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Introductıon: Congenital diaphragmatic hernia (CDH) is a rare abnormality with high mortality and long-term comorbid conditions. Our aim, in this paper, was to describe demographics and birth characteristics, treatment, and outcomes of consecutive patients with CDH treated at our institution. Methods: The present study represents a retrospective cohort study of neonates with CDH who were treated at Uludag University Medical Faculty, Neonatal intensive care unit, Bursa. We identified the medical records of all patients with CDH who were admitted for treatment to our neonatal intensive care unit from January 2007 to December 2016. We reviewed the medical, surgical records, demographics and birth characteristics. We also recorded presence of pulmonary hypertension, whether or not the liver and, stomach also herniated into the thorax, other associated congenital malformations, and type of mechanical ventilation. Results: Forty patients were included in this study. The overall mortality was 67.5% (27/40). Survival for those who had surgical correction of CDH was 61% (13/21). Low birth weight, low gestational age, low APGAR scores and, high oxygen need at baseline was found to be associated with mortality, in patients with CDH. Among survivors, the median duration of hospitalization was 23 (14--35) days. Chronic gastrointestinal, pulmonary disorders and, failure to thrive were the most comorbid conditions after discharge. Dıscussıon And Conclusıon: KDH still has high mortality and morbidity. The birth of patients with prenatal diagnosis at appropriate centers will increase their chances of successful intervention. [ABSTRACT FROM AUTHOR]

In the neonatal period, upper gastrointestinal system (GIS) bleeding may be due to benign disorders which do not require any treatments or may be relevant to serious conditions requiring urgent intervention. There are two major causes of upper GIS bleeding developed in the newborns; vitamin K deficiency-induced hemorrhagic disease of the newborn and maternal blood swallowed during birth. Other causes of this type of bleeding include gastritis, esophagitis, peptic ulcus (PU), coagulopathy, sepsis, vascular malformations, trauma, and esofageal-gastric duplications. Rarely, gastric erosion or perforation due to oro/naso gastric tube might cause severe upper GIS bleeding. Hemodynamic resuscitation, bleeding control, and prevention of the recurrence form the basis of the management. However, a somatostatin analogue (ocreotide) may be helpful by reducing the splanchnic blood flow, if bleeding is caused by a known vascular lesion or arterial erosion. In this paper, a case of newborn with upper GIS bleeding developed within the first 24 hour life and probably caused by arterial erosion due to oro/gastric tube and treated by ocreotide was presented in the light of literature. [ABSTRACT FROM AUTHOR]

Although surfactant has been one of the basic treatment approaches in respiratory distress syndrome in the last 20 years, an absolute consensus has not been established regarding its way of use and dosing regimens. In this paper, a case with severe respiratory distress syndrome recovering after 5 doses of surfactant administration is presented, and multiple dose surfactant administration which is rarely required in this disease is also discussed. [ABSTRACT FROM AUTHOR]