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Copyright of Tecnología y Ciencias del Agua is the property of Instituto Mexicano de Tecnologia del Agua (IMTA) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: cancer treatment is one of the great challenges facing today’s scientific society. In this health fight, drug-conjugated antibodies (ADCs) are being developed, drugs capable of causing cell death by transporting and releasing cytotoxic compounds into tumor cells. They are composed of a monoclonal antibody (of protein nature) linked to a cytotoxic drug (of lipophilic character) through a linker. Formulations must be designed to maintain this binding during storage and administration. Objective: identify the medicines marketed in Spain whose active ingredient is an antibody-drug conjugate, studying techno pharmaceutical aspects, especially the components of their formulations Method: since this type of drugs belongs to the ATC group L01F, they have been identified through the search engine of the Spanish Agency of Medicines and Health Products. The search for their technical sheets, along with articles of review and research related to the topic, as well as the Handbook of Pharmaceuticals Excipients, has enabled the execution of the techno pharmaceutical study. the formulation of the tested conjugates to drugs marketed in Spain belonging to the ATC L01F group corresponding to “monoclonal antibodies and tested conjugated to drugs” identified through the search engine of the Spanish Agency of Medicines and Health Products has been studied. Results: different aspects of this group of drugs have been analyzed, such as the pharmaceutical form, the route of administration, conservation and especially the techno pharmaceutical formulation. The nature of the active ingredient and the requirements of the formulations based on their characteristics have been studied in depth. Conclusions: the eight antibody-drug conjugates approved in Spain are presented in the form of lyophilized powder in a vial and should be stored between 2-8 ºC. For administration, they are reconstituted, initially obtaining a concentrate, which is then diluted and administered as an intravenous infusion or drip. Their typical formulation includes a lyoprotector, an antiaggregant, a pH regulator, and eventually antioxidants or viscosity reducers. [ABSTRACT FROM AUTHOR]

Copyright of Bosque (03048799) is the property of Facultad de Ciencias Forestales, Universidad Austral de Chile and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The objective of this research was to establish the relationship between selfconcept, academic performance and gender among undergraduate students at a public university in the city of Pasto, Colombia. It was approached from an integrative perspective, with dominant status and sequential order: quantitative→ qualitative. A total of 684 students from first to tenth semester of 11 faculties participated. The AF5 Self-Concept test, semi-structured interviews and focus group discussions were used. The most significant findings show a correlation between academic self-concept and performance. Likewise, a correlation was found between emotional self-concept and performance in women. In the qualitative phase, categories such as stereotypes, prejudices, and discrimination associated mainly with women and sexual diversities emerged, along with protective factors and coping styles in mental health. It is concluded that prejudice, stereotypes, and discrimination shape self-concept, but protective factors and coping styles allow overcoming these challenges and achieving academic success. [ABSTRACT FROM AUTHOR]

The article summarizes the history of the Palatine Chapel of the Dukes of Medina Sidonia and the Main Church of Sanlúcar de Barrameda. Both buildings have been declared Historical-Artistic Monuments, and although some studies have been carried out on the Main Church, there is still much to be investigated. The importance of deeply understanding cultural assets for their effective protection is highlighted. Additionally, the creation of the Diocesan Historical Archive of Jerez in 1983 is mentioned, which has improved the conditions for the conservation and accessibility of sacramental books. The Main Church was restored in the 1990s and is in need of maintenance, while the Ducal Palace has flourished as a civic and cultural center under the direction of Lilianne Maria Dahlmann. The Ducal Archive has been an important source for historical research on the House of Medina Sidonia. The presence of the Ducal Tribune in the Main Church has been a unique and relevant aspect in its history. The article is a doctoral thesis that focuses on the history and relationship between these two religious foundations in Sanlúcar de Barrameda, Spain, with the aim of recovering their memory and serving as a model for future comparative studies. [Extracted from the article]

The article is a review of the book "The International Legal Status of Victims of International Crimes. Rights of Victims, Transitional Justice, and the International Criminal Court" written by Félix Vacas Fernández. The book analyzes the paradigm shift in the recognition of the rights of victims of international crimes and its impact on the protection of human rights, international criminal law, and transitional justice. The author examines the role of victims in the criminal justice system and the emergence of a victim-centered approach instead of focusing on the perpetrators. It also explores the relationship between justice and peace in the context of transitional justice. The book is divided into two parts and addresses both the theoretical foundation and the practical implications of this paradigm shift. Professor Vacas warns that despite progress, the victim-centered approach has not yet crystallized and must be accepted and internalized in the development of the system. This implies recognizing and conceptualizing victims of international crimes and establishing a comprehensive and effective international legal status for them. These changes limit the discretion of power through law and guarantee victims' rights to truth, justice, reparation, and non-repetition. The definition of victims of international crimes poses important problems and debates, such as the distinction between direct and indirect victims. At the international level, treaties and conventions recognizing victims have been adopted, but the definition was not established until 1985. The international legal status of victims has developed in a fragmented but coherent manner and has quickly spread to domestic law in states. The Declaration of Basic Principles of Justice for Victims of Crime and Abuse of Power and the Basic Principles and Guidelines on the Right to Victims are noteworthy. The text analyzes the protection of human rights and the legal status of victims in the European and international spheres. The efforts of the Council of Europe and the European Union to protect victims of violent crimes and terrorist acts are mentioned. The legal status of victims recognized by the International Criminal Court is also examined. The author highlights the rights of victims to access justice, participation, protection, reparation, and information. Overall, reading this comprehensive and stimulating work on human rights and transitional justice is recommended. [Extracted from the article]

Copyright of Journal of Sport & Health Research is the property of Journal of Sport & Health Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Anuario de Psicología Jurídica is the property of Colegio Oficial de Psicologos de Madrid and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of MEDISAN is the property of Centro Provincial de Informacion en Ciencias Medicas de Santiago de Cuba and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Which came first, the chicken or the egg? That is not a pun, joking or irrelevant question. Two hypotheses have tried to answer it. The first, and accepted for years, proposes that the evolutionary process went from oviparity, through an Embryonic Retention (ER) phase, to viviparity. In other words, the simpler egg came first, which hatched into the more complex chicken. That is known as the terrestrial model. Indeed, fishes typically lay eggs, albeit some sharks are viviparous. Even some living (extant) mammals are oviparous, (monotremes like platypus and echidnas). But new evidence has challenged such traditional view, proposing that it was the other way round. Thus, first came the chicken, which eventually laid the egg. That is the Extended Embryo-Retention (EER) model. In the first evolutionary step of this scenario, ancient reptiles, birds and mammals gave birth to offspring. Subsequently, some of them developed oviparity. Indeed, several archaeological and phylogenetic discoveries have shown that first, during the ER period, thin layers of tissues (extraembryonic membranes) evolved for a better development of the embryo, given rise to the amniotes. It is known that living reptiles (like crocodiles and turtles) and birds typically show non-EER oviparity. But curiously, most lizards, snakes and mammals exhibit oviparity with EER or viviparity. While the debate continues, both archaeology and molecular biology will contribute to clarify this interesting topic. [ABSTRACT FROM AUTHOR]

Copyright of Archaeobios is the property of Arqueobios and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Iberoamericana de Ingeniería Mecánica is the property of Editorial UNED and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Economic & Social Science Research (JESSR) is the property of Editorial Grupo AEA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Médicas UIS is the property of Universidad Industrial de Santander and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Fides et Ratio is the property of Universidad La Salle de Bolivia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista CEA is the property of Revista CEA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Clínica Contemporánea: Revista de Diagnóstico Psicológico, Psicoterapia y Salud is the property of Colegio Oficial de Psicologos de Madrid and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Iberoamericana de Ciencias de la Actividad Física y el Deporte is the property of Revista Iberoamericana de Ciencias de la Actividad Física y el Deporte and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The Academic Satisfaction Scale (ESA) has presented adequate levels of reliability and validity in university students internationally. However, no psychometric studies have yet been presented on Spanish university students. Therefore, the objective of this research was to evaluate the psychometric properties of the academic satisfaction scale in a sample of Spanish university students. A cross-sectional study was carried out, in which 2835 university students participated (71.1% women and 28.9% men), with an average age of 21.8 years (SD=2.97), belonging to the levels of Bachelor's, Master's, Own Degrees and Doctorate of the Complutense University of Madrid (UCM). The factorial structure of the scale was evaluated from exploratory and confirmatory factorial analyses, and the results ratified the unidimensional theoretical structure. The academic satisfaction factor presented adequate levels of reliability and the findings provide evidence for its use in Spanish university students. Likewise, the evidence of validity by external criteria indicates how academic satisfaction is associated in a significant and positive way with the cognitive restructuring dimension of the Coping Strategies Inventory (CSI). The results are discussed based on the theoretical and empirical evidence available. [ABSTRACT FROM AUTHOR]

Copyright of Cuadernos de Prehistoria y Arqueologia is the property of Cuadernos de Prehistoria y Arqueologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Spal: Revista de Prehistoria y Arqueologia de la Universidad de Sevilla is the property of Spal. Revista de Prehistoria y Arqueologia de la Universidad de Sevilla and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of REDER: Revista de Estudios Latinoamericanos sobre Reducción del Riesgo de Desastres is the property of Corporacion Gestion de Riesgos y Desastres (GRID-Chile) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Complutum is the property of Universidad Complutense de Madrid and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Entramado is the property of Universidad Libre Seccional Cali and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zephyrus is the property of Ediciones Universidad de Salamanca and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

We present new data on the exploitation of stone for construction purposes in the protohistory of the southeast of the Iberian Peninsula, specifically from the site of Los Cucos (Bogarra, Albacete) and a possible supply quarry. This study aims to connect the unpublished architectural data with the application of Fourier transform infrared analysis (FTIR). [ABSTRACT FROM AUTHOR]

INTRODUCTION: Accidental ingestion of magnetic foreign bodies has become more common due to the greater availability of toys with these elements, being a clinical problem between 6 months and 3 years of age, which must be treated promptly since they could cause life-threatening gastrointestinal complications. CLINICAL CASE: A 4-year-old male schoolboy, who presented abdominal pain of 4 days of evolution, colic type, intermittent, without other symptoms; clinically stable, the abdomen without data of peritoneal irritation. An AP and lateral standing X-ray of the abdomen is performed, which shows images of radiopaque foreign bodies (chain of magnets) in the gastric chamber and partial intestinal pneumatization. An endoscopy was performed where 4 spherical magnets embedded in the gastric mucosa that conditioned transmural perforation were visualized. An exploratory laparotomy was performed, finding a perforation in the posterior face of the gastric body that fistulized towards the jejunum and another mirror perforation in the colon, and a chain of 15 circumferential magnets was extracted from the gastric cavity. CONCLUSION: The ingestion of magnets must be diagnosed in a timely manner through a directed questioning, based on a simple abdominal X-ray, since this will define the diagnosis and early endoscopic and/or surgical treatment and thus avoid greater gastrointestinal complications secondary to the electromagnetic charge of the magnets, time of ingestion, location and number of foreign bodies. [ABSTRACT FROM AUTHOR]

Copyright of DYNA - Ingeniería e Industria is the property of Publicaciones Dyna SL and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A suitable design of manufacturing facilities can increase the efficiency of a company's internal operations by optimizing material handling and flow costs. This paper addresses the facility layout planning problem (FLP), modeled as a quadratic allocation problem (QAP), applied to a company dedicated to the production of liquors. The problem was solved using the Computerized Relative Allocation of Facilities Technique that belongs to the heuristic algorithms, which allowed us to determine the best allocation of the departments, considering the distances traveled and the material flow costs. Subsequently, a simulation was carried out to evaluate the new distribution given the company's daily activities, considering the variability of loading and unloading times. The simulation results suggest that, if the new layout is implemented, material flow costs and times would be reduced by 13.22 % and 4.28 %, respectively. [ABSTRACT FROM AUTHOR]

Objective: to carry out a systematic review on the educational inclusion of adolescents with disabilities at the secondary level in educational institutions in Latin America. Method: 33 scientific articles from the databases: Scopus, EBSCOhost, SciELO, Dialnet, REDIB and Redalyc were analyzed under the criteria of the PRISMA protocol. Results: three dimensions were identified: types of disability, resources that favor the implementation of educational inclusion, and barriers; both of these are described according to the pedagogical and psychological elements. Visual and hearing disabilities are mainly related to pedagogical studies, while intellectual disabilities are related to interaction and self-determination. Conclusion: there is clarity in the regulations and conceptions on educational inclusion and disability; however, the adjustments in the educational system are not completely in tune because infrastructure, political, pedagogical and cultural barriers persist that slow down the achievement of inclusive educational models. [ABSTRACT FROM AUTHOR]

Aim: To evaluate long-term results in the surgical treatment of sacrococcygeal pilonidal disease (SPD) comparing the different surgical techniques used, complications, healing time and recurrence. Material and Method: Retrospective cross-sectional study. The files of the patients operated on for EPS between January 2017 and August 2021 were reviewed. For follow-up, information was obtained from the records of the periodic controls in our center; those who did not continue with these controls were contacted by telephone. Results: 309 cases were collected, with a mean follow-up of 15.6 months. The most used techniques for the chronic phase of EPS were marsupialization and Karydakis, achieving complete wound healing in 54.5 and 18.2 days, respectively. The presence of complications prolonged the healing time by 46.5 days in Karydakis, with minimal impact on marsupialization. The recurrence rate was lower in Karydakis and in the acute stage when unroofing and curettage were performed. Antibiotic prophylaxis did not increase the risk of postoperative complications. Discussion: The development of postoperative complications has a greater impact on the healing of the closed technique than in the open technique, the last one seems to be more tolerant in terms of healing in the presence of complications. Conclusion: The intervention with the Karydakis technique achieves healing of the surgical wound in less time than marsupialization, however, when complications develop, this time increases 3.5 times more. Recurrence was lower in Karydakis. In abscess weaning and curettage is recommended over the exclusive drainage. [ABSTRACT FROM AUTHOR]