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Background: Endometriosis is the presence of functional endometrial tissue in the pelvic peritoneum and it affects several age groups. That is why the impact of endometriosis in quality of life is considerable. The objective of this study was to evaluate the effectiveness of dienogest in patients with pelvic pain associated to endometriosis (PPAE). Methods: The evaluation of the effectiveness was carried out through a systematic review using the Cochrane methodology. It was used Markov model, which considers two states of health (with and without PPAE), with the possibility of weekly transition. Women between 18 and 45 years with PPAE were included, in a temporary horizon of 26 weeks. A level of statistical significance of 95% was used forap< 0.05, with a multivariate probabilistic analysis of sensibility, as well as a univariate analysis of sensibility in several scenarios. Results: The probability that the female patient did not experience PPAE with the initial treatment was 87.91% with dienogest, 80.07% with danazol, 84.93% with medroxyprogesterone (injectable and oral) and 89.17% with gosereline. The probability that the female patient abandoned her initial treatment was 9% with dienogest, 12.07% with danazol, 9.6 and 6.75% with medroxyprogesterone injectable and oral, respectively, and 10.8 and 3.6% 3-monthly and monthly with gosereline. Conclusion: Compared to danazol, medroxiprogesterone and gosereline, dienogest is the most efficient alternative to treat PPAE. [ABSTRACT FROM AUTHOR]

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Objective: to analyze the prescription of antiviral and antibiotic agents in children with upper airway infection (UAI) during Influenza H1 N1 epidemic. Methods: a cross-section study (01 /04/2009 to 31 / 03/2010) was performed. We analyzed the antiviral and antibiotic agents' prescription and its relation with the presence of the triad of symptom of suspicion (migraine, fever and cough) and the cost for attention (medicines and screening test). Results: 838 children were attendance for UAI, 40.3% with the suspicion triad. In 733 patients, the screening test were done with 155 positive results (120 had the triad). All patient with a positive result received oseltamivir. During the first five months of the epidemic, the medical prescriptions were: antibiotics 60-85%, 0-7% anti-viral and 20-30% symptomatic drug's. At the 6th at 8th months (peak of outbreak) antibiotics 35-70%, anti-virals 20-25% and 10-30% symptomatic drug's. At final months (9th to 11th) antimicrobials 65-80%, antivirals 20-30% and symptomatic 0-10%. The cost for URI attention increased a 27%. Conclusions: medical prescription changed during the epidemic, with an increased in the antivirals, especially for patients with high suspicion for influenza and positive screening test. [ABSTRACT FROM AUTHOR]