Search

Introduction: Suppression of tumorigenicity 2 (ST2) plays a key role in the serious complications that may occur during Coronavirus disease-2019 (COVID-19), including systemic inflammatory condition, sepsis, Acute respiratory distress syndrome, and fibrosis. In this study, we evaluated the relationship between the serum ST2 concentrations and the mortality and need for mechanical ventilation. Materials and Methods: A prospective observational study was conducted in patients diagnosed with COVID-19 who presented to the emergency department (ED) between October 2021 and April 2022. Patients with Severe acute respiratory syndrome-Coronavirus-2 infection were consecutively enrolled according to the clinical spectrum defined in the guidelines. Admission to the intensive care unit (ICU), requirement of intubation, and 90-day mortality were the primary study outcomes. Clinical, imaging and laboratory data were assessed to determine the clinical spectrum and severity scores. ST2 was assessed using the micro ELISA method and Sandwich-ELISA principle. Results: Of the 64 (48.5%) patients admitted to the ICU, 43 (32.6%) required mechanical ventilation. During the 90-day follow-up period, 44 (33.3%) patients died due to clinical deterioration. The median ST2 concentration at admission was 272.5 ng/mL in patients who died and 55.95 ng/mL in patients who survived (p

Objective: Upper gastrointestinal system (UGIS) bleeding is a life-threatening abdominal emergency. Numerous scoring systems have been developed to identify patients who may develop mortality due to UGIS bleeding. We aimed to determine the effectiveness of the Glasgow Blatchford Score (GBS), Rockall score (RS), and AIMS 65 score in predicting the length of hospital stay, re-bleeding, and transfusion need. Material and Methods: It was carried out retrospectively by recording the parameters and clinical scoring systems collected from the archive files and epicrisis information of the patients with the pre-diagnosis of UGIS hemorrhage. Results: Sixty-three (67.7%) of 93 patients were male. Four patients (4.3%) needed intensive care, and in-hospital mortality occurred in 4 (4.3%) patients. Mortality was observed in 7 patients (7.5%), and recurrent UGIS bleeding was observed in six patients (6.5%). A statistically significant difference was found in AIMS 65 and Rockall scores in predicting -intensive care needs (p

Amaç: Bu klinik çalışmada amaç pulmoner tromboemboli tanısı alan hastalarda ortalama trombosit hacmi ile emboli yükünün ilişkisini ortaya koymaktır.Gereç ve Yöntem: Bu retrospektif çalışmaya pulmoner emboli tanısı alan 120 hasta dahil edildi. Hastaların ortalama trombosit hacmi, Troponin-I, D-dimer değerleri, arter kan gazları, göğüs radyografisi, elektrokardiyografi, ekokardiyografi ve venöz doppler ultrason bulguları kaydedildi. Ayrıca bilgisayarlı tomografi anjiyografi kullanılarak pulmoner arteriyel obstrüksiyon indeksi hesaplandı.Bulgular: Ortalama trombosit hacmi ile pulmoner arter basıncı arasında ve pulmoner arteriyel obstrüksiyon indeksi arasında pozitif korelasyon tespit edildi. Ortalama trombosit hacmi < 8.5fl olan ve > 8.5fl olan gruplar arasında pulmoner arter obstrüksiyon indeksi açısından istatistiksel anlamlı bir fark tespit edildi (25.0 and 45.0). Ortalama trombosit hacmi > 8.5fl olan olan grupta pulmoner arter basıncı < 8.5fl olan gruptan istatistiksel anlamlı olarak yüksek bulundu.Sonuç: Pulmoner arteriyel bilgisayarlı tomografi obstrüksiyon indeksi ile ortalama trombosit hacmi arasındaki korelasyonun pulmoner embolizm şiddetini belirlemedeki değeri net değildir.