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Hypoparathyroidism is a rare clinical condition characterized by parathyroid hormone insufficiency, decreased serum calcium, and increased serum phosphorus levels. Neck surgery is the most common cause of acquired hypoparathyroidism in adults. Post-surgical hypoparathyroidism is reported as one of the important complications in thyroid gland surgeries and if not diagnosed timely, may be associated with severe morbidity. The clinical manifestations of hypoparathyroidism are variable and may affect almost all organ systems. It is usually manifested by symptoms associated with hypocalcemia. The most common symptom is neuromuscular irritability, which includes paresthesias and muscle spasms in hands, feet, and around mouth. Rarely, some cases may present with inflammatory low back and neck pain, widespread pain, posture disorders, muscle weakness or, limited vertebral range of motion in the long term. Some patients may be misdiagnosed as spondyloarthropathy and may receive unnecessary treatments. In this case report, we present the clinical findings of a 55-year-old male patient with delayed post-surgical hypoparathyroidism who had been previously diagnosed ankylosing spondylitis and referred to our clinics for further treatment.

Amaç: Egzersiz tedavisi, kronik non-spesifik bel ağrısı (NSKBA) tanısı alan hastalarda en yaygın önerilen tedavi şeklidir. Ancak bir egzersiz yönteminin başka bir egzersiz yöntemine üstün olup olmadığı tartışmalıdır. Gereç ve Yöntem: Bu çalışmada NSKBA olan hastalar deney grubu (gözetimli aerobik egzersiz + ev egzersizi) ve kontrol grubu (sadece ev egzersizi) olmak üzere iki gruba randomize edildi. Hastalar tedavi öncesi, tedavi bitimi ve tedavi bitiminden üç ay sonra ağrı şiddeti, spinal mobilite, lomber ektansör kas dayanıklılığı, depresif semptom varlığı ve şiddeti, özürlülük ve yaşam kalitesi bakımından değerlendirildi. Bulgular: Deney grubunda tüm değerlendirmelerde anlamlı düzelme saptanırken kontrol grubunda, ağrı, spinal mobilite ve yaşam kalitesinin fiziksel komponentinde anlamlı düzelme saptandı. Kontrol grubuna göre, deney grubunda değerlendirme parametrelerinde zamanla meydana gelen olumlu değişim anlamlı olarak daha yüksekti. Sonuç: Aerobik egzersiz, NSKBA olan hastaların yetersizliklerinin düzeltmesine, aktivite düzeylerinin ve katılım düzeylerinin arttırılmasına katkı sağlayabilir. Ancak hangi aerobik egzersiz tipinin (sıklığının, süresinin ve yoğunluğunun) daha etkili olduğuna yönelik çalışmalara ihtiyaç vardır.

Spontaneous bilateral quadriceps rupture is rarely seen in systemic diseases. Although the underlying mechanism in tendon rupture is not clearly understood, β2-amyloidosis, chronic acidosis, impaired collagen metabolism, accumulation of uremic toxins and secondary hyperparathyroidism are held to be responsible. The patients with bilateral spontaneous quadriceps rupture can be able to achieve significant functional improvement with the postoperative rehabilitation program. In this article, we aimed to present a patient with hemodialysis who developed spontaneous bilateral quadriceps and unilateral triceps rupture and discuss in company with the literature.

Objective: In this study, we investigated the relationships between 10 year fracture risk calculated with FRAX assessment tool and bone turnover markers (BTM) in women with diagnosed as postmenopausal osteoporosis for the first time. Materials and Methods: After exclusion of the causes of secondary osteoporosis 61 postmenopausal women diagnosed with osteoporosis for the first time were enrolled. Height and weight measurements, comorbid diseases, menopause age, and laboratory investigations were recorded. Lumbar and femur neck and femur total T scores were measured by dual-energy x-ray absorptiometry (DXA). As BTM, serum osteocalcin (OC) and urine deoxypridinoline levels were measured. 10-year fracture risk of hip and major osteoporotic fracture was calculated with FRAX assessment tool. Results: The mean age of patients was 61±39 years. Median value of menopause year was 15.13 years (min: 2, max: 40). The median 10-year hip fracture and major osteoporotic fracture risks were calculated as 1.10% (min: 0, max: 23), 6.9% (min: 3, max: 34) respectively. There was no significant relationship between BTM and fracture risk. Positive significant correlation was found between menopause year and hip fracture risk, and between menopause year and major osteoporotic fracture risks (p=0.031, 0.276; p=0.025, r=0.287). Negative significant correlation was detected between body mass index and hip fracture risk (p=0.002, r=-0.392). Conclusion: In our study, we couldn’t find relationship between BTM and fracture risks assessed by using FRAX tool in patients with initially diagnosed of postmenopausal osteoporosis. Further studies are needed to investigate the relationship between BTM and fracture risk in different patient groups. (Turkish Journal of Osteoporosis 2015;21: 58-62)