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Introduction: Cystic lymphatic malformations, also called cystic lymphangiomas, are very rarely found in the liver. Clinical cases. Two pediatric female preschool-age patients. presented with hepatomegaly due to multi-septated cystic lesions of the liver, who received treatment at Hospital Pediátrico Universitario William Soler, La Habana, Cuba. Results: We report two pediatric cases with giant cystic lymphatic malformation of the liver. In both cases, the diagnosis were based on imaging, laparoscopy and pathology. In one case the treatment was right hepatectomy, whereas in the other, sclerotherapy was performed, both with a favorable outcome. Conclusion: Despite its rarity, this diagnosis should be considered in pediatric patients with hepatic cystic lesions. The recommended treatment is surgical resection, but its indication and extent should be assessed individually for each patient. [ABSTRACT FROM AUTHOR]

BACKGROUND: Lymphatic malformations are developmental anomalies consisting of abnormally formed lymphatic vessels; 50% of these lesions are diagnosed at birth, more than 60% affect head and neck region, most frequently in oral cavity (75%) and the oral tongue is the predominant subsite. The primary treatment for lymphatic malformations is surgical excision. Some literature recommends sclerotherapy as first-line treatment for lymphatic malformations, because of acceptable results and less comorbidities when compared to surgical excision which carries higher complication rate associated with extension, age of the patient and relation with vital structures. CLINICAL CASE: A 37-year-old female patient, who referred increased volume in one third anterior of oral tongue since birth. With pathological anatomy study at two months of life it was diagnosed lymphangioma. At age of 34 years, patient refused surgical treatment, thus, sclerotherapy with bleomycin was proposed, with which obtained a good response. CONCLUSIONS: Intralesional bleomycin is a safe and effective treatment of lymphatic malformations showing acceptable results. [ABSTRACT FROM AUTHOR]

Vascular anomalies are common in children and can be divided into two categories, vascular tumours and vascular malformations: high-flow or low-flow. The latter can be treated in different ways such as lasertherapy, drainage, aspiration, surgery or sclerotherapy depending on the type and location of the lesion. Among the accepted sclerosing agents, bleomycin has proven good results in the treatment of this condition. Herein we present our experience in the treatment of low-flow vascular malformations with intralesional bleomycin injection. This is a retrospective, descriptive study with 30 patients presenting a low-flow vascular malformation treated with intralesional bleomycin injection. Our results are good or excellent in 22 patients and poor in the other 8. According to our case series and the consulted literature, sclerotherapy with intralesional bleomycin injection is an effective and safe treatment for low-flow vascular malformations. [ABSTRACT FROM AUTHOR]

Primary sclerosing cholangitis (PSC) is a chronic cholestatic pathology that affects the intra-and extrahepatic bile ducts, usually in men between 20 and 40 years in 70% of cases. Here we present a case of a female patient 65 years of age with histopathological diagnosis of PSC, the patient has idiopathic pulmonary fibrosis (IPF) treated with Pneumology. Recent studies support the use of transient elastography (FibroScan TE) and monitoring of progressive liver fibrosis and damage especially in patients with comorbidities that have an impaired quality of life. [ABSTRACT FROM AUTHOR]

Background: the pericardiocenthesis is indicated as treatment of cardiac tamponade. The prevention of recurrences can be achieve by pericardial instillation of sclerosing agents, radio-nuclide agents as well as external beam radiotherapy that had given good results in radiosensitivity tumors. Pericardial window, pleuropericardiotomy, pericardiec-tomie and percutaneous pericardiotomie, are used when the pericardiocenthesis cannot be carried out. Clinical case: a female patient, 34 years with cardiac tamponade was attended in the emergency room due to hemopericardium and pericardial metastases of unknown primary tumor. She was managed with pericardial window and systemic chemotherapy. After two year, she is alive without evidence of pericardial effusion recurrence and without evidence of tumor activity. Conclusions: pericardiocentesis is an indication in cardiac tamponade. The multimodal treatment provides better results in patients with metastases to the pericardium and cardiac tamponade. It includes local and systemic chemotherapy and radiation therapy. [ABSTRACT FROM AUTHOR]

Introduction. The effectiveness of intralesional sclerotherapy of lymphangioma with OK-432 (Picibanil) has been proved in several clinical studies. The aim of our study was to review the effectiveness of sclerotherapy of benign tongue cysts with Picibanil as an alternative method to surgical excision. A prospective observational study was carried out to assess the effects of Picibanil on tongue cysts. Material and Method. Between 1995 and 2007 we studied 300 patients with lymphangioma. Twelve of them had tongue cysts which were treated with intralesional application of Picibanil with a dose ranging from 0.01 mg/mL to 0.03 mg/mL. Results. The 12 patients showed good results. In both clinically and by ultrasonograph. However complete regression of the cysts occurred in five cases, while in seven cases the cysts showed atrophy for which reason the remaining cyst was surgically removed. No significant complications after sclerotherapy with Picibanil was observed. Conclusion. OK-432 (Picibanil) is a safe and effective primary method for sclerotherapy of tongue cysts; its use precludes surgical removal in special cases. [ABSTRACT FROM AUTHOR]