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Copyright of SDU Journal of Engineering Sciences & Design / Mühendislik Bilimleri ve Tasarım Dergisi is the property of Journal of Engineering Sciences & Design and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this study, a new disposable label-free immunosensor was developed for the electrochemical determination of alpha-fetoprotein (AFP) that is a cancer biomarker and its application was performed on human blood serum samples. In the work, firstly the screen printed carbon electrodes (SPCE) were modified with reduced graphene oxide (RGO), then the electrode surface was coated with polyneutral red (PNR) by applying the electropolymerization technique and finally, gold nanoparticles (AuNP) were created by electrodeposition method on the surface. Electrochemical characterizations of the SPCE/RGO/PNR/AuNP electrode were performed using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and square wave voltammetry (SWV) methods. Immobilization of Anti-AFP to the surface of SPCE/RGO/PNR/AuNP electrodes was carried out by a covalent binding method using 3-mercaptopropionic acid (3-MPA) and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-hydroxysuccinimide (EDC/NHS). The optimum working parameters of the prepared AFP immunosensor were determined by DPV and SWV methods. It was calculated that the linear range was 1-500 ng mL-1, the limit of detections was 0.79 ng mL-1, and 0.86 ng mL1, respectively. The reproducibility of the AFP immunosensor was tested for 50 ng mL-1 AFP concentration and relative standard deviation (R.S.D.) values were calculated as 4.06% (n = 10) and 3.68% (n = 10) for DPV and SWV methods, respectively. The operation stability of the developed AFP immunosensor was examined by voltammetric methods for 60 days, and the storage stability for 12 weeks. The prepared AFP immunosensors were used for the analysis of different concentrations of AFP added to the human serum samples in a known amount and over 95% recoveries were obtained. [ABSTRACT FROM AUTHOR]

Copyright of Art-E is the property of Suleyman Demirel University, Faculty of Fine Arts and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study was conducted to investigate printing techniques used in electronic textile applications and to examine the application conditions, advantages and disadvantages of the conductive inks used in these printing processes. This research is a conceptual framework designed to examine conductive inks within the scope of electronic textiles and their importance. In the study, it is seen that by printing of silver doped conductive ink on flexible materials, radio frequency identification (RFID, electromyography (EMG) and variety of sensors are designed. It was evaluated that screen printing and inkjet printing techniques are most familiar printing applications. [ABSTRACT FROM AUTHOR]