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This study examines the determinants that influence in the well-being of the inhabitants of two communes with opposite socioeconomic strata, such as the commune of Las Condes and Pedro Aguirre Cerda, both located in Chile in order to show what their discrepancies are. A survey was created and applied to the inhabitants of both communes, carrying out a descriptive analysis, there being enough evidence to reject the homogeneity of the responses. Subsequently, an estimation was made by Ordinary Least Squares (OLS), the results of which suggest that for the Las Condes commune, the determinants that positively and significantly influence the well-being of its inhabitants are safety, green areas, a greater number of family members and being employed, nevertheless the variables travelling time and poor perceived health are significant and negatively influence well-being. For the Pedro Aguirre Cerda commune, the results suggest that the determinants that significantly and positively influence the well-being of its inhabitants are security, satisfaction with the commune where they reside and being older, while the variables of poor perceived health and a greater number of family members are significant and negatively influence the well-being of inhabitants of their commune. It is hoped to contribute to public policy decision-making to maximize the well-being of people in society. [ABSTRACT FROM AUTHOR]

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