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Objectives: The pancreatic ducts and duodenal papillae present variable location and morphology. This variability must be known when performing endoscopic, surgical or radiological procedures that involve them; necessary in the diagnosis and treatment of bilio-digestive pathologies. The objective of the present study is to review the anatomy of these structures, record possible variations and carry a review of the literature. Material and method: A descriptive, observational anatomical study was carried out, in which 40 duodenum-pancreatic blocks were dissected from adult corpses of both sex preserved in formaldehyde. We recorded the frequency, location and morphology of both duodenal papillae, the prevalence of the main and accessory pancreatic ducts and the site of junction between the two ducts. These findings were compared with classic and recent literature. Results: The percentage relative frequency of the major and minor duodenal papillae was 100% and 87.5% respectively. The first was predominantly located at the second portion of the duodenum, in its middle third and in the posteromedial sector (82.5%); while the minor papilla was found in the upper third of the second duodenal portion, anteromedial sector (80%). The main and accessory pancreatic ducts were found in 97.5% and 87.5% of the cases, respectively. The junction of the pancreatic ducts was found in 54.3%. Conclusions: Classical anatomy prevailed in the studied structures. [ABSTRACT FROM AUTHOR]