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Lupus erythematosus tumidus is an uncommon disorder characterized by erythematous urticarial non-scarring plaques. It has high photosensitivity and a clinical course with relapses and spontaneous remission. Histologic features include perivascular and periadnexal lymphocytic infiltration and interstitial mucin deposition, with the absence of changes on the epidermal surface. We present the case of a 55-year-old male who presented with an erythematous urticarial plaque on the forehead. Initially, we consider Hansen's disease due to its prevalence and regional epidemiology. [ABSTRACT FROM AUTHOR]

INTRODUCTION: Lupus erythematosus (LE) is a rare autoimmune disease in males that presents multiple clinical manifestations related to its prognosis. The etiology is unknown, nevertheless it is related to ultraviolet radiation exposure and modification in lymphocytic function. Lupus erythematosus profundus (LEP) is the clinical manifestation found in only 1% to 3% of patients with cutaneous lupus erythematosus (LEC) and only 10% of the cases reported in the literature are males. It is recalcitrant to treatment with frequent exacerbations. Up to 50% of patients with LEP progress to systemic lupus erythematosus (SLE) during the course of the disease. CASE: We present the case of a previously healthy 16-year-old man who presented with an indurated plaque on the left cheek with a chronic course. The incisional biopsy revealed LEP. Work up analysis found no systemic lupus erythematosus involvement. The patient received topical corticoid treatment and strict photoprotection with improvement of the erythema and reduction of the indurated area. CONCLUSION: LEP is a rare dermatosis in males, so the current literature may not be representative in this sex. It is necessary to carry out a comprehensive approach at diagnosis with serum and rheumatological laboratory tests. It is of outmost important to be able to identify early signs and symptoms that suggest progression to SLE or lymphoma. [ABSTRACT FROM AUTHOR]

Linear discoid lupus erythematosus is a chronic disease of unknown etiology. It is characterized by erythematosus plaques that follow Blaschko's lines and is an unusual variant of discoid lupus erythematosus. The present review describes the case of a female patient who consulted for a lesion on the face and an alopecic area on the scalp associated with manifestations of systemic lupus erythematosus; an adequate response to pharmacological treatment was presented. The search for scientific articles for the development of this report was conducted in the following databases: ClinicalKey, Ovid, and PubMed. It is currently the first clinical case report described of linear discoid lupus erythematosus associated with systemic lupus erythematosus. A literature review will be conducted. [ABSTRACT FROM AUTHOR]

A middle-aged woman presented with immunological, mucocutaneous, hematological and renal signs and symptoms, with a final diagnosis of systemic lupus erythematosus with toxic epidermal necrolysis (TEN) type manifestation. Systemic lupus erythematosus is accompanied by multiple dermatological manifestations, of these, different forms of bullous lesions have been described, including lupus erythematosus with TEN-type manifestation, an entity with lower morbidity and mortality than classic TEN and which normally presents an excellent response to systemic corticosteroids. The presentation of this clinical case is considered relevant due to its rarity and because it can be an important clue for the diagnosis of systemic lupus erythematosus. [ABSTRACT FROM AUTHOR]

Systemic Lupus Erythematosus (SLE) is a chronic multisystem autoimmune disease that affects multiple organs through autoantibodies and immune complexes, causing symptoms according to their location and can range from mild to very severe and sudden. It is cutaneous manifestation may be presented with systemic manifestation and can become very intense, so that prevails extensive skin necrosis. Because there is not an exclusive symptom or finding for diagnosis of the disease, we rely on clinical and laboratory findings, and the American College of Rheumatology has established criteria that are used to confirm the diagnosis in patients admitted to major studios. The treatment depends on the clinical manifestations, the presence/absence of involvement of vital organs and your approach must be multidisciplinary. Their survival has improved in the last decade thanks to early diagnosis and treatment. However, its prognosis remains serious. The present case report is a 32-year-old woman diagnosed with severe SLE with subacute cutaneous presentation, and good response to treatment after diagnosis. Therefore it is necessary that the primary care physician knows how to recognize this type of patient in order to make an early diagnosis so that an effective and timely management of these patients can be established. [ABSTRACT FROM AUTHOR]

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Bullous systemic lupus erythematosus is a rare disease, more commonly present in young women. It is characterized by prevailing tense subepidermal blisters, but not exclusively in areas exposed to light. It may be accompanied by mucosal involvement. The case of a 15-year-old girl with no relevant past medical history and a two months generalized tense evolution bullous lesions is presented. Bullous systemic lupus erythematosus diagnosis was confirmed, and treatment was started with dapsone. She presented a slow creeping improvement with a drug that traditionally produces a marked improvement. [ABSTRACT FROM AUTHOR]