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BACKGROUND: Lichen nitidus is an infrequent dermatosis and especially prevalent in the pediatric population, although it also affects adults. It is typically characterized by papules with a smooth or umbilicated surface located on the extremities, trunk, and genitals. However, it exhibits various clinical manifestations that may vary according to location and subtype, making its diagnosis in these cases a challenge for the dermatologist. CLINICAL CASE: A 60-year-old female patient with a 9-month history of generalized, pruritic and some purpuric lesions, associated with keratoderma-type palmoplantar involvement. A biopsy was taken from one of the lesions located on the left forearm, compatible with generalized lichen nitidus. CONCLUSIONS: It is important to know the clinical varieties of this dermatosis, especially the generalized form. In these cases, the identification of typical lichen nitidus lesions in some body segments, central palmar involvement, and histological findings are key. [ABSTRACT FROM AUTHOR]

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The porokeratosis are a group of disorders of the skin keratinization of acquired or hereditary character. Its clinical expression is a macular or annular plaque, atrophic in the center and with well-defined hyperkeratotic edges and the histological picture is a compact parakeratotic column, called cornoid lamella. The number and distribution of lesions define the different clinical forms of porokeratosis: Mibelli, disseminated superficial actinic porokeratosis (DSAP), linear porokeratosis, palmoplantar porokeratosis and punctate porokeratosis. We report 3 cases and make a brief review of the literature. [ABSTRACT FROM AUTHOR]

Olmsted syndrome, irst described in 1927, is a diffuse palmoplantar keratoderma associated with other abnormalities. This condition starts with perioriicial erythema followed by progressive perioral hyperkeratosis running in parallel with palmo-plantar keratoderma. To date there is no cure, but oral retinoids may improve general care and quality of life of these patients. This paper reports the case of a female child with Olmsted's syndrome and describes the advances in the genetic basis of this disorder in the last three years. [ABSTRACT FROM AUTHOR]