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BACKGROUND: The postrema area syndrome is included in neuromyelitis optica spectrum disorders, which contain a heterogeneous group of autoimmune and demyelinating inflammatory disorders of the central nervous system, associated frequently with the specific water channel antibody of aquaporin-4 (AQP4). The postrema area syndrome is characterized by intractable nausea, vomiting and hiccups without any apparent cause. The postrema area is a circumventricular organ with abundant AQP4 located on the floor of the fourth ventricle with multiple connections to structures of the brainstem and hypothalamus; with important physiological functions in the control of vomiting reflex, appetite and blood pressure, among others. CLINICAL CASE: A 32-year-old female patient with postrema area syndrome, who started with intractable hiccups associated with the AQP4 antibody. CONCLUSIONS: The postrema area syndrome is a manifestation of the neuromyelitis optica spectrum disorders with a higher incidence in the adult population; it should be suspected in the presence of intractable emesis or hiccups that persist for more than 48 hours without a probable cause. [ABSTRACT FROM AUTHOR]

Copyright of Revista Colombiana de Psicología is the property of Universidad Nacional de Colombia, Departamento de Psicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)