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Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The virulence of 12 Listeria monocytogenes strains from goat and goat by-products was evaluated. Variable virulence levels were found when compared the relative virulence (mortality, %) and the ability to grow infect the spleen of BALB/c mice inoculated intravenously or intragastrically. Two strains from feed produced 100 % mortality, by either inoculation route and seven strains, including those from feed, infected the spleen with both inoculation routes. A strain inoculated intravenously without causing death in the mice produced spleen counts similar to those obtained in dead mice, this could indicate that a high count of the microorganism in the spleen not necessarily ensures its virulence. We also tested the capacity to infect J774 macrophages and Caco-2 epithelial cells, finding higher invasion and intracellular growth in Caco-2 with respect the macrophages and showing quadratic growth kinetics in both cell lines. Only the two feed strains did not show a significant difference from the control strain (P>0.05) regarding kinetic parameters and invasion percentage in both cell lines. Although all isolates were able to invade Caco-2 cells, not all isolates were able to invade the spleen after the intragastrically inoculation. Two goats feed strains were the most virulent, representing a risk for animal and human health. [ABSTRACT FROM AUTHOR]

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)