The problem of harmonic wave propagation in prestressed or stress free elastic or viscoelastic tubes filled or not filled with a viscous or an ideal fluid, became an interesting subject since the time of Thomas Young (1773-1829) who first obtained the speed of the pulse wave in arteries, and found important applications in many fields of engineering. The historical evolution of the subject can be found in the papers by Lambossy (1951) and Skalak (1966) and in the book by Fung (1984). In the present work, the problem that we consider is to investigate the pulsating wave propagation in large blood vessels. The importance of the present problem from the bioengineering point of view is that the wave speed and the transmission coefficient depend on the initial deformation and the material coefficients. The measurement of these parameters makes it possible to observe the variation of them with material properties. For the historical evolution of the subject the reader may refer to Morgan and Kiely (1954), Womersley (1957) who used the theory of small deformations, Atabek and Lew (1966) who were the first to introduce the effect of prestress, Mirsky (1967) who took into account the orthotropic properties of the arterial wall, Rachev (1980), Kuiken (1984) and Nayfeh (1966) who considered the blood as a two phase system consisting of plasma and blood cells and investigated the flow of the two phase flow in a rigid tube. The fluid (blood) is taken as incompressible and viscous with dusty particles in it, and the governing equations of motion are obtained in the cylindrical coordinates. On the other hand, to obtain the equations of motion of the tube (artery) which is assumed to have elastic, fibrous and incompressible material, the theory of "superimposing small deformations on large static deformations" is employed and, the incremental equations of motion and incremental constitutive equations that characterize the arisen dynamical state are given. These equations are expressed in the cylindrical coordinates and the boundary conditions to be satisfied are given. Then, assuming that the cylindrical shell (artery) is under the effect of both constant, axial stretch and inner pressure (initial equilibrium state), the incremental equations of the motion are given for this prestressed state. The solutions of these incremental equations of motion both for fluid and solid phases are obtained for the axial symmetric motion. The closed form solutions to the differential equations of the fluid were accomplished but, because the coefficients of the field equations are complex functions of the radial coordinate, it could not be accomplished to obtain closed solutions to the equations of the solid phase. For this reason and to obtain the effect of the tube's thickness on the wave characteristics, numerical solutions with method of finite differences are sought to the equations and the corresponding boundary conditions that govern the solid phase. Then, in the long wave approximation, assuming that the thin tube filled with a non-viscous fluid is non prestressed, the dispersion relation is investigated, wave speeds and transmission coefficients are obtained. As the last, again in the long wave approximation, the dispersion relation for the thick walled prestressed elastic tube filled with a viscous fluid is obtained, the wave velocities and the transmission coefficients are computed and the results are given with graphs. The obtained results are in agreement with the results of Ercengiz (2005) and Nag and Jana (1981). The obtained results reveal that the primary and the secondary wave speeds become higher with the increase of the fibre parameter of the tube's elastic material. On the other hand, the increase of the mass concentration of the dusty particles in the fluid decreases the primary wave velocity though only for the small values of the Womersley parameter, again decreases the secondary wave speed for all the values of the Womersley parameter. With the increase of the fiber parameter, while transmission coefficient for the primary wave increases, the transmission coefficient for the secondary wave decreases. The increase of the mass concentration of the dusty particles in the fluid decreases the transmission coefficients of both the primary and the secondary waves. The increase of the axial stretch increases the primary wave speed, but decreases the secondary wave speed and the transmission coefficient for the primary wave. The variation of the axial stretch doesn't change the transmission coefficient for the secondary wave. [ABSTRACT FROM AUTHOR]