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Copyright of Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica is the property of Asociacion Colombiana de Dermatologia y Cirugia Dermatologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Resumen Introducción Nuestro objetivo fue evaluar si el número y el volumen de las biopsias pulmonares quirúrgicas (BPQ) influyen en el diagnóstico de la enfermedad pulmonar intersticial difusa (EPID). Métodos Estudio retrospectivo de BPQ por sospecha de EPID en los pacientes de la Clínica Mayo desde enero de 2002 hasta enero de 2010. Los datos se recogieron y analizaron en la institución. Resultados Se analizaron 311 pacientes. El número medio de biopsias fue de 2,05 (DE 0,6); una biopsia en 50 (16%), dos en 198 (63,7%), tres en 59 (19%) y cuatro en 4 (1,3%). El diagnóstico histopatológico fue: definitivo (específico) en 232 (74,6%), descriptivo (no específico) en 76 (24,4%) no hubo diagnóstico en 3 (1%). Tras excluir a los pacientes sin diagnóstico (n = 3), hubo 50 pacientes con solo una biopsia, 196 con dos y 62 con tres o cuatro. El rendimiento de diagnóstico definitivo fue similar en los tres grupos (37/50 [74%], 150/196 [77%] y 45/62 [73%]). El valor p de Chi-cuadrado fue 0,8. El análisis del índice de propensión entre pacientes con una BPQ y pacientes con más de una BPQ tampoco mostró ninguna diferencia en el rendimiento diagnóstico. En cuanto al volumen de las biopsias, el volumen total medio fue 34,4 cm 3 (DE = 46). En los pacientes sin diagnóstico, 41,2 cm 3 (3 casos), en pacientes con diagnóstico específico, 33,6 cm 3 (232 casos [DE = 47]) y en pacientes con un diagnóstico descriptivo: 36,6 cm 3 (76 pacientes [DE = 44]). El volumen de la biopsia no influyó en el rendimiento de la histopatología (ANOVA, p = 0,8). Conclusiones El número o el volumen de las muestras de biopsia quirúrgica no parecen influir en el diagnóstico. Según nuestros resultados creemos que una sola muestra de un área representativa puede ser suficiente para el diagnóstico. Se deben realizar ensayos prospectivos aleatorizados para optimizar la BPQ en las EPID. Introduction Our objective was to evaluate whether the number and volume of surgical lung biopsies (SLB) influence the diagnosis of diffuse interstitial lung disease (ILD). Methods Retrospective study of SLB for suspected ILD in patients from the Mayo Clinic from January 2002 to January 2010. Data were collected in the institution and analyzed. Results 311 patients were studied. Mean number of biopsies was 2.05 (SD 0.6); 1 biopsy in 50 (16%), 2 in 198 (63.7%), 3 in 59 (19%) and 4 in 4 (1.3%). Histopathologic diagnosis was: definitive (specific): 232 (74.6%), descriptive (non-specific): 76 (24.4%), no diagnosis: 3 (1%). After excluding patients without diagnosis (n = 3), there were 50 patients with only 1 biopsy, 196 with 2 and 62 with 3 or 4; the definitive diagnostic yield was similar in all 3 groups (37/50; 74%, 150/196; 77%, and 45/62; 73%) (Chi-square, p value 0.8). The propensity score analysis between patients with 1 SLB and patients with more than 1 SLB also showed no difference in diagnostic yield. Regarding the volume of biopsies, mean total volume was 34.4 cm 3 (SD 46): 41.2 cm 3 (3 cases) in patients with no diagnosis; 33.6 cm 3 (232 cases, SD 47) in patients with specific diagnosis; and 36.6 cm 3 (76 cases, SD 44) in patients with descriptive diagnosis. Biopsy volume had no influence on histopathology yield (ANOVA, p value 0.8). Conclusions The number and volume of the biopsy specimens in SLB did not seem to influence diagnosis. Based on our results, we believe a single sample from a representative area may be sufficient for diagnosis. Randomized prospective trials should be performed to optimize SLB for ILD. [ABSTRACT FROM AUTHOR]

Copyright of Revista Latinoamericana de Estudios Educativos is the property of Centro de Estudios Educativos, A.C. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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An interview with British film archivist David Francis is presented. He suggests the necessary changes film archivists must implement for progress in the field. Francis discusses the impediments for making greater proportions of film archives available to the general public, the conflict that exists between preservation and presentation of films, and cinema's importance to the twentieth century's arts and history.