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Copyright of Afyon Kocatepe University Journal of Science & Engineering / Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi is the property of Afyon Kocatepe University, Faculty of Science & Literature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study was planned to create an alternative use for orange peel, which is one of the most important fruit wastes within the scope of waste utilization. In the study, firstly, orange peel extracts were prepared by ultrasonic assisted extraction using different types of deep eutectic solvents in the green solvent category that can be alternative to organic solvents and the bioactive compound contents of these extracts were evaluated. As a result, it was determined that deep eutectic solvents were statistically effective in providing the highest total flavonoid compound and antioxidant activity values. In addition, when the individual phenolic compound profile was examined, the most dominant component was hesperidin and the highest value was reached with choline chloride:glycerol (1:2) combination. In conclusion, it was determined that deep eutectic solvents can be an alternative to organic solvents in the extraction of phytochemical compounds from orange peel. [ABSTRACT FROM AUTHOR]

Weeds are the plants growing where they are bot desired and are notorious yield reducers that are responsible for significant crop yield and quality losses in agricultural areas. Common poppy is one of these plants. As can be understood from the title, the purpose of this study was to test the possibility of using fruit extracts of common poppy (Papaver rhoeas L.) for the preservation of fruit quality. The experiments were conducted with apricot fruits cv. ‘Şalak’. Two different concentrations (0.5% and 2.5%) of P. rhoeas fruit extracts together with an un-treated control treatment were tested in the current work. Studies were carried out with three replications for each treatment, where each replication consisted of six individual fruits. Studies were continued for 42 days and the fruits were stored at 0.0±0.5 °C with 90-95% relative humidity. Different quality parameters of apricot fruits were measured and noted with 7-days interval. It was found that the hypothesis of current research was acceptable, where the fruit extracts of P. rhoeas were found to reduce weight loss at the apricot fruits, help to reduce disease severity, maintain visual quality of the fruits, reduce the chilling injury and fruit firmness and significantly influence the ascorbic acid content by delaying its reduction. Overall, findings of current work suggest that the P. rhoeas fruit extracts have ability to maintain postharvest quality of apricot fruits and further studies are required to determine the exact mechanism and the responsible constituents. [ABSTRACT FROM AUTHOR]

In this study, phenolic extracts of strawberry, red raspberry, sour cherry, and cornelian cherry were obtained using methanol, ethanol, 80% methanol, and 80% ethanol as extraction solvents. Total phenolic content and antioxidant activities (ferric reducing power, antioxidant activity in linoleic acid emulsion, and DPPH radical scavenging activity) were determined for each fruit extracts at different concentrations (0.5, 1, 2 and 3 mg mL-1 ). Antioxidant activities of all extracts were increased with increased concentration (P<0.05). There was a correlation between total phenol content and antioxidant activity of the extracts. According to total phenolic content and antioxidant activity analyses, strawberry extracts had significantly higher antioxidant activity compared to other fruit extracts (P<0.05). Reducing power of raspberry ethanol extract was the lowest and sour cherry had higher reducing power than cornelian cherry for the same solvent. Aqueous ethanol extracts had higher antioxidant activity in linoleic acid emulsion among fruit extracts at all concentrations. Except for strawberry extracts, 80% methanol extract of red raspberry had the highest DPPH radical scavenging activity at all the concentration tested, followed by cornelian cherry and sour cherry extracts. [ABSTRACT FROM AUTHOR]

This study aims to investigate the cytotoxic effects of Ecballium elaterium, known as squirting cucumber or exploding cucumber among the people, against some cancer cell lines. E. elaterium has been used as a drug against many diseases since the ancient Egyptians. The cytotoxic effects of fruits and leaves extracts of E. elaterium against malignant melanoma (SK-MEL-30), colon (CACO-2), breast (MCF-7), and non-small cell lung (H1299) cancerous cell lines were evaluated by the MTT test. Toxicity of the fruits and leaves extracts of E. elaterium were also tested on the mouse fibroblast cell line (L929). As a result, fruits and leaves extracts of E. elaterium showed weak cytotoxic activity against the SK-MEL-30 cell lines, while moderate cytotoxic activity against H1299 cell lines, and high cytotoxic activity against the MCF-7 cell lines. Against the CACO-2 cell line, however, it was observed that both extracts had no cytotoxic effects. Also, fruit extracts exhibited higher cytotoxic activity than leaf extracts. [ABSTRACT FROM AUTHOR]

Possible side effects of drugs used as antimicrobial agents and microorganisms' resistance to these drugs pose a great danger to human health. This situation led to the scientific community to new searches. It is known that many herbal products consumed as food are also used by the public for the protection of diseases. However, many of these are still not confirmed by scientific data. In this regard, in the current study, Morus nigra L. (black mulberry) fresh fruit extracts (ethanol, methanol and ethyl acetate) collected from Elazığ province and used by local people to alleviate many diseases, total antioxidant content of total phenolic and total flavonoids capacities were determined. However, the phytochemical content of the ethanol extract was evaluated by RP-HPLC. In addition, their antimicrobial properties and synergies with antibiotics (chloramphenicol, novobiosin and nalidixic acid) were tested. The total phenolic content value and antioxidant properties of ethanol extract were significantly higher than the others. The major component of this extract was determined as chlorogenic acid. It was determined that the extracts showed low efficacy against the test microorganisms, however, all extract antibiotic mixtures exhibited a full synergistic effect on P. aeroginosa, a serious pathogen, except for the methanol extract / chloramphenicol combination. The full synergy is important in terms of ensuring that the antibiotic is more effective at a lower dose. As a result, due to the biological activities of M. nigra fruit extracts, it is thought to have the potential to be used as a natural and alternative source in the food and pharmaceutical industries. [ABSTRACT FROM AUTHOR]

This study was carried out to determine the antioxidant and antidiabetic activities of Elaeagnus angustifolia L. (oleaster) fruits and leaves. The total phenolic, total flavonoid and tannin contents, antioxidant activities (DPPH and ABTS methods), and inhibitory effects against α-glucosidase and α-amylase enzyme were investigated in the oleaster fruit and leaf extracts obtained with methanol: water (1:1, v/v). In addition, lipase inhibition activity was determined in these extracts. The values in which the fruit and leaves of oleaster inhibit the α-glucosidase enzyme by 50% (IC50) were determined as 17.11 μg/mL and 124.71 μg/L, respectively. Neither fruits nor leaves displayed a lipase inhibition activity. In terms of the phenolic, flavonoid and tannin contents and antioxidant activity values of the extracts of fruits and leaves, the bioactive content of fruits was significantly higher than that of leaves (p<0.05). Considering in vitro antidiabetic activities of the fruits and leaves of oleaster, the consumption of these natural extracts may have a potential for the treatment of type 2 diabetes. [ABSTRACT FROM AUTHOR]