compleja y requiere entrenamiento, pero puede curar a la vasta mayoría de los pacientes en un solo procedimiento quirúrgico. Debido a falta de experiencia y entrenamiento en cirugía reconstructiva, existe sobreuso y abuso de los métodos no invasivos, en perjuicio de la calidad de vida de los pacientes. Existe amplia evidencia de que la uretrotomía interna es un excelente método para tratar estenosis de hasta 1cm de longitud, pero su efectividad disminuye drásticamente por encima de 1,5cm. Ahora bien, las estenosis más largas tienen indicación directa de uretroplastia, sobre todo si ya ha fallado una uretrotomía previa. Conclusión: El manejo de este proceso debe ser selectivo, empleando el tratamiento apropiado orientado a curar y no sólo a paliar la enfermedad. Es necesario mejorar el entrenamiento de los urólogos en uretroplastia y/o establecer centros de referencia para poder ofrecer un tratamiento óptimo a cada caso. Introduction: The management of anterior urethral stricture is controversial. A review article was written, which updates the current situation of the surgical treatment of anterior urethral stricture. Materials and methods: The experience of the Hospital del Trabajador in Santiago de Chile regarding its different surgical approaches, as well as scientific literature on the topic, were reviewed. Results: Traditionally, anterior urethral stricture has been treated using minimally invasive techniques (dilatation and internal urethrotomy), which are unable to cure more than 30-35% of patients. On the other hand, urethral reconstruction surgery (urethroplasty) is more complex and requires training, however it can cure a wide majority of patients in a single surgical procedure. Due to a lack of experience and training in reconstructive surgery, non-invasive methods are overused and abused, to the detriment of the patients´ quality of life. There is substantial evidence that internal urethrotomy is an excellent method for treating stricture of up to 1cm in length, however its efficacy decreases drastically above 1.5cm. Notwithstanding, urethroplasty is directly indicated for larger strictures, especially if prior urethrotomy failed. Conclusion: This procedure must be managed selectively, applying the appropriate treatment aimed at curing and not only palliating the disease. Urologists must be better trained in urethroplasty and/or centres of excellence must be established to be able to offer the best treatment in each case.
- Published
- 2011
28. Adenocarcinoma de células claras uretral intradiverticular: Presentación de un nuevo caso en una mujer
- Author
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A. Gené-Heym, A. Pozo-García, M. Cruz-Ruiz, J. Oleza-Simo, and C. Reynes-Sancho
- Subjects
medicine.medical_specialty ,Urethra ,medicine.anatomical_structure ,business.industry ,General surgery ,medicine ,Urology ,Adenocarcinoma ,General Medicine ,Presentation (obstetrics) ,medicine.disease ,business - Published
- 2010
29. Células madre y medicina regenerativa en urología, 2.ª parte: urotelio, vejiga, uretra y próstata
- Author
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J.M. Osca-García, L.M. Moratalla-Charcos, M. Gil-Salom, E. Fornas-Buil, T. Pastor-Navarro, and M. Beamud-Cortés
- Subjects
medicine.medical_specialty ,Células madre ,Urología ,Urology ,Ingeniería tisular ,Stem cells ,Regenerative medicine ,Cell therapy ,Urotelio ,Clinical work ,Medicina regenerativa ,Urethra ,Prostate ,Tissue engeneering ,medicine ,Vejiga urinaria ,Urothelium ,business.industry ,General Medicine ,Urinary bladder+Urethra ,Próstata ,Urinary bladder ,medicine.anatomical_structure ,Terapia celular ,Stem cell ,business ,Uretra - Abstract
Introducción: La investigación en terapia celular y medicina regenerativa, desarrollada en su mayor parte en torno al estudio de las células madre, está obteniendo resultados prometedores en todas las especialidades médicas. En urología están llevándose a cabo grandes avances en este campo, si bien existen ciertas dificultades, pues, por ejemplo, a fecha de hoy aún no ha sido posible la completa identificación y aislamiento de las células madre uroteliales ni prostáticas humanas, aunque muchos grupos se están acercando cada vez más a ello. Material y métodos: Realizamos una búsqueda electrónica mediante la base de datos Pubmed, tanto de artículos originales como de revisiones, utilizando los criterios de búsqueda stem cells urology, urothelial stem cells, bladder stem cells, prostate stem cells, urethra stem cells, cell therapy urology, tissue engeneering urology y regenerative medicine urology. Resultados: Hemos hecho una revisión de 30 trabajos publicados hasta noviembre de 2009, tratando con ello de hacer una recopilación lo más completa posible, para poder conocer un poco mejor los avances realizados en este campo, desde los inicios hasta nuestros días. Conclusión: Aunque existen aún importantes numerosas incógnitas, la mayor de ellas conseguir la identificación, aislamiento y cultivo de las células madre renales, uroteliales y prostáticas humanas, esto no debe impedir a los investigadores el poder trasladar los resultados obtenidos en el laboratorio a la clínica. Introduction: Investigation in cell therapy and regenerative medicine, mainly developed around stem cell research, is reaching promising results in every medical specialities. There are also being great advances in Urology, despite the difficulties researchers are facing, as complete identification and isolation of human urothelial and prostatic stem cells has not been possible yet, although many groups are close to achieve it. Material and methods: We performed an electronic research through the Pubmed database, of both original and review publications, with the following search criteria: "stem cells urology", "urothelial stem cells", "bladder stem cells", "prostate stem cells", "urethra stem cells", "cell therapy urology", "tissue engeneering urology" y "regenerative medicine urology". Results: We reviewed 30 articles published up to November 2009, trying to summarize thoroughly the most relevant findings and the last advances in this fild, from the first steps to this day. Conclusion: Despite the great lack of knowledge existing, especially the need for achieving the identification of kidney, urothelium and prostate stem cells, this shouldn't prevent researchers from translating the laboratory results to the clinical work.
- Published
- 2010
30. ¿Divertículo uretral tras descenso anorectal asistido por laparoscopia (DARAL) en malformacion anorectal: es siempre necesario resecar el diverticulo?
- Author
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López, Pedro José, Guelfand, Miguel, Angel, Lorena, Paulos, Angélica, Cadena, Yair, Escala, José M., Letelier, Nelly, and Zubieta, Ricardo
- Subjects
Laparoscopia ,Malformación anorectal ,Diverticulum ,Complications ,Urethra ,Pediátricos ,Divertículo ,Laparoscopy ,Paediatrics ,Uretra ,Complicaciones ,Anorectal malformations - Abstract
Objetivo: Con el uso cada vez mayor de la cirugía mínimamente invasiva, el divertículo uretral tras la cirugía anorectal se ha convertido en un problema. Los pocos casos descritos se han manejado con extirpación quirúrgica. Nosotros describimos un caso de divertículo uretral tras descenso anorectal asistido por laparoscopía (DARAL) con un resultado exitoso despues de un período de vigilancia activa. Método: Se trata de un paciente de sexo masculino, nacido a término, portador de una malformación anorectal (MAR) alta con fístula recto-prostática fue sometido a una colostomía el primer día de vida. También portador de malformaciones asociadas; reflujo bilateral de bajo grado, riñón en herradura y una hemi-vértebra torácica; sin embargo, sin signos de médula anclada. Se inició profilaxis antibiótica. Resultados: A los 3 meses de edad, fue sometido a un DARAL con un abordaje abdominal de 3 puertos. Despues de la completa disección del intestino distal, la fístula recto-prostática fue identificada y ligada con clips metálicos. Un trocar de 10mm fue insertado a través del centro del complejo es finteriano, que fue previamente identificado bajo visión laparoscópica durante la estimulación eléctrica perineal. El descenso anorectal se llevó a cabo sin tensión. La vejiga permaneció drenada con catéter uretral por 14 días. En el 18º día post-operatorio, una cistografía miccional mostró una imagen diverticular de 15 x 5mm a nivel de la uretra membranosa. Despues de 6 meses, una nueva cistografía miccional mostró una uretra normal sin signos de divertículo ni estenosis; persistencia de reflujo grado 2 a derecha y resolución de reflujo a izquierda. Al año de vida la colostomía fue cerrada sin problemas. Seis meses después, se ha mantenido libre de infección urinaria y su micción es con flujo normal. Conclusión: Este artículo sugiere que el DARAL es un abordaje factible para MAR, aunque el divertículo uretral es una de las principales preocupaciones. Puede evolucionar sin complicaciones, y eventualmente resolverse en forma espontánea. La vigilancia activa puede ser una opción en pacientes asintomáticos seleccionados, sin embargo se recomienda un mayor seguimiento para constituir una mejor evidencia que apoye esta medida. Objectives: With the increased use of minimally invasive surgery, the urethral diverticulum after anorectal surgery has become an issue. The few cases reported have been managed by surgical excision. We hereby report a case of urethral diverticulum after a laparoscopically-assisted anorectal pull-through (LAARP) procedure with a successful outcome after a period of active surveillance. Methods: A full-term boy who displayed a high ano-rectal malformation (ARM) and a recto-prostatic fistula underwent colostomy on the first day. He also showed associated malformations: bilateral low-grade reflux, horseshoe kidney and thoracic hemivertebrae; however, there were no signs of spinal cord tethering. Antimicrobial prophylaxis was started. Results: At the age of 3 months, he underwent a LAARP with a 3 abdominal-port approach. After complete dissection of the distal bowel, the recto-prostatic fistula was identified and tied with metallic clips. A 10 mm trocar was inserted through the centre of the sphincteric complex, which had been previously identified under laparoscopic view during perineal electrical stimulation. The anorectal pull-through was accomplished without tension. The bladder remained stented for 14 days. On the 18th postoperative day, a voiding cystourethrogram (VCUG) showed a 15 X 5 mm image of the diverticulum at the level of the membranous urethra. After 6 months, a new VCUG showed a normal urethra with neither signs of the diverticulum nor strictures; persistence of grade 2 reflux on the right side and resolution of the reflux on the left. When the boy was one year old his colostomy was closed uneventfully. Six months later he had not come into the emergency since the operation and voided with a normal flow. Conclusion: This report suggests that LAARP is a feasible approach for ARM, although urethral diverticulum is a major concern. It may evolve without complications, and eventually resolve spontaneously. Active surveillance might be an option in selected asymptomatic patients; however a longer follow-up is advised to constitute better evidence supporting that policy.
- Published
- 2010
31. Experiencia clinica en el manejo de fracturas de pene en el Hospital Universitario del Valle (Cali-Colombia)
- Author
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Restrepo, Jaime Alejandro, Gonzalo Estrada, Carlos, Andres García, Herney, and Carbonell, Jorge
- Subjects
Corpora cavernosa ,Pene ,Urethra ,Penile fracture ,Fractura de pene ,Cuerpos cavernosos ,Uretra ,Penis - Abstract
Objetivo: El objetivo principal del presente estudio fue describir las características clínicas de los pacientes con diagnóstico de fractura de pene en el Hospital Universitario del Valle (Cali, Colombia). Métodos: Se realizó un estudio descriptivo, en el que se revisaron todas las historias clínicas de los pacientes con diagnóstico de fractura de pene entre enero de 2001 a diciembre de 2008 en el Hospital Universitario del Valle (HUV) en la ciudad de Cali. Se tuvieron en cuenta variables relacionadas con los antecedentes urológicos, la etiología, el diagnóstico de la fractura, el procedimiento quirúrgico y el seguimiento. Se realizó un análisis univariado con el programa estadístico STATA v. 10.1 Resultados: Se encontraron 18 casos de fractura de pene con un promedio de edad de 30 años. 11 pacientes (61%) presentaron el episodio secundario a la relación sexual. Se presentó edema, dolor y chasquido más frecuentemente. El diagnóstico fue clínico en el 100% de los casos. El abordaje quirúrgico se realizó con una incisión circunferencial en la mayoría de los pacientes. El cuerpo cavernoso derecho fue el más frecuentemente lesionado y en la mayoría de los casos la lesión fue corregida con una sutura absorbible de forma continua. Los pacientes tuvieron una hospitalización posquirúrgica en promedio de 1.5 días. Conclusiones: La fractura de pene es una entidad cuyo diagnóstico es clínico, debe realizarse de forma precoz y la reparación quirúrgica es el tratamiento de elección para evitar complicaciones y permitir que el paciente retorne a su actividad sexual satisfactoria de manera temprana. Objectives: The main objective of this study was to describe the clinical characteristics of patients diagnosed with penile fracture in the Hospital Universitario del Valle (Cali, Colombia). Methods: A descriptive study, reviewing all the medical records of patientsdiagnosed with penile fracture from January 2001 to December 2008 at Hospital Universitario del Valle (HUV) in Cali. It took into account variables related to urological history, etiology, diagnosis, the surgical treatment and follow-up. Univariate analysis was performed with the statistical program STATA v. 10.1 Results: There were 18 cases of penile fracture with an average age of 30 years. 11 patients (61%) had episodes related to intercourse. Patients presented swelling, pain and popping or cracking sound. The diagnosis was done by history and physical examination in 100%. Surgery was performed with a subcoronal incision in most of the patients. The right corpus cavernosum was frequently injured and corrected with absorbable suture. The patients had an average of 1.5 days of postoperative hospital stay. Conclusions: Penile fracture is an entity the diagnosis of which is straightforward and can be reliable by history and physical examination. Surgical repair is the treatment of choice preventing complications, allowing the patient to return to satisfactory sexual life.
- Published
- 2010
32. Leiomioma de uretra masculina: Aportación de un caso y revisión de la literatura
- Author
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Garrido Abad, Pablo, Fernández Arjona, Manuel, Herranz Fernández, Luis Miguel, Muñoz-Delgado Salmerón, Jerónimo, and Capote, Luis Felipe
- Subjects
Leiomyoma ,Urethra ,Tracto urinario bajo ,Leiomioma ,Lower urinary tract ,Uretra - Abstract
Objetivos: Aportamos un nuevo caso de leiomioma uretral (LU) de 5 cm. en un paciente varón de 34 años. Método: Es extraordinariamente infrecuente en uretra masculina con tan sólo siete casos descritos en la literatura mundial con anterioridad. La etiología de esta neoplasia benigna es desconocida. Los leiomiomas pueden presentarse en diversas localizaciones dentro del tracto urinario. Cuando aparece en uretra, se puede comportar de forma asintomática, si bien es más frecuente su asociación a sintomatología obstructiva. Su diagnóstico definitivo requiere de confirmación histopatológica. Dentro del diagnóstico diferencial debemos incluir otras neoplasias intrauretrales. Resultado: Paciente libre de sintomatología obstructiva del tracto urinario inferior tras abordaje quirúrgico endoscópico del LU. Conclusiones: La indicacíon y el abordaje quirúrgico dependerán de la localización y el tamaño del tumor. Su pronóstico es excelente tras su excisión quirúrgica. Objectives: Case report of a 5 cm. male urethral leiomyoma (UL). Method: UL is extremely rare entity, with only seven cases in the literature. Its etiology is still unknown. Leiomyoma may be present in several locations inside the urinary tract. When located in the urethra it usually produces obstructive symptoms, but also may have asymptomatic behavior. Definitive diagnosis requires histological confirmation. Intraurethral neoplasms must be included in the differential diagnosis. Results: Patient is free of lower urinary tract symptoms after complete excision of his urethral leiomyoma. Conclusions: Indication and surgical approach depend on tumor and size location. Prognostic is excellent after surgical removal.
- Published
- 2010
33. Muscle-derived stem cell therapy for stress urinary incontinence
- Author
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Á. R. Proaño, Andrés Medrano, Osvaldo Mazza, and Gustavo Garrido
- Subjects
Male ,medicine.medical_specialty ,Urinary effort incontinence ,Urinary system ,Biopsy ,Urinary Incontinence, Stress ,Urology ,Urinary incontinence ,Cell Separation ,Transplantation, Autologous ,Myoblasts ,Medicine ,Humans ,Rhabdosphincter ,Muscle, Skeletal ,Cells, Cultured ,Randomized Controlled Trials as Topic ,Ultrasonography ,Clinical Trials as Topic ,business.industry ,Urethral sphincter ,Multipotent Stem Cells ,Células madre derivadas de músculo ,General Medicine ,Transurethral ultrasound ,Fibroblasts ,Surgery ,Transplantation ,Adult Stem Cells ,medicine.anatomical_structure ,Urethra ,Treatment Outcome ,Sphincter ,Urologic Surgical Procedures ,Incontinencia urinaria de esfuerzo ,Female ,Muscle-derived stem cells ,Stem cell ,medicine.symptom ,business ,Rabdoesfínter ,Ultrasonido transuretral - Abstract
El conocimiento de la incontinencia urinaria de esfuerzo (IUE) se ha incrementado, dando como resultado una amplia gama de diferentes opciones terapéuticas disponibles. La uretra media y el esfínter uretral externo son ahora el eje en el manejo de la IUE. La terapia con células madre para la regeneración del esfínter deficiente ha sido motivo de investigaciones novedosas. Obteniendo mioblastos y fibroblastos autólogos de biopsias musculares esqueléticas, cultivándolas e implantándolas después de su diferenciación en el esfínter uretral externo se advierte un nuevo concepto en el tratamiento de la incontinencia de esfuerzo. En lugar de utilizar materiales heterólogos, tales como mallas sintéticas (slings) o sustancias de abultamiento (colágeno, siliconas, etc.), ahora tenemos el potencial para restaurar la función con el uso de células madre autólogas. The knowledge of the urinary effort incontinence (UEI) has increased, giving like result an ample range of different therapeutic options available. The middle urethra and external urethral sphincter are the focus in management of UEI. Stem cells therapy for the regenerative repair of the deficient sphincter has been the leading research of incontinence. Obtaining autologous myoblasts and fibroblasts of skeletal muscle-biopsies, cultivating them and transplanting them after its differentiation, into the external urethral sphincter it warns a new concept in the treatment of the incontinence. Instead of using heterologous materials such as synthetic mesh (slings) or bulking agents (collagen, silicone, etc); we now have the potential to restore function with the use of autologous stem cells.
- Published
- 2010
34. Radical cystectomy in patients with non-muscle invasive bladder cancer who fail BCG therapy
- Author
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S. Sabaté, Juan Palou, Jorge Huguet, Humberto Villavicencio, and Josep M Gaya
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Biopsy ,Urology ,Kaplan-Meier Estimate ,Cistectomía ,Cystectomy ,Urethra ,Prostate ,medicine ,Carcinoma ,Humans ,Neoplasm Invasiveness ,BCG ,Stage (cooking) ,Pathological ,Aged ,Retrospective Studies ,Carcinoma, Transitional Cell ,Bladder cancer ,medicine.diagnostic_test ,business.industry ,Retrospective cohort study ,General Medicine ,Middle Aged ,medicine.disease ,medicine.anatomical_structure ,Treatment Outcome ,Urinary Bladder Neoplasms ,Drug Resistance, Neoplasm ,Cáncer de vejiga ,BCG Vaccine ,Disease Progression ,Female ,Neoplasm Recurrence, Local ,business - Abstract
Objetivos: evaluar las características y evolución de los pacientes con tumores vesicales no músculo-infiltrantes (TVNMI) sometidos a cistectomía radical por fracaso a la terapia con bacilo de Calmette-Guérin (BCG). Material y métodos: de 864 cistectomías radicales (CR) realizadas en nuestro centro entre 1989 y 2002, 95 (11%) se indicaron en pacientes que habían recibido tratamiento previo con BCG. En 62 casos (65,2%) la CR se realizó por presencia de TVNMI recidivado de alto grado o carcinoma in situ, a pesar del tratamiento con BCG. En 17 de ellos (27%) la pieza de cistectomía mostró un estadio > pT2. Se consideró que estos pacientes fueron infraestadiados. En 33 casos (34,7%) la CR se hizo por progresión clínica a enfermedad músculo-infiltrante (> T2) durante el seguimiento. Analizamos las características y evolución de los pacientes cistectomizados por fracaso a la terapia con BCG y si existían diferencias entre los infraestadiados y los que presentaron progresión clínica durante el seguimiento. Resultados: la supervivencia cáncer-específica a los 5 años fue del 90% en los 45 casos con estadio clínico y patológico de TVNMI, y del 50,6% en los 50 pacientes con progresión a enfermedad músculo-infiltrante (progresión clínica e infraestadiados) (p < 0,05). No hubo diferencias en la supervivencia entre los pacientes infraestadiados y con progresión clínica. La mediana de tiempo entre el diagnóstico del tumor y la progresión fue de 24 meses (percentil 10-90; 6-98 meses).Los pacientes con progresión clínica presentaron de forma significativa mayor proporción de tumores T1 (p = 0,015) en la RTU previa a la progresión y más pT3 (p < 0,01) en pieza de CR. Los pacientes infraestadiados tuvieron más estadios patológicos pT4 (p < 0,02). Conclusiones: en TVNMI de alto riesgo que fracasan a la BCG, la CR debe realizarse antes de la progresión a tumor músculo-infiltrante. Los T1 de alto grado son responsables de la mayor parte de progresiones clínicas y tempranas. Ciertos TVNMI pueden presentar progresión subclínica a través de la próstata. Objective: to assess the characteristics and outcomes of patients with non-muscle invasive bladder cancer (NMIBC) undergoing radical cystectomy (RC) due to BCG failure. Materials and methods: ninety-five (11%) of the 864 patients undergoing radical cystectomy (RC) at our center from 1989 to 2002 had received prior treatment with BCG. Of these, 62 (65.2%) underwent RC due to relapsing, high-risk NMIBC or CIS despite BCG therapy. A stage > pT2 tumor was reported in the cystectomy specimen in 17 (27%) of these patients, who were considered to have been understaged. RC was performed for clinical progression in 33 patients (34.7%). Their last transurethral resection before RC showed invasive disease. A retrospective analysis was made of the outcomes of patients who underwent RC for BCG failure and the clinical and pathological differences between understaged patients and those with clinical progression. Results: five-year CSS was 90% in 45 patients with clinical and pathological NMIBC and 50.6% in 50 patients with progression to muscle-infiltrating disease (clinical progresion and understaged) (p < 0,05). There were no differences in survival in patients with clinical progresion as compared to understaged patients. Median time from tumor diagnosis to tumor progresion was 24 months (10th-90th percentile, 6-98 months). Patients with clinical progresion had significantly more T1 tumors (p = 0.015) in TUR before progression and more pT3 tumors (p < 0.01) in the RC specimen. Understaged patients more often had pathological pT4 stages (p < 0.02). Conclusion: in patients with high-risk NMIBCs who fail BCG therapy, RC should be performed before progression because survival is decreased when the RC specimen shows muscle-invasive disease. High-grade T1 tumors are responsible for most early clinical progressions. Patients with NMIBC may have subclinical progression, mainly within the prostate.
- Published
- 2010
35. Prolapso uretral: un diagnóstico diferencial del abuso sexual en niños
- Author
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Montes, G.A., García, H.A., and Pataquiva, M.E.
- Subjects
uretra ,trauma ,urethral prolapse ,prolapso uretral ,prolapso ,abuso sexual ,sexual abuse ,urethra ,prolapse - Abstract
Objetivo: Describir el caso de una paciente con prolapso uretral que consultó por sospecha de trauma genital no accidental (abuso sexual) y realizar una revisión de la literatura. Material y métodos: Se describió el caso clínico de un paciente con prolapso uretral quien fue llevado por la autoridad para examen sexológico forense ante el Instituto Nacional de Medicina Legal y Ciencias Forenses de Bogotá - Colombia, por sospecha de abuso sexual. Posteriormente se realizó una búsqueda exhaustiva de la literatura en diferentes bases de datos con las que se sustentó la discusión del caso. Resultados: Se presentó el caso de una paciente de 23 meses de edad con historia de sangrado vaginal con sospecha de trauma genital, abuso sexual y maltrato infantil que después de ser evaluada adecuadamente por especialistas en el área genital y con examen riguroso bajo sedación se hizo un diagnóstico de prolapso uretral y fue atendida y manejada para tal fin. Conclusiones: El concepto de un médico especialista forense es de gran importancia dentro del proceso judicial en un delito sexual, por esta razón el examen sexológico forense requiere de una gran rigurosidad que permita llegar a un diagnóstico acertado y no deben olvidarse los diagnósticos diferenciales en estos pacientes para hacer un manejo adecuado tanto médico como judicial. Purpose: To describe the case of a patient with urethral prolapse who consulted for suspected non-accidental genital trauma (sexual abuse) and to review the literature. Materials and methods: It was described the case of a patient with urethral prolapse who was taken by the authorities for forensic sexological examination at National Institute of Legal Medicine and Forensic Sciences in Bogota- Colombia on suspicion of sexual abuse. Subsequently conducted a thorough literature search in different databases that support the discussion of the case. Results: It is presented the case of a 23-month-old girl with a history of vaginal bleeding with suspected genital trauma, sexual abuse and child abuse after being thoroughly assessed by experts in the genital area and rigorous examination under sedation was diagnosed urethral prolapse and was treated and managed for that purpose. Conclusions: The concept of a forensic medical specialist is of great importance in the judicial process in a sexual offense, which is why forensic sexological examination requires a high standard that will lead to a correct diagnosis and should not miss the differential diagnosis in these patients to properly manage both medical and legal.
- Published
- 2009
36. Cuerpos extraños en pene
- Author
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Pastor Navarro, Héctor, Donáte Moreno, María José, Carríón López, Pedro, Segura Martín, Miguel, Lorenzo Romero, Juan Gabriel, Pastor Guzmán, José María, Payá Berbegal, J., Lujan Marco, Saturnino, and Virseda Rodríguez, Julio
- Subjects
Foreign body ,Pene ,Urethra ,Cuerpo extraño ,Uretra ,Penile - Abstract
Objetivo: Mostrar 8 casos de cuerpos extraños en pene. Métodos/Resultados: Realizamos una presentación fundamentalmente visual de variados artilugios o cuerpos extraños de ubicación peneana. Conclusiones: Raramente la existencia de cuerpos extraños peneanos se debe a accidentes. Los cuerpos extraños en pene son colocados por muy diversas razones, destacando principalmente dentro de actividades eróticas o autoeróticas, pudiendo tener consecuencias desde leves, a casos en los que puede acabar en amputación peneana. Objective: To describe 8 cases of penile foreign bodies. Methods/Results: We provide an essentially visual overview of various objects or foreign bodies affecting the penis. Conclusions: The presence of penile foreign bodies is rarely due to an accident. These objects are placed for a wide variety of reasons, but primarily for erotic or self-arousal purposes. The consequences of penile foreign bodies can be mild or very severe, resulting in penile amputation.
- Published
- 2009
37. Uretroplastia con mucosa oral en estenosis de uretra anterior
- Author
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Roca Edreira, A., Aguilera Tubet, C., García-Montesinos Perea, B.M., García Montesinos, M., and Hernández Rodríguez, R.
- Subjects
Mucosa oral ,Urethra ,Buccal mucosa ,Uretra ,Stricture ,Estenosis - Abstract
Los injertos de mucosa oral pueden ser utilizados para la reparación satisfactoria de estenosis de uretra péndula y bulbar. Material y métodos: Presentamos nuestra experiencia con injertos de mucosa oral en 8 pacientes. La longitud del injerto fue entre 4 y 16 cm. Se han realizado tres uretroplastias en uretra péndula, dos en uretra bulbar y tres panuretrales. El seguimiento ha sido entre 36 y 60 meses. Resultados: No se han observado recurrencias. Un paciente refirió parestesias en el labio inferior durante seis meses. Buccal mucosal graft can be used for succesfull repair in both pendulous and bulbar strictures. Material and methods: We present our experience with buccal mucosal graft repair in 8 patients with onlay patch that varies from 4 to 16 cm. in length. Three pendulous, two bulbar and three panurethral strictures were repaired. These patients were observed for 36 to 60 months. Results: No stricture recurrences were observed. Only one patient had lower lip paresthesia for six months.
- Published
- 2008
38. Seno prepúbico congénito: A propósito de un caso
- Author
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Suárez Filippin, P., Ortiz Rodríguez, F., López Tosoni, M.I., Álvarez Portela, P., Brzezinski Niedzwiecki, M., and Sanguinetti Baun, H.
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Congenital ,Urethra ,Duplication ,Prepubic sinus ,Congénito ,Seno prepúbico ,Duplicación ,Uretra - Abstract
El seno prepúbico congénito es un tipo de duplicación uretral poco frecuente, de etiología desconocida. Se han propuesto distintas teorías embriológicas, como así también diversas clasificaciones. La mayoría de los casos se diagnostican en la infancia, la cistouretrografía retrógrada y miccional es el estudio fundamental, tanto para confirmar el diagnóstico como para establecer el tipo de anomalía y la mejor opción terapéutica. Presentamos un caso de seno prepúbico congénito en un varón de 39 años de edad, diagnosticado por secreción purulenta a nivel de un meato accesorio en base del pene. The prepubic congenital sinus is a rare type of urethral duplication of unknown origin. Different embryological theories and classifications has been proposed. Most cases are diagnosed during childhood. The Retrograde Urethrocystography is very important as it determines the diagnosis and helps choosing the best treatment option. We present a case of a prepubic congenital sinus in a 39 years old male who presented with purulent discharge from an accessory meatus in the base of the penis.
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- 2008
39. La meatoplastia dorsal para el tratamiento de la estenosis de meato en pacientes con balanitis xerótica obliterante
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Navalón Verdejo, Pedro, Pallás Costa, Yoni, Juan Escudero, Joaquín, Fabuel Deltoro, Milagros, Ordoño Domínguez, Felipe, Monllor Peidro, Elisa, Ramos de Campos, Macarena, and Ramada Benlloch, Francisco
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Liquen escleroso y atrófico ,Pene ,Urethra ,Balanitis ,Sclerous athropic liquen ,Uretra ,Penis - Abstract
Objetivo: Poner de manifiesto nuestra experiencia en el tratamiento de la estenosis de meato secundaria a balanitis xerótica obliterante mediante la técnica de meatoplastia dorsal. Métodos: Hemos realizado meatoplastia dorsal a 15 pacientes afectos de estenosis de meato balánico secundaria a liquen escleroso y atrófico. Todos los casos fueron intervenidos bajo anestesia local realizando plastia mediante incisión en V invertida según la técnica original de Malone. Resultados: En todos los pacientes intervenidos se objetivó una mejoría flujométrica así como un excelente resultado estético y escasa incidencia de micción dispersa, existiendo un elevado índice de satisfacción evaluado mediante la realización de un cuestionario. Conclusiones: La meatoplastia dorsal con incisión en V invertida es una técnica de fácil ejecución, que permite ser realizada bajo anestesia local, evita la aparición de hipospadias postoperatorio y proporciona excelentes resultados estéticos y funcionales con un bajo índice de recidivas, por lo que consideramos que debe de incluirse en la cartera de procedimientos habituales del urólogo. Objectives: To present our experience in the treatment of meatal stenosis secondary to balanitis xerotica obliterans with the dorsal meatoplasty technique. Methods: We have performed dorsal meatoplasty in 15 patients suffering stenosis of the penile meatus secondary to balanitis xerotica obliterans. All cases were performed under local anesthesia, using an inverted V incision plasty following the original of technique from Malone. Results: All patients showed an improvement in uroflowmetry as well as an excellent aesthetic result, with low incidence of scattered urinary stream; there was a high satisfaction index evaluated by a questionnaire. Conclusiones: Dorsal meatoplasty with inverted V incision is an easy-to-perform technique, which may be done under local anesthesia, avoids the development of post-operative hypospadias, and achieves excellent aesthetic and functional results with a low recurrence rate; therefore we consider it should be included in the list of frequently performed procedures of the urologist.
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- 2007
40. Divertículos uretrales: Revisión de nuestra casuística y de la literatura
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Ramírez Backhaus, M., Trassierra Villa, M., Broseta Rico, E., Gimeno Argente, V., Arlandis Guzmán, S., Alonso Gorrea, M., and Jiménez Cruz, J.F.
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Treatment ,Diverticulum ,Urethra ,Tratamiento ,Divertículo ,Uretra - Abstract
Objetivo: Se valoran los posibles factores etiopatogénicos y se describen la clínica, métodos diagnósticos, abordaje quirúrgico, resultados y complicaciones del manejo de los divertículos uretrales. Material y métodos: Se realizó una revisión retrospectiva de las historias clínicas con diagnóstico de divertículo uretral en el periodo 1986-2006. Resultados: Durante estos 20 años se han tratado un total de 19 pacientes con esta patología: 15 mujeres y 4 hombres. Cinco de las mujeres debutaron clínicamente con sensación de masa vaginal; el resto fueron diagnosticadas en el contexto de un síndrome miccional, incontinencia urinaria o infección urinaria. En el caso de los varones, 3 de ellos presentaron una tumoración palpable en el pene. La prueba diagnóstica más utilizada fue la uretrocistografía miccional seriada; la uretrografía con sonda de doble balón se utilizó en 5 ocasiones y la uretroscopia en 4 pacientes. En los casos más complejos se utilizaron otras técnicas de diagnóstico por la imagen, como la resonancia magnética nuclear. El tratamiento fue la extirpación del divertículo en todos los pacientes, excepto en una mujer que rechazó la intervención. La evolución de las pacientes ha sido satisfactoria realizándose controles periódicos hasta dos años después de la intervención. Dos de los casos, en varones, tuvieron recidivas complejas. Conclusiones: Los divertículos uretrales son una entidad nosológica de difícil diagnóstico dada su baja prevalencia y su clínica inespecífica lo que motiva que, en algunas ocasiones, el diagnóstico sea incidental. La etiopatogenia es adquirida en la mayoría de los casos y su tratamiento quirúrgico, con peores resultados en los hombres debido, probablemente, a que los divertículos se producen en uretras con antecedentes de cirugías previas, manipulación endourológica o lesiones asociadas. Purpose: The possible etiopathogenic factors, symptoms, diagnostic methods, surgical management and complications of the urethral diverticula are reviewed. Materials and methods: A retrospective study of the clinical charts with urethral diverticula diagnosis during the period 1986-2006 was carried out. Results: In the last 20 years a total of 19 patients have been treated for this pathology: 15 females and 4 males. Five of the females started with a sensation of vaginal mass; the rest were diagnosed of micturitional (irritative) syndrome, urinary incontinence or urinary infection. In the case of males, 3 of them had a palpable tumour in the penis. The most used diagnostic method was retrograde and voiding cystourethrography; urethrography with double-occlusion balloon catheter was used in 5 cases and urethroscopy in 4 patients; other techniques of image diagnosis like magnetic resonance imaging were necessary for the most complex cases. The treatment was the excision of the diverticulum, except for one of the females who rejected the treatment. The evolution in all treated women was successful, according to follow up 2 years after the treatment. In males, two of them had complex recurrent diverticula. Conclusions: Urethral diverticula are nosologic entities of difficult diagnosis, due to their low prevalence and their unspecific clinic, therefore diagnosis is sometimes incidental. The etiopathogenity is acquired in most cases and its surgical treatment is more challenging in males than in females probably linked to the fact that diverticula appear in urethras with previous surgery, endourologic manipulation or associated injuries.
- Published
- 2007
41. Amiloidosis primaria localizada en glande peneano: Caso clínico y revisión de la literatura
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Domínguez Domínguez, M., Valero Puerta, J.A., Jiménez Leiro, J.F., Martínez Ruiz, R., and Medina Pérez, M.
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Pene ,Amiloidosis ,Glande ,Urethra ,Glands ,Genitourinary ,Amyloidosis ,Uretra ,Tracto urinario ,Penis - Abstract
La amiloidosis primaria del tracto genitourinario es rara siendo aún más excepcional la afectación única del glande. Generalmente la clínica apunta al diagnóstico de carcinoma de pene y es el examen histológico el que indicará definitivamente el diagnóstico. La Biopsia de la lesión revela depósitos dérmicos de material amorfo eosinofílico. Se presenta el caso de un paciente con amiloidosis primaria en glande. Se realiza revisión de la literatura y se analizan las diferentes actitudes diagnósticas y terapéuticas. Éste es el séptimo caso de amiloidosis primaria localizada en glande descrito en la literatura. Primary localized amyloidosis urinary tract is rare. Localized amyloidosid only glands is a very rare entity. The clinical impression may resemble neoplastic disease but the diagnosis is confirmed by histochemical study. Biopsy of the lesion revealed dermal deposits of amorphous eosinophilic material. A case of patient with primary amyldosis of glands penis is reported. The literature is reviewed and the diagnostic and therapeutic options are discussed. This is the seventh reported case of localized amyloidosis of the glands penis.
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- 2007
42. Fractura de pene con rotura asociada de uretra
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Llarena Ibarguren, Roberto, Villafruela Mateos, Ainara, Azurmendi Arin, Igor, García Fernández, Jorge, and Pertusa Peña, Carlos
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Corpus cavernosum ,Urethra ,Albugínea ,Albuginea ,Cuerpo cavernoso ,Penile fracture ,Fractura de pene ,Uretra - Abstract
Objetivo: Presentamos dos casos de fractura de pene, 1 con fractura asociada de cuerpo esponjoso y sección completa de uretra y otro que sufrió la segunda fractura cavernosa 3 años después de la primera. Métodos: El primer paciente, de 32 años, sufrió la fractura del cuerpo cavernoso derecho durante el coito, 3 años después de haber sufrido una primera fractura de la que fue intervenido de urgencia. En este caso también fue intervenido de inmediato evidenciando la lesión y reparándola, con buenos resultados funcionales. El segundo paciente, de 29 años, sufrió la fractura transversal de ambos cuerpos cavernosos a nivel basal asociándose la sección completa de la uretra en una misma línea de fractura. Intervenido de urgencia se solucionaron todas las lesiones, con buenos resultados estéticos y funcionales. Resultados: Dentro de la rareza que supone la lesión peneana traumática con fractura cavernosa, la asociación de lesión uretral supone una excepción, así como la posibilidad de sufrir una segunda fractura años después de la primera. Conclusiones: La fractura peneana supone una rara urgencia que debe ser reparada de forma inmediata evacuando el hematoma, suturando la lesión albugínea y solucionando la lesión uretral en los raros casos en que se asocie. Los resultados serán mejores, evitándose complicaciones a medio y largo plazo. Objective: We report two cases of penile fracture; one case with associated rupture of the corpus spongiosum and complete urethral section, and the other presenting a second cavernous fracture three years after a first episode. Methods: The first patient, 32 years old, suffered the fracture of the right corpus cavernosum during intercourse three years after a first fracture requiring surgical repair. This time he also underwent surgery immediately to find and repair the lesion, with good functional outcome. The second patient, 29 years old, suffered a transverse fracture at the bases of both corpora cavernosa associated with complete section of the urethra. He underwent emergency surgery to repair all lesions with good esthetic and functional results. Results: Traumatic lesions of the penis with fracture of the corpora cavernosa are rare and the association with urethral rupture is exceptional, as well as it is the possibility of second fracture years after a first episode. Conclusions: Penile fracture is a rare reason for consultation in the emergency setting, which should be repaired immediately with evacuation of the hematoma, closure of the albuginea’s lesion and repair of the urethral lesions when they appear. Results are better, avoiding mid and long-term complications.
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- 2006
43. Quiste prauretral de la glándula de Llitré: un caso excepcional
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Bujons, Anna, Ponce de León, X., Baez, Carlos, Gausa, Lluis, Montlleó, M., Caparrós, Joan, and Villavicencio, Humberto
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Glándula de littré ,Urethra ,Littre's gland ,Paraurethral cyst ,Quiste parauretral ,Uretra - Abstract
Objetivo: Describir un caso clínico de un quiste parauretral en un varón, a nivel de uretra peneana subglandar, patología extremadamente infrecuente. Método/resultado: Paciente varón de 46 años de edad diagnosticado de un quiste parauretral de la glándula de littré, su diagnóstico y posterior tratamiento. Conclusión: Los quistes parauretrales de origen no traumático son muy raros, sólo se han en la literatura,un quiste localizado en ángulo penoescrotal dependiendo de cuerpo esponjoso sin conexión con la uretra y otro caso de inflamación de las glándulas periuretrales de Littré simulando un tumor. Objective: To report one case of paraurethral cyst in the male, located in the subglandular penile urethra, an extremely rare pathology. Methods/results: 46-years-old male patient with the diagnosis of Littre's gland paraurethral cyst. Diagnosis and subsequent treatment. Conclusions: Paraurethral cysts of non traumatic origin are very rare, only two cases are described in the literature, one cyst located at the penoscrotal angle dependent from the corpus spongiosum without connection to the urethra, and another case of in?ammation of the periurethral Littre's glands simulating a tumor.
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- 2006
44. Experiencia de Pittsburgh con la toxina botulínica A inyectable
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Miguel, F. de and Chancellor, M.B.
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Urethra ,Bladder ,Toxina botulínica A ,Prostate ,Vejiga ,Botulinum toxin A ,Lower urinary tract ,Próstata ,Tracto urinario inferior ,Uretra - Abstract
Presentamos la experiencia de un centro durante 6 años con el uso de la toxina botulínica A (TBON-A) en la vejiga, o en la uretra en 110 pacientes, con diversos trastornos del tracto urinario inferior. Se inyectó a 110 pacientes (edad 19-82 años) TBON-A en la vejiga (n = 42) o la uretra (n = 68), 35 V, 75 M. Entre los trastornos de la micción figuraban hiperactividad neurógena del detrusor y/o disinergia detrusor-esfínter, vejiga hiperactiva (VHA), hiperplasia benigna de próstata (HBP), obstrucción del cuello de la vejiga (OCV) y cistitis intersticial (CI). Hasta ahora, 27 pacientes han recibido varias inyecciones (hasta un máximo de 6) a intervalos de > 6 meses. Todos los pacientes que recibieron inyecciones de TBON-A en la vejiga presentaban signos preoperatorios de contracciones involuntarias del detrusor en los estudios urodinámicos. El análisis de los 110 pacientes indica que en el 67,3% la incontinencia disminuyó o desapareció con el tratamiento. Los diarios indican que los síntomas diurnos y nocturnos de la micción disminuyeron. TBON-A fue eficaz a los 7 días y su eficacia se mantuvo durante al menos 6 meses. Las puntuaciones de síntomas en los análisis de CdV, las puntuaciones de síntomas específicos de la enfermedad también mejoraron. No ha habido complicaciones a largo plazo. En dos mujeres con esclerosis múltiple (EM) e incontinencia urinaria leve por estrés en el periodo basal, la pérdida de orina por estrés aumentó tras la inyección de TBON-A en el esfínter externo. En una mujer con EM que recibió una inyección en la vejiga, el volumen de orina residual aumentó de 78 a 155 ml. La paciente no tuvo que someterse a sondaje intermitente. La inyección de TBON-A es una modalidad de tratamiento segura y prometedora para diversos trastornos del tracto urinario inferior tanto del músculo esquelético como del músculo liso. En la serie de pacientes estudiados, TBON-A es igual de eficaz en mujeres que en varones. Las inyecciones de TBON-A en la vejiga son eficaces no sólo para la hiperactividad neurógena del detrusor, sino también para la vejiga hiperactiva. El uso de TBON-A puede incluso considerarse para la CI. We report one institution's six-year experience using botulinum toxin A (BONT-A) in the bladder and urethra in 110 patients for a variety of lower urinary tract dysfunction. 110 patients (age 19-82) were injected with BONT-A into the bladder (n=42) or urethra (n=68), 35 M, 75 F. Voiding dysfunction included: neurogenic detrusor overactivity and/or detrusor sphincter dyssynergia, overactive bladder (OAB), benign prostatic hyperplasia (BPH), bladder neck obstruction (BNO) and interstitial cystitis (IC). Currently, 27 patients have undergone further injections (up to 6) at intervals > 6 months. All the patients with bladder BONT-A injection had preoperative evidence of involuntary detrusor contractions during urodynamic testing. Analysis of the 110 patients indicates that 67.3% reported a decrease or absence of incontinence. Diaries indicate a decrease in both day and night voiding symptoms. Efficacy occurred within 7 days and lasted for at least 6 months. Condition specific QOL symptom scores also demonstrated improvement. There have been no long-term complications. Two MS women with mild baseline stress urinary incontinence reported increased leakage with stress after BONT-A external sphincter injection. One MS woman who had a bladder injection had an increased residual urine from 78 to 155 ml. She did not have to perform intermittent catheterization. BONT-A injection is a safe and promising treatment modality for a variety of lower urinary tract dysfunctions for both skeletal and smooth muscle dysfunction. In our series, BONT-A is equally effective in women as it is in men. Bladder injections with BONT-A are effective for not only neurogenic detrusor overactivity but also overactive bladder. BONT-A can even be considered for IC.
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- 2006
45. CIRUGÍA MÍNIMAMENTE INVASIVA EN EL TRATAMIENTO DE LA INCONTINENCIA URINARIA FEMENINA DE ESFUERZO: TVT-O
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Vicente Solà D, Paolo Ricci A, Jack Pardo S, Enrique Guiloff F, and Humberto Chiang M
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medicine.medical_specialty ,Intraoperative Complication ,urinary incontinence ,Urinary retention ,business.industry ,incontinencia de orina ,Obstetrics and Gynecology ,Urinary incontinence ,Vaginal wall ,Surgery ,Cirugía mínimamente invasiva ,Urethra ,medicine.anatomical_structure ,Minimal invasive surgery ,Ambulatory ,medicine ,Operating time ,Operative time ,medicine.symptom ,business ,TVT-O - Abstract
Objetivo: Analizar nuestra experiencia en la aplicación de TVT-O, en la corrección quirúrgica de la incontinencia de orina de esfuerzo (IOE). Pacientes y Método: Seguimiento prospectivo de 135 pacientes sometidos a TVT-O en Clínica Las Condes. Resultados: La mediana de edad fue de 55 años (R: 38 a 74 años), IMC 27,5 (R: 23 a 34) y paridad vaginal 2 (R: 0 a 5). Mediana de tiempo operatorio 7 minutos (R: 4 a 15 minutos). Se presentó una complicación intraoperatoria, correspondiendo al paso de la cinta a través de la uretra. Durante el postoperatorio inmediato se presentaron 7 complicaciones (5%); cinco de ellas fueron sobrecorrección expresada por retención urinaria. En todas se reajustó la cinta por medio de procedimiento ambulatorio a las 48 horas. No hubo hematomas ni infección de la zona operatoria. El alta se dio a las 12 horas en los casos de TVT-O sin asociación a otra cirugía. En el postoperatorio tardío se registró una exposición de la cinta en la pared vaginal anterior. Seguimiento promedio para la serie fue de 10 meses, con un máximo de 16 meses. Se obtuvo la cura de la IOE en 128 pacientes (95%), mejoría en 5 (4%) y falla en 2 (1%). Conclusión: TVT-O es una técnica quirúrgica para el tratamiento de la IOE, con resultados muy promisorios. Sin embargo, de la misma forma que los otros tipos de TOT, requiere una evaluación a largo plazo respecto a su eficacia Objective: To review the results obtained in our experience in the application of TVT-O for surgical correction of stress urinary incontinence (SUI). Patient and Method: Prospective pursuit of 135 patients submissive TVT-O in Las Condes Clinic. Results: The median age was 55 years (R: 38 to 74 years), BMI 27.5 (R: 23 to 34) and vaginal parity 2 (R: 0 to 5). Media operating time was 7 minutes (R: 4 to 17 minutes). One intraoperative complication appeared corresponding to the passage of the tape through urethra. Seven patients developed complications in immediate operative time. Five cases presented urinary retention. In them the tape was readjusted to 48 hours by ambulatory procedure. Hematomas and infections of the wounds were not registered. The discharge at home occurred in the cases of TVT-O without other surgery association at 12 hours. In remote operative period a case of tape exposition in the anterior vaginal wall was registered. The average of pursuit for the series was 10 months, with a maximum of 16 months. The cure of the SUI was obtained in 128 (95%) patients, improvement in 5 (4%) and fails in 2 (1%). Conclusions: TVT-O is a surgical technique for the treatment of the SUI with very promissory results to the present date. Nevertheless, of the same form that the other types of TOT requires a long time to evaluate the real effectiveness
- Published
- 2006
46. Fratura de pênis com trauma uretra
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Arlindo Monteiro de Carvalho Junior, Fábio Martinez de Melo, Gabriella Alves de Lima Félix, Juliana Fernandes Sarmento, and Maria Luisa Dutra Capriglione
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Wounds and injuries ,Genitalia, male ,Penis ,Urethra ,Emergency treatment ,Surgery ,RD1-811 - Abstract
We reported a case of a twenty-nine-year-old male who presented a penile fracture associated with urethral injury caused by a sexual intercourse. An ideal anamnesis and a special physical examination were determinant to correct diagnostics. Ultrasonography and uretrocistography must be performed for confirmation. The treatment is based on the presence of associated urethral injury. The surgical repair of cavernous body and urethra can produce good results, with a favorable prognosis and minimal rate of complications.
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47. Duplicação uretral em homem adulto
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Marcelo Leite Ottoni, Maria Cristina Dornas, Irineu Rubstein, Carlos Alberto Basílio de Oliveira, and Antonio Carlos Iglesias
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Epispadias ,Urethra ,Surgery ,RD1-811 - Abstract
Urethral duplication is a rare congenital anomaly. The clinical presentation and treatment varies because of the different anatomical patterns of this abnormality. We report a case of this entity in the adult male patient. The clinical, radiological and endoscopic findings, as well as the treatment are discussed.
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48. Emprego da submucosa intestinal suína em uretroplastias complexas
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Paulo César Rodrigues Palma, Cássio Luís Zanettini Riccetto, and Marcelo Thiel
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Urethroplasty ,Urethral stricture ,Fistula ,Intestinal mucosa ,Urethra ,Surgery ,RD1-811 - Abstract
We report the use of Porcine Intestinal Submucosa (PIS) in association with Johanson technique for urethroplasty, in the treatment of recurring urethral stenosis. The patient had obliterans xerotica balanitis and had previously undergone 15 internal uretotomies as well as various unsuccessful urethral dilations. As a result of stenotic extension, another surgery was planned using Johanson technique. During the first part of the surgery, intense local fibrosis was observed, which required greater care and protection to avoid fistulae formation. PIS was interposed to reduce the chances of the occurrence of this dreaded complication. During the second part of the surgery, a skin flap obtained from tissue parallel to the urethral plateau was used to prepare a neourethra according to the norms of this technique. PIS was fixed at its extremities, and interposed between the neourethral suture and the skin suture to prevent any contact between them. The procedure was completed with the use of meatoplasty and glandulaplasty. After 6-month follow up, clinical and urodynamic improvement could be seen. If these results can be confirmed by more extensive studies, PIS will provide new perspectives for complex urethroplasties.
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49. Urethral reconstruction in patients previously treated with Memokath™ urethral endoprosthesis.
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Angulo JC, Pankaj J, Arance I, and Kulkarni S
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- Aged, Device Removal, Disease Progression, Epididymitis etiology, Equipment Design, Humans, Male, Middle Aged, Mouth Mucosa transplantation, Postoperative Complications etiology, Recurrence, Transplantation, Heterotopic, Urinary Tract Infections etiology, Urodynamics, Urologic Surgical Procedures, Male instrumentation, Plastic Surgery Procedures methods, Stents adverse effects, Urethra surgery, Urethral Stricture surgery, Urologic Surgical Procedures, Male methods
- Abstract
Purpose: To evaluate the role and success rate of urethral reconstruction in patients with urethral stricture previously treated with thermos-expandable Memokath™ urethral endoprosthesis., Materials and Method: A case series of patients with urethral stricture and Memokath™ endoprosthesis treated with urethroplasty is presented. Reconstruction was decided due to stricture progression or complications derived from primary stent treatment. Age, stricture and stent length, time between stent placement and urethroplasty, mode of stent retrieval, type of urethroplasty, complications and voiding parameters before and after urethroplasty were evaluated. Successful outcome was defined as standard voiding, without need of any postoperative procedure., Results: Eight cases with bulbar urethra stricture were included. Memokath™ was endoscopically retrieved before urethroplasty in 6 (75%) and by open urethrotomy at the time of urethroplasty in 2 (25%). Technique of urethroplasty was dorso-lateral onlay buccal mucosa graft in 5 (62.5%) cases and excision and primary anastomosis, anastomotic urethroplasty, and dorsal onlay buccal mucosa graft in one (12.5%) case each. There was no failure at 26±21.5 months median follow-up. Total IPSS, QoL, Qmax and postvoid residual significantly improved (P<.05). The only complication presented was epididymitis and penile shortening in one patient (12.5%)., Conclusions: Urethroplasty after re-stricture or other complications in patients with temporary Memokath™ urethral stent is a viable and definite option of reconstruction with excellent results in the short term and few complications. One-side dorsolateral onlay buccal mucosa graft augmentation is the optimal technique for this indication., (Copyright © 2018 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2019
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50. Evolución del conocimiento en patología uretral en Valencia desde finales del siglo XIX hasta mediadidos del siglo XX: Análisis documental histórico
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Cánovas Ivorra, José Antonio, Tramoyeres Galvan, Alfredo, Navalón Verdejo, Pedro, Pérez Albacete, Mariano, López Alcina, Emilio, and Zaragozá Orts, Julio
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Urethra ,History of urology ,20th century ,Siglo XX ,Uretra ,Historia de la Urología - Abstract
OBJETIVO: La patología de la uretra ha suido siempre un interesante tema de estudio, apareciendo ya en los textos de 600 años a.C., donde se describen los dilatadores de madera y metal. En la época judeo-musulmana aparecen las primeras uretrotomías externas, y Francisco Díaz describe en 1588 el tratamiento de las carnosidades de la verga. Con Civiale y Maisoneuve, entre 1700 y 1800, aparece la descripción del uretrotomo, y finalmente a mediados del siglo XIX, se comienza con la búsqueda de tejidos capaces de sustituir a la uretra. MÉTODOS: Revisamos todos los artículos de los autores valencianos de la época referidos a la patología uretral, publicados fundamentalmente la Revista Valenciana de Ciencias Médicas. RESULTADOS: Destacamos el uso de las bujías y sondas en el abordaje de la patología estenótica uretral, por varios autores, con sus ventajas e inconvenientes. Asimismo, la descripción de una uretrotomía externa por el Prof. Mollá. Finalmente destacamos el tratamiento de una rotura de uretra posterior mediante tunelización por el Dr. Alfredo Tramoyeres. CONCLUSIONES: A pesar de no ser una patología con un alto volumen de publicaciones, ha interesado desde siempre a los autores. Exponemos todos los tratamientos, técnicas de sondaje y la dilatación como primera opción. OBJECTIVES: Urethral pathology has always been an interesting topic for study, being present in texts from 600 years B.C, where wood and metallic dilators are described. First external urethrotomies appear in the Jewish-Muslim period, and Francisco Diaz describes in 1588 the treatment of the prostate in his book "Tratamiento de las carnosidades de la verga". With Civiale and Maisoneuve, between 1700 and 1800, appears the description of the urethrotome, and finally in the middle XIX century starts the search for adequate tissues to replace urethra. METHODS: We review all articles on the topic of urethral pathology from authors from Valencia in that period, mainly published in the journal "Revista Valenciana de Ciencias Médicas". RESULTS: We emphasize the use of bulbs and sounds in the approach to urethral stenosis by several authors, with their advantages and limitations. We also emphasize the description of external urethrotomy by Prof. Molla. Finally, we point out the treatment of a posterior urethra fracture by tunneling reported by Dr. Alfredo Tramoyeres. CONCLUSIONS: Despite not being a topic with a high volume of publications, it has always interested authors. We describe all treatments, and sound insertion and dilation techniques as first option.
- Published
- 2005
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