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Background: We aimed to compare optic nerve elasticity and central retinal artery resistive index values in Nonproliferative diabetic retinopathy and Proliferative diabetic retinopathy. Materials and Methods: The degree of optic nerve hardness of 31 patients with nonproliferative diabetic retinopathy and proliferative diabetic retinopathy was evaluated using the Shear-Wave Elastography technique. Simultaneously, the resistive index values of the central retinal artery were measured using Color Doppler Ultrasonography and compared with the control group. Results: Optic nerve Shear-Wave Elastography values were significantly higher in patients with retinopathy compared to healthy volunteers and diabetic patients without retinopathy(p<0.05). Central retinal artery resistive index values were significantly higher in patients with retinopathy than those without retinopathy (p <0.05). RI values were measured as 0.57 ± 0.88 for those without retinopathy and as 0.67 ± 0.53 for those with retinopathy. Conclusions: The etiopathogenesis diabetic retinopathy is still controversial. Significant changes in the degree of stiffness of the optic nerve and ocular blood flow parameters in Color Doppler Ultrasonography examination can be observed in Nonproliferative diabetic retinopathy and Proliferative diabetic retinopathy with Shear Wave Elastography. [ABSTRACT FROM AUTHOR]

INTRODUCTION[|]This study was designed to evaluate hemodynamic alterations in the retrobulbar blood flow in primary open-angle and normal-tension glaucoma patients using Doppler ultrasonography (US) and to emphasize the importance of diagnostic imaging and vascular factors in the etiology.[¤]METHODS[|]A total of 98 eyes of 50 patients were examined for the study. The control group consisted of 14 normal cases. The patient groups were comprised of 25 patients with primary open-angle and 11 patients with normal-tension glaucoma. All of the examinations were performed using a multifrequency (5-7.5-10 MHz) linear transducer and a Toshiba PowerVision 7000 SSA-380A color Doppler US device (Toshiba Corp., Tokyo, Japan). The peak systolic velocity and resistive index values of the ophthalmic artery, central retinal artery, and temporal posterior ciliary arteries were examined.[¤]RESULTS[|]There was no significant difference between the groups in terms of age and gender distribution, and no difference in peak systolic velocity or resistive index between the 2 eyes. In both glaucoma groups, the peak systolic velocity and resistive index of the ophthalmic artery and the peak systolic velocity in the central retinal artery showed no statistically significant difference with those of the control group. The resistive index of the central retinal artery was higher in the glaucoma patients compared with the control group. In the posterior ciliary arteries, the peak systolic velocity was lower and the resistive index was higher in the glaucoma group than in the control group. No statistically significant difference was found between the 2 glaucoma groups in any parameter.[¤]DISCUSSION AND CONCLUSION[|]The findings in the central retinal artery, and especially in the posterior ciliary arteries, support the theory that changes in vascular hemodynamics can play a role in the etiology of glaucoma. Color Doppler US is a safe, noninvasive, contrast-free, radiation-free, and reproducible method to evaluate retrobulbar blood flow.[¤]