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Our aim is to perform clinicopathological analysis of premalignant and malignant lesions of the eye and adnexa diagnosed in a tertiary clinic. The files of the patients who underwent surgery and sent specimens to pathology laboratory at Inönü University Faculty ofMedicine, Department of Ophthalmology betweenMarch 2010 and July 2020 were reviewed retrospectively. Demographic, clinical and histopathological data of cases with premalignant and malignant lesions were recorded. A total of 136 patients, 64 (47.1%) female and 72 (52.9%) male, were included in the study. The mean age of the patients was 73.6±14.7 (11-101) years. Premalignant lesions were detected in 58 patients (42.6%) and malignant lesions were detected in 78 patients (57.4%). The most common premalignant lesions were conjunctival or corneal intraepithelial neoplasia, carcinoma in situ, while the most common malignant lesions were basal cell carcinoma, squamous cell carcinoma, and lymphoma. In our clinic, the most commonly diagnosed premalignant lesion of the eyes and adnexa was conjunctival intraepithelial neoplasia, and the malignant lesion was basal cell carcinoma. [ABSTRACT FROM AUTHOR]

Background: To determine the clinical and histopathological characteristics of malignant tumors of the eyelid in terms of our region. Materials and Methods: 120 patients' files who were diagnosed with malignant eyelid tumor and followed up between January 2018 and September 2021 were scanned retrospectively in our clinic. Demographic and clinical characteristics, clinical and histopathological diagnoses, methods and follow-up results in surgical cases were recorded from the patients' files. Excisional biopsy material was obtained in all patients who underwent surgery. Results: 120 cases were included in the study. 54 (45%) of the patients were male and 66 (55%) were female. The mean age was 62.5 (35-80) years. The mean follow-up term was 20,4 months (3-36 months) for all cases. In 80% (n=96) of malignant eyelid tumors, clinical preliminary diagnosis and histopathological examination results were found to be compatible. Preoperative clinical diagnosis and postoperative histopathological diagnosis differed in 24 cases (20%). The recurrence rate was found to be 3% in all of our patients. The recurrence rates were 2% in Basal Cell Carcinoma cases and 5% in Squamous Cell Carcinoma cases. Considering the location of the tumors, 80 patients had left eyelid involvement and 40 patients had right eyelid involvement. Conclusions: Surgical excision and histopathological examination in malignant eyelid tumors are the most accurate and reliable options as they provide both diagnosis and treatment at the same time. When a malignant eyelid tumor is suspected, patients should be referred to an oculoplastic surgeon experienced in ocular oncology. [ABSTRACT FROM AUTHOR]

In this paper we classified 4 skin lesions (Melanoma, Melanocytic Nevus, Basal Cell Carcinoma, Benign keratosis) from ISIC 2019 dataset which was published by International Skin Imaging Collabration in 2019. We used InceptionV3 convolutional neural network model for classification. We applied two preprocessing methods: High Dimensional Model Representation (HDMR) and Hilbert Transform. In conclusion we obtained 89% accuracy on classification of Basal Cell Carcinoma using Hilbert Transform. Moreover, we obtained 78% accuracy on classification of Melanoma using Contrast Enhancement High Dimensional Model Representation (HDMR). [ABSTRACT FROM AUTHOR]