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Objective: To characterize informed and traditional knowledge on breast cancer, as well as attitudes, and practices for its early detection among 30 to 69 years old women in the urban area of the municipality of Amalfi, Antioquia. Methodology: Crosssectional study using a survey involving 335 women, selected via simple random sampling using housing addresses provided by the Secretariat for City Planning. Results: The combined score for breast cancer knowledge, risk factors, and symptoms was 14 (standard deviation: 3.6) out of 22 possible points, which shows an intermediate understanding of the topic. In 30 to 49 years old women, 82% of them knew what breast cancer self-examination was, 14% knew what clinical breast cancer exams were, and 68% knew what a mammography was. On the contrary, in 50 to 69 years old women, percentages for the same criteria were 62%, 10%, and 63%, respectively. 95% of the respondents reported that early detection methods are important for cancer prevention or its timely treatment. 71.9% of the 39 to 49 years old respondents, as well as 67.1% of 50 to 69 years old women had already performed breast self-examination. 41.5% of women had taken a clinical breast exam, without significant differences between age groups. Only 39.2% of 50 to 69 years old women, had had a mammography. Conclusions: Knowledge on breast cancer, as well as attitudes, and practices for its early detection show deficiencies among the compared age groups; however, women present a favorable disposition towards breast cancer early detection, which may favor a strengthening of knowledge about this type of cancer and engage women in involving themselves in procedures for its detection. [ABSTRACT FROM AUTHOR]

Objective: To describe the core experiences of Boyaca women, undergoing mastectomy for breast cancer, during 2017. Methodology: Qualitative ethnographic type according to the small-scale ethno- nursing, of Leininger's transcultural theory. The participants included ten women key informants and eight general informants. The analysis of the information obtained in the interviews was developed in four phases: 1. Collection, description and documentation of raw data; 2. Identification and categorization of the descriptors and components; 3. Contextual and pattern analysis; 4. Central themes, research findings, theoretical formulations, and recommendations. The analysis was made taking into account the guide proposed by Leininger. The factors of the social and cultural structure, of the model of the rising Sun The experiences of care experienced by women were described identifying a total of two hundred and eight codes and twenty recurring patterns, which were analyzed and according to the level of coding were labeled and coded giving rise to six themes: 1. The accompaniment an important part in the care of the woman subjected to Mastectomy; 2. The strength of faith; 3. Unpleasant effects of treatment; 4. Experience lived; 5. Importance of care in recovery; 6. Feeding basic support in recovery. [ABSTRACT FROM AUTHOR]

A decision tree based system with heuristic weight factors oriented to diagnosis by thermography was developed. The proposed clinical decision support system (CDSS) includes binary decision trees for statistical classification of some diseases of the mammary gland. These include weight constant factors found by the correlation of the variables involved in the development of breast disorders according to the statistical attachment of the thermal features, as well as complementary clinical information (medical history, physical parameters, genetic load and habits, among others), regarding its diagnostic incidence. The certainty of the system for inflammatory disorders is 96%, for fibrocystic mastopathy is 78 %, for fat necrosis is 62% and for breast cancer is 86%. The 14% error is associated to microcalcifications that with the reported thermographic technique it is not possible to differentiate. Thus, it is possible to catalog the risk of a patient having a condition according to the results obtained after conducting a thermal test. Then, with the CDSS the possibility of applying early detection tests in the population suffering from contraindications to perform the others is improved, in addition it allows a comprehensive diagnosis for other patients. [ABSTRACT FROM AUTHOR]

Breast cancer is one of the most common causes of death in the female population worldwide and one of the most prevalent cancers among other types of cancer. An early and adequate diagnosis is a key factor for an appropriate treatment, increasing the probability of survival. In order to enhance the efficiency and effectiveness of a diagnosis, an image analysis system was implemented; its purpose was to provide support for radiologists in detection of lesions from mammograms. Image segmentation techniques were carried out to find breast lesions within the mammograms in the region of interest (ROI), which is related to the area where breast density is concentrated. Breast density is defined as the brightest part on the mammographic image and it is composed by glandular and adipose tissue where breast lesions are likely to be exposed. This study provides a methodology divided in two main segmentation techniques: 1) a region growing technique and 2) split and merge technique. This study also gives a complete description of image analysis and the tools used in it. [ABSTRACT FROM AUTHOR]

Objective: To describe sequence variants in the BRCA1 and BRCA2 genes in a sample of Colombian patients with a personal or family history of breast cancer suggestive of genetic risk. Materials and methods: Case series consisting of 67 patients referred for genetic testing because of suspected hereditary breast and ovarian cancer syndrome (HBOC). Of the 67 cases, 42 (62.7%) met the medical indication criteria of the 2013 National Comprehensive Cancer Network (NCCN) and they were subjected to the entire sequencing of the BRCA1 and BRCA2 genes. A determination was made of the frequency of sequence mutation, variants, and of the clinical significance of the variants found based on the Breast Cancer Information Core (BIC). Results: Mutations were identified for the BRCA 1 gene in six patients (14.3%), no mutation was documented for the BRCA 2 gene, and 43 genetic variants were found in 27 patients (64.2% of 42 cases). Of these, 21 (48.8%) were identified in the BRCA1 gene and 22 (51.2%) in the BRCA 2 gene. Among these variants, 5 pathogenic mutations were found only in the BRCA1 gene and, of those, only 1 had been reported previously in Colombia. Conclusions: This study identifies pathogenic genetic variants in the BRCA1 gene not described previously in the Colombian population, as well as others known in different populations. Therefore, it helps expand knowledge regarding the variants of the BRCA1 and BRCA2 genes in the Colombian population. However, additional studies are required with sufficient power and methodological quality to estimate the frequency of sequence mutations and variants for the BRCA1 and BRCA2 genes in Colombian women suspected of having the hereditary breast or ovarian cancer syndrome. [ABSTRACT FROM AUTHOR]

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Copyright of Investigaciones ANDINA is the property of Fundacion Universitaria del Area Andina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)