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Copyright of Revista Ciencias de la Salud is the property of Colegio Mayor de Nuestra Senora del Rosario and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Iberoamericana de Micologia is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Invasive candidiasis is an important epidemiological problem especially in critically ill and immunocompromised patients, causing high mortality rates. Also, in the last decades an emergence of non-albicans species has been observed. Objective: To determine the frequency and susceptibility to antifungal drugs of Candida species in blood cultures. Material and methods: A retrospective, observational and descriptive study was done at General Hospital Dr. Manuel Gea González from January 2008 to December 2009. We reviewed the clinical records of the 15 hospitalized patients in whom a positive blood culture was reported and performed antifungal susceptibility to drugs using two methods: broth microdilution M27-A3 CSLI and Fungitest. Results: The most commonly isolated species were C. parapsilosis (59%), Candida spp (18%), C. albicans (9%) and C. glabrata (13.6%). With Fungitest we observed a general susceptibility to ketoconazole, fluconazole, and amphotericin B of 100%, for miconazole and itraconazole 33% and 67% with an intermediate sensitivity. In the middle of both microdilution susceptibility was generally reported for amphotericin B and caspofungin of 100%, fluconazole 90%, voriconazole 80% and 10% dose-dependent sensitivity, itraconazole 70%, ketoconazole 50% and anidulafungin 40%. Conclusions: In the last two decades an emergence of Candida non-albicans species has been observed. It is mandatory to know the different antifungal susceptibility patterns in order to reduce the morbidity and mortality rate in critically ill patients. [ABSTRACT FROM AUTHOR]

Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)