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Mesoamerica emerged in regional relations thanks to different cooperation strategies between Mexico, Central America, Colombia and the Dominican Republic that have resulted in what is known today as the Mesoamerica Integration and Development Project. However, ten years after its creation, most of the studies in this regard are descriptive and use an institutional approach that does not distinguish other relevant aspects such as the inclusion of nongovernmental actors and their participation in this regional program. In order to make a first approach to these aspects within the Mesoamerica Project, this paper proposes the use of the International Political Economy theoretical approach of British origin, in the interest of identifying those analytical elements that will go beyond the traditional approach and deepen our knowledge of this program. [ABSTRACT FROM AUTHOR]