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1. [Underlying dysbiosis may be the cause of some forms of IBS. Patients were free of symptoms after the administration of microbiota].

Author

Benno P, Befrits R, Berstad A, Dahlgren AL, Norin E, and Midtvedt T

Subjects
Adult, Biological Therapy methods, Feces microbiology, Female, Humans, Male, Microbiota, Transplantation methods, Dysbiosis complications, Irritable Bowel Syndrome microbiology
Abstract

Two cases of post-infectious IBS were successfully treated with transplantation of an anaerobic cultivated human intestinal microbiota. This suggests that a dysbiosis of the intestinal microbiota could be the culprit at least in some cases of IBS. Resetting the gut microbiota might be a possible solution for these patients that otherwise may face a life-long reduction in quality of life. Studies have suggested that conditions as varied as chronic constipation, metabolic syndrome, autoimmunity, asthma, cardiovascular disease and Crohn's disease may be caused by intestinal dysbiosis. If this is the case we would like to suggest a new term: Dysbiotic Bowel Syndrome (DBS).

Published
2015

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