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Today, unemployment is an important problem for almost all countries and is one of the major problems affecting countries economically. The purpose of this study is put forward the relationship between unemployment and inflation in D8 (Turkey, Iran, Pakistan, Bangladesh, Malaysia, Indonesia, Egypt, Nigeria) countries within the framework of the Phillips Curve Theory. For this purpose, unemployment and inflation data of the study covers the period between 1996 and 2020. In this study, dynamic panel data regression analysis was used. As a result of the study, statistically significant and negative results were determined in the lagged values of the dependent variable and the lagged values of the unemployment rate. Thus, the existence of a negative relationship between inflation and unemployment has been revealed and Phillips curve hypothesis confirm the statistically significant results.