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In this case report, the diagnosis and treatment results of multiple congenital anomalies accompanied by coaxial agenesis, atresia ani et vulva, vaginal ectopy in a 2-day-old Simmental calf were evaluated. Our case is composed of a 2-days old simmental calf brought to our clinic with the complaint of absence of tail, anus and vulva. Clinical examination revealed tail agenesis, atresia ani et vulva. It was also detected that the calf was excreting stool and urine in the perineal region as a result of perforation of a soft fluctuant mass originating from the ectopic vagina. Histopathologic examination of the operatively removed mass revealed non-keratinized multilayer squamous epithelium consistent with vaginal mucosa. As a result, we think that this case, which is quite interesting, will contribute to clinical pract ice and literature. [ABSTRACT FROM AUTHOR]