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A clinical case of a 20 year-old man from a rural area of Llorente-Nariño, who consulted a local health center after 36 hours of accidental ingesting Gramoxone (paraquat dichloride, 20-30 mL), while under the influence of alcohol, that provoked digestive symptoms, hyperbilirubinemia, elevation of creatinine and hemogram with leukocytosis and neutrophilia, is referred to the third level of health attention in the city of Pasto. During the hospital course he presents epistaxis, kidney failure with need of hemodialysis, oral burns, hyperthermia and two episodes of convulsive seizures clonic-tonic generalized with arterial blood gases, electrolytes, glycemia and other para-clinics within normal ranges during the seizures. It's important to try to give elements to build a clinical criteria to explain neurologic compromise, because is exceptionally strange and complex this type of clinical presentation in cases of intoxication with paraquat. [ABSTRACT FROM AUTHOR]