Search

Objective: Behçet's disease (BD) is a multisystemic vasculitis affecting both gender and usually diagnosed in reproductive age. In this study, we aimed to investigate the relation between BD and pregnancy on the both maternal and fetal aspects. Methods: In this retrospective, single-center, descriptive study we analysed total 61 pregnancies of 18 BD patients. Clinical and demographic data were obtained from patients records regarding maternal age, disease histroy, obstetric history, pregnancy outcome and both maternal and fetal complicaitons. To prevent recall bias, only the recent pregnancy of each patient were evaluated for disease activity and use or revision of medicaitons during pregnancy. Results: The median age of the patients at diagnosis was 25 and first pregnancy age was 24.5 years. The median duration of BD during pregnancy was 3.5 years. Only one patient needed to in vitro fertilization to become pregnant. All patients were in remission before recent pregnancy. Fourteen (77.8%) patients had no symptoms during recent pregnancy, while remaining 3 patients had mucocutaneous and 1 patient had vascular activity. The rate of live birth was 74.1%, abortus was 20.7%, preterm labor was 11.6%, pre-eclampsia was 5.6%, and no congenital fetal abnormality was observed. Conclusion: Except for vascular complications, no major organ involvement was described during pregnancy. Higher miscarriage rates were observed compared the healthy pregnancyies. Obstetric complications were not increased and fetal outcomes were not negatively affected by BD. BD is not a contraindication for the onset of pregnancy but control of disease activity before pregnancy, revision of potentially teratogenic agents, and frequent follow-up of patients in view of potential complicaitons are important to minimize risks. [ABSTRACT FROM AUTHOR]

Copyright of Gümüshane Üniversitesi Saglik Bilimleri Dergisi is the property of Gumushane University, Faculty of Health Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: We aimed to compare the effects of placenta previa (PP) and placenta accreta (PA) on the short-term maternal morbidity alone and together. Methods: The data of the patients who were diagnosed with PP, PA or placenta previa accreta (PPA) which includes both of them between January 2010 and December 2018 in a tertiary reference center were analyzed retrospectively. The records of the patients were compared between 3 groups for age, gravida, parity, week of gestation, previous cesarean section, history of curettage and myomectomy, gestational complications, placental location, hospitalization at hospital and intensive care unit, decreased level of hemoglobin, blood product transfusions, procedures to control bleeding and complications. Results: Six out of 192 patients were excluded from the study as they delivered in other hospitals, and the data of 186 patients were analyzed. There were 141 (75.8%) patients with PP only, 9 (4.8%) patients with PA only, and 36 (19.4%) patients with PPA. The erythrocyte transfusion was significantly higher in PPA patients than PP patients (p<0.001). The possibility for the transfusion of any blood product was lower in PP group than other groups. While the rate of hospitalization at intensive care unit was higher in PPA group, the number of hospitalization day at hospital was significantly lower in PP group than PA (p=0.042) and PPA (p<0.001) groups. Urinary complication was observed less in PP patients. The hysterectomy rate was higher in PPA patients with than PP and PA patients (p=0.004). Conclusion: The rates of maternal morbidity and hysterectomy increase when PP and PA are together compared to the cases where they are alone. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Ankara University Faculty of Medicine / Ankara Üniversitesi Tip Fakültesi Mecmuasi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)