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Objective: In the last decade, intravenous drug use (IVDU)-associated infections have increased significantly in parallel with the increase in intravenous drug addiction. Skin and soft tissue infections (SSTIs) and infective endocarditis (IE) are the most common infections and are important causes of morbidity and mortality. We aimed to share our experience regarding the epidemiology, microbiology, diagnosis, and management of IVDU-associated infections. Methots: Patients hospitalized with IVDU-associated bacterial infections between January 2014 and December 2023 were included in this descriptive and retrospective study. Results: Seventy-three IVDU-associated infections were identified in 66 patients. The median age was 30.5±7.23 years, and 90.9% were male; 35 (47.9%) were SSTI, 29 (39.7%) IE, 3 (4.1%) pneumonia, and one patient each (1.3%) had acute hepatitis B and brain abscess. Four (5.4%) had both SSTI and IE. Chronic hepatitis C (83.3%) was the most common viral infection. 24.2% of them had deep vein thrombosis. The leg (33.3%) and forearm (20.5%) were the most frequently affected areas in SSTI, and 19 (48.7%) were abscesses, 14 (35.9%) cellulitis, 5 (12.8%) necrotizing SSTIs and one septic arthritis. Osteomyelitis was observed in 8 (20.5%) of the SSTIs. Half (51.2%) of the SSTI patients underwent surgical intervention. Blood cultures were taken from 82% (n=32) of 39 SSTIs, and bacteremia was detected in 37.5% (n=12). Microorganisms were identified in 84% (n=21) of 25 abscesses; four were polymicrobial. Of 33 IE patients, 84.8% had right-sided IE. The tricuspid valve (96.4%) was most commonly involved; septic pulmonary embolism was documented in 20 (71.4%) of the patients. Valve surgery was performed in nine of the patients (27.2%). Methicillin susceptible Staphylococcus aureus was the most common pathogen (35.7%), followed by methicillin-resistant S. aureus (22.8%). The mortality rate was 9%. Conclusion: Increase in IVDU is an urgent public problem for our country. Multidisciplinary approach and antimicrobial treatment are essential in the treatment of IVDU associated-SSTI and IE. [ABSTRACT FROM AUTHOR]

Copyright of International Journal of Engineering Research & Development (IJERAD) is the property of International Journal of Engineering Research & Development and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Türk Radyoloji Seminerleri is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Türk Radyoloji Seminerleri is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Pasteurella multocida is a gram-negative, non-motile, oxidase positive, catalase positive, indole positive, urease negative, non-spore-forming coccobacillus. Animal bites, scratching, and licking are the most critical risk factors for Pasteurella infections, but it may also occur without any contact. Data about the prevalence of these infections in Turkey is limited because most cases apply to primary healthcare institutions where bacterial culture cannot be performed, and infections are treated empirically. This report aims to analyze a soft-tissue infection caused by P. multocida following an animal bite and is reported for the first time from Konya. [ABSTRACT FROM AUTHOR]

Pasteurella multocida (PM) is a gram negative coccobacillus which is frequently isolated from oropharyngeal secretions of domestic animals such as cats and dogs. For typical isolates from propable sources such as cat bite or scratch, the presence of indolepositive and oxidase-positive, gram-negative bacilli, non-growing on MacConkey agar, is usually sufficient for identification of Pasteurella multocida. Both animal bites and scratches typically cause soft tissue infections which tend to have favorable outcomes with appropriate medical treatment, however, they may also cause serious clinical conditions such as osteomyelitis, pneumonia, endocarditis, sepsis and meningitis. In this article, a case of soft tissue infection due to Pasteurella multocida in a 61 year-old diabetic female who had a history of dog bite on her left leg, was presented in the light of the literature. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was detect to infection source before the bloodstream infection (BSI) of patients with secondary BSI to examine the epidemiological features, sources of infection, prognosis and antibiotic resistance. Materials and Methods: Culture/antibiotic susceptibility results of all hospitalized patients were evaluated retrospectively. Age, gender, localization of infection, causative microorganism, antibiogram test results, time frame between primary and secondary BSI and prognosis of each patients with secondary BSI was investigated. Results: In a total of 1,584 patients, secondary BSI was detected in 200 patients, 158 (79%) of them in the intensive care unit and 42 (21%) of inpatient services. Median of time between primary and secondary bloodstream infections among specimen species were statistically insignificant (p=0.091). Urinary tract infection (37%) is the most common, followed by respiratory tract infections (31%), skin and soft tissue infections (18%), central nervous system infections (10%) and other infections (4%). Acinetobacter baumannii complex species had a resistance against more than 95% of antibiotics except aminoglycosides. Resistance to carbapenem group antibiotics was observed at a rate of 2% in Escherichia coli strains and the rate was found to be 35% in Klebsiella pneumoniae isolates. Methicillin resistance was found in 29% of Staphylococcus aureus and 90% of coagulase negative staphylococci and 25% of Enterococcus spp. were resistant to vancomycin. Conclusion: Knowing a source of infection in secondary bloodstream infections will lead to an identification of risk factors for infections and a description of infection control practices. It will reduce health expenditure as well as mortality rate.. [ABSTRACT FROM AUTHOR]

Objective: Acinetobacter baumannii is clinically important, especially in critically ill patients, due to the infections it may cause. In our study, it was aimed to evaluate the A. baumannii strains which were detected as a healthcare-associated infection agent (HCAI) in a tertiary hospital. Material and Method: Nine hundred and forty patients hospitalized in the intensive care unit were followed prospectively in terms of HCAIs by active surveillance method. The "Centers for Disease Control and Prevention" (CDC) diagnostic criteria were used for the diagnosis of HCAIs. A total of 947 A. baumannii strains isolated from clinical specimens of patients diagnosed as HCAIs were analyzed retrospectively. Results: Nine hundred forty-seven A. baumannii strains isolated from the cultures of patients and diagnosed as HCAIs were included in our study. The most common infection of A. Baumannii was lung infection (57.1%). This was followed by soft tissue infection (STI) (28.7%), surgical site infection (SSI) (13.4%), bloodstream infection (BSI) (13.05%) and urinary system infection (UTI) (5%). Considering the distribution of A. Baumannii as causative agent in invasive device related hospital infections, it was considered as responsible in 67% of VAP, 13.2% of central venous catheter related bloodstream infections (CVCR-BSI), 6.1% of catheter-related urinary system infection (CI-UTI). The units where A. baumannii was found most frequently were ICUs (87%). Conclusion: By observing the distribution of A. baumannii according to the systems in by the patients which were hospitalized in our hospital, it was found that respiratory tract infections were most common. Determination of resistant A. Baumannii isolates and the risk of cross contamination in the hospital environment is important in terms of evaluating the effectiveness of the control measures being applied and developing more effective methods. [ABSTRACT FROM AUTHOR]

Objective: Infection is one of the common reasons requiring hospitalization in geriatric patients. In this study, it was aimed to investigate the epidemiology, clinical and laboratory findings, and factors affecting mortality in inpatient geriatric infections. Methods: Patients aged =65, who were followed up in the infectious diseases ward of the 500-bed training and research hospital, between January 2016 and December 2018, were included in the study. Demographic data such as age, sex, comorbidity, number of drugs used, source of infection of the patients were recorded. Clinical and laboratory data of the survivors and nonsurvivors, and results of the cultures were recorded. Factors affecting mortality were also evaluated. Results: Two hundred and five patients were included in the study. The mean age of the patients was 75.06 ± 7.33 and 117 (57%) of them were female. Fifty six (27.3%) of the infections were healthcare releated. Ninety-five percent of the patients had at least one comorbidity. The most common comorbidities were hypertension, malignancy, diabetes mellitus, and coronary artery disease. Eigthy-six point five percent of the patients were using at least one drug. The mean number of drugs used by the patients was 3.8 ± 2.86. The most common diagnoses of the patients were pneumonia (37%), urinary system infection (30.7%), and soft tissue infection (19.5%). Forty-nine point seven percent of the patients had used antibiotics and 35.6% had been hospitalized at least once during the last three months Chronic kidney failure, healthcare-associated infection, a need to change in the initial antibiotic treatment and the need for intensive care were found to be risk factors for mortality. Conclusion: Physiological effects of aging and comorbidities predispose to infection in elderly patients, resulting with frequent antibiotic use and hospitalization. Infections with resistant microorganisms and drug-drug interactions due to multiple drug use should be taken into consideration in empirical antibiotic treatment of these patients. [ABSTRACT FROM AUTHOR]

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis that can affect all organs and tissues. The clinical forms of primary cutaneous tuberculosis are tuberculosis primary complex (tuberculosis chancre) and tuberculosis cutis miliaris (miliary cutaneous tuberculosis). Secondary cutaneous tuberculosis includes lupus vulgaris, tuberculosis cutis verrucosa, scrofuloderma, tuberculosis cutis orificialis, and metastatic tubercular abscesses. The most common form is lupus vulgaris. Cutaneous tuberculosis is a rare form of tuberculosis presenting with nonspecific lesions. It is difficult to diagnose due to its non-spesific clinical characteristics thus it can be confused with many other diseases. In this paper, we reviewed five patients with cutaneous tuberculosis who presented to our clinic within the past one year and we aimed to emphasize that cutaneous tuberculosis can manifest in different clinical forms. [ABSTRACT FROM AUTHOR]

Skin and soft tissue infections (SSTIs) can be seen in a variety of clinical features, from mild infection to life-threatening serious necrotizing infections. Etiology of SSTIs vary according to geographical characteristics, patient's immunity, and risk factors. In recent years, complicated SSTIs are more frequent due to increase in the elderly and immunosuppressed patient population. Management of these infections becomes more difficult with the increase of resistant microorganisms. In this review article, SSTIs, both complicated and non-complicated, were classified on the basis of clinical view and patient characteristics, and recent changes related to diagnosis and treatment were reviewed in accordance with the recommendations of international guidelines. In addition, infectious diseases such as anthrax and tularemia were briefly outlined, of which epidemiological studies in Turkey are performed. [ABSTRACT FROM AUTHOR]

Objective: Staphylococcus aureus can cause severe community and healthcare-related infections such as skin and soft tissue infection, urinary system infection, endocarditis, pneumonia, septic arthritis, osteomyelitis, and sepsis. Also, it has high morbidity and mortality rates. In our study, we aimed to determine the resistance rates of methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) isolates to antimicrobials and to examine the resistance profile of our hospital. Material and Method: Eight hundred and seventy nine S. aureus samples isolated between 2018 and 2019 were included in the study. The isolates were identified by conventional methods and MALDI-TOF MS (Bio Merieux, France). The antimicrobial susceptibility tests of the isolates were determined by the Kirby-Bauer disc diffusion and Gradient diffusion method as suggested by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guideline. Results: The average rate of MRSA in the two years was 23.3% and the ratio was 24.2% and 22.3% in 2018 and 2019, respectively. Wound cultures were found to be the most frequently isolated clinical sample. No resistance to vancomycin and linezolid was detected in MRSA and MSSA isolates. The highest resistance rates were detected against penicillin in 98% and 82.8% of MRSA and MSSA strains, respectively. Conclusion: To know the resistance profiles of S. aureus isolates isolated from patients admitted to our hospital; it will guide the empirical treatment. It will also contribute to the control and management of MRSA with effective infection control measures and selective reporting of antimicrobial susceptibility administration. [ABSTRACT FROM AUTHOR]

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) which is the most common cause of skin and soft tissue infections and necrotizing pneumonia can also lead to many clinical condition. Trauma causing disruption of skin barrier integrity, intravenous drug use, living in crowded environments such as prison/dormitory/nursing home, low socioeconomic status, nasal S. aureus carriage, presence of health workers in the family, history of hospital admission and recent use of antibiotics are the most important risk factors. Panton-Valentine leukocidin is a cytotoxin which is found especially in the CA-MRSA strains. The infection is aggravated by Panton-Valentine leukocidin (PVL) which causes lytic pores in leukocytes. Strains which contain PVL are found to be associated with tissue necrosis and abscess formation. CA-MRSA strains contain staphylococcal chromosomal cassette (SCC)mec type IV or V gene cassette, so resistance is seen only against β-lactam group antibiotics. In this report, we present two cases of severe skin and soft tissue infections caused by CA-MRSA. Both patients who had risk factors for CA-MRSA underwent surgical drainage and debridement. Methicillin-resistant S. aureus strains isolated from the patients were positive for SCCmec type IV and PVL. In general, β-lactam antibiotics are preferred in the treatment of community-acquired skin and soft tissue infections. Because of the increasing in CA-MRSA incidence, the risk factors for CA-MRSA should be evaluated in patients and the empirical treatment should be planned accordingly. [ABSTRACT FROM AUTHOR]

Aim: We aimed to evaluate the prevalence and characteristics of infections, presence of fever and parameters affecting length of hospital stay in hospitalized older adults. Methods: The study included 188 patients aged 65 years and over who were hospitalized in 2017. Demographic characteristics of patients, focus of infection, fever, admission and peak levels of acute phase reactants, culture results, antibiotics used, length of stay and comorbidities were determined. Results: The mean age of the patients was 80±7.9 years and 58% were female. Infection was detected in 53.5% (n=107). Infection was present on admission in 70 patients (65.4%). The most common infections were urinary tract (57.9%), respiratory tract (44.9%), skin and soft tissue infections (10.3%). Fever was present in 44.9%; 89.5% was detected 48 hours after admission. Peak CRP value was found to be the most common parameter that prolonged the hospital stay. Conclusion: For older adults, one of the main causes of hospitalization is infections. Infections prolong the length of hospital stay; so, they should always be taken seriously in older adults, even if there are no typical clinical and laboratory findings. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Tepecik Education & Research Hospital / İzmir Tepecik Eğitim ve Araştırma Hastanesi Dergisi is the property of Logos Medical Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: This study was conducted to investigate cases of methicillin-resistant Staphylococcus aureus (MRSA) infections and also to draw attention to community-acquired MRSA in patients hospitalized at our Pediatric Clinics. METHODS: The patients who had meaningful S. aureus growth in the cultures taken from the patients who were hospitalized in Uludag University Medical Faculty Children's Health and Diseases Clinics between October 2012-February 2017 were included in the study. SPSS 17.0 program was used for statistical analysis. RESULTS: A total of 31 S. aureus infections were detected during this period. Seventeen (54.8%) of the cases with S. aureus infection were health care related. Methicillin-resistant S. aureus was present in 12 (70.5%) of the healthcare-acquired staphylococcal infections. Methicillin-resistant S. aureus was detected in 12 (85.7%) of 14 community-acquired staphylococcal infections. Eighty-three percent (n=10) of community-acquired MRSA infections were male and their mean age was 67.6 ± 77.8 months (median 26, range 1-204). Sixty-seven percent (n=8) of healthcare-acquired MRSA (HAMRSA) were male and their mean age was 106.7±81.3 months (median 108, range 0-222). Most of the community-acquired MRSA patients were diagnosed with soft tissue infection. In the HA-MRSA cases, bacteraemia was the most common infection. Sixty-nine percent of the soft tissue infections originated from CA-MRSA, 73% of the other infections originating from HA-MRSA (p=0.041). MRSA associated mortality was not detected in the cases. CONCLUSIONS: Methicillin-resistant S. aureus (85.7%) was found to be high in community-acquired staphylococcal infections in our study. Most of the community-acquired MRSA was detected in patients with soft tissue infections, followed by septicemia. Bacteraemia was the most frequent healthcare-acquired MRSA infection. [ABSTRACT FROM AUTHOR]

Aim: This study was to investigate the laboratory and clinical features of patients in whom Streptococcus spp. were isolated from cultures other than throat cultures. Methods: A total of 161 Streptococcus strains isolated from clinical specimens from 101 (64%) hospitalized patients and 65 (36%) outpatients and clinical and laboratory features of patients were investigated retrospectively. Isolated Streptococcus strains were further identified for type and antibiotic susceptibility according to the Clinical and Laboratory Standards Institute guidelines. Results: Streptococcus strains types were determined as follows; group A (9-5.6%), group B (64-39.7%), group C (2-1.2%), group D (2-1.2%), group G (2-1.2%), viridans (57-32.2%), and Streptococcus pneumonia (24-14,9%). Most frequently observed infections were urinary system infections (52-32.2%), skin and soft tissue infections (48-29.8%) and pulmonary infections (25-15.5%). In 87 (54%) of patients, there was more than one comorbid condition. While all group A Streptococcus pyogenes strains were susceptible to penicillin, 13% of Streptococcus pneumonia were resistant to penicillin and 36.3% were resistant to macrolides. Mortality was observed in eight patients. Conclusion: Invasive streptococcal infections may cause serious mortality and morbidity especially in patients with comorbid conditions. Early detection and appropriate antimicrobial therapy are most important parameters for the management of streptococcal infections. [ABSTRACT FROM AUTHOR]

Arcanobacterium haemolyticum, a well-defined pathogen of pharyngitis in humans, is also isolated from ulcerative skin infections with a chronic course. Despite of its occurrence in 0.3 to 2% of the cases with pharyngitis, A. haemolyticum has never been isolated before as a causative agent of soft tissue infection in Turkey. We present the first case of diabetic foot infection caused by A. haemolyticum. Increasing awareness in clinical microbiology laboratories will likely allow us to understand the importance of these bacteria in soft tissue infections. [ABSTRACT FROM AUTHOR]

Necrotizing fasciitis is a serious soft tissue infection with rapidly spreading inflammation, thrombosis and necrosis affecting the skin, subcutaneous tissue and fasciae. The disease should be diagnosed early and appropriate antibiotherapy and surgical debridement should be applied. Delay in diagnosis or treatment significantly increases the morbidity and mortality of the disease. The aim of this report is to present a case with mortal necrotizing fasciitis in the light of the literature. [ABSTRACT FROM AUTHOR]

Skin and soft tissue infections are most commonly caused by staphylococci or streptococci. Rarely, they can develop due to bacteria of the genus Aeromonas after contact with contaminated water and soil following trauma. A 75-year-old female diabetic patient applied to the infectious diseases outpatient clinic with complaints of swelling, pain, redness, tenderness, erythema and warmth in her lower leg. The patient had a skin deformity as a result of a previous traffic accident and she had gone to thermal springs 2 weeks before. Streaking suggestive of lymphangitis, redness, bullous lesions and right lower extremity edema were noted. Leukocyte count was 18 300/µL (87% neutrophils), C-reactive protein was 26.1 mg/dL, erythrocyte sedimentation rate was 57 mm/h, hemoglobin was 10.3 mg/dL, and albumin was 2.3 gr/dL. Vascular pathology was not detected in the lower extremity venous Doppler examination. In superficial soft tissue ultrasonography examination, diffuse thickening of skin and subcutaneous area, 3x5 cm diameter small fluid collection defined as cellulitis and abscess in the lower right leg were observed. On the second day of admission, Aeromonas hydrophila was isolated from the drainage culture of abscess. Isolated strain was resistant to penicillin, ampicillin and cefazolin, and susceptible to trimethoprim-sulfamethoxazole, ciprofloxacin and second- and third-generation cephalosporins. She was treated ciprofloxacin 400 mg IV bid and ceftriaxone 2 gr IV qd, and it was completed to 14 days. She was discharged from the hospital 16 days after admission with recovery. As noted in this case study, the cellulitis in the setting of soft tissue trauma and exposure to water and soil should alert the clinician regarding the possibility of infection with Aeromonas. [ABSTRACT FROM AUTHOR]

Agranulocytosis is a rare but life-threating side effect of antithyroid drugs such as methimazole and propylthiouracil. Female gender, age >40 years and first 3 months of antithyroid drug use are shown as risk factors for development of agranulocytosis in the literature. We reported a case of soft tissue infection occurring in a patient who has all above mentioned risk factors and developed agranulocytosis/neutropenia associated with methimazole in an attempt to notice the frequency of antithyroid drug-associated agranulocytosis, its risk factors and complications. A 73-year-old female using methimazole due to hyperthyroidism for 2.5 months admitted with fever, neutropenia and paronychia. Patient who was not followed hematologically after starting antithyroid drug was diagnosed agranulocytosis/neutropenia. During her recovery period, an ischemic necrosis in nail bed and distal phalanx of left thumb and a cellulitis on left forearm developed. She was succesfully treated with a 3-week antibiotic therapy and partial thumb amputation. [ABSTRACT FROM AUTHOR]

Although hand infections in diabetic patients are observed less frequently than foot infections, hand infections may cause severe problems, such as stiffness and loss of skin, nerve and bone persisting even after the infection resolves. Invasive soft tissue fungal infections are very rare among diabetes-related limb infections. In this report, we present a case of diabetic hand infection with invasive candidiasis. A 53-year-old female patient was admitted to our Ege University Diabetic Foot Council with necrosis and bullae at the tip of the third finger of her right hand. For surgical treatment, wound debridement and amputation were performed and a broad-spectrum antibiotic treatment was started. The tissue culture yielded Candida albicans and the patient was successfully treated with fluconazole. Inguinal flap operation was performed after antifungal (fluconazole) therapy. However, purulent discharge and ischemia with superficial necrosis of the flap developed on follow up. Thereupon, surgical debridement was performed again and antibiotic treatment was started. With the treatment of infection, flap success was achieved. Routine evaluation during follow-up of the patient revealed that eight months after the operation, the wound completely healed.

Copyright of Turkish Journal of Trauma & Emergency Surgery / Ulusal Travma ve Acil Cerrahi Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim: The soft tissue and bone tumors which are located in the upper extremity usually have a benign character. These lesions which require careful diagnosis and treatment are mostly studied retrospectively and in small series. In this study, we aimed to evaluate the relations of the tumors located in the upper extremity by age, gender, mass location, clinical and pathological diagnosis and their compliance with these diagnoses. Material and Methods: We analyzed the data of 125 patients who were operated between 2000-2011 at Inonu University School of Medicine Department of Orthopedics and Traumatology. 125 patients; 52 male (41.6%), 73 female (58.4%) were enrolled in this retrospective study. The mean age was 36,8 (7-85) years 96.8% of lesions were classified as benign and 3.2% as malign. Results: Histopathological diagnoses were ganglion cysts (28%), enchondromas (11.2%), tendon sheat giant cell tumors (5.6%) and lipomas (5.6%). We noticed that our clinical provisional diagnoses were compatible with pathological diagnoses in 60.8% of frequently seen tumors. Conclusion: The diagnosis is determined in most of upper extremity tumors by simple physical examination, and conventional radiological techniques. We must comply with the rules of tumor treatment and the mainstay of treatment for hand surgery. In benign tumors, the treatment mostly is excisional biopsy but sometimes reconstructive procedures are required. The treatment of malign tumors should be planned in a multidisciplina management. [ABSTRACT FROM AUTHOR]

Background: Foot infections in diabetic patients and frequently require a multidisciplinary approach to solving a problem. Taking the form of cellulite, soft tissue necrosis and osteomyelitis may present risks for limb amputation. Bakterolojik analysis for this reason, treatment is very important. Aim: This study aimed to determine the active micro-organisms and their antibiotic susceptibilities. Methods: A total of 63 patients with Diabetic foot infection, who were admitted to the clinics of Dicle University Hospital between October 2006 and November 2007, were included into the study. Wagner classification metod used for wound classification. Deep tissue culture was maked for bacteriological analysis. For aerobic and anaerobic culturewere rapidly sent to laboratory. Results: While 38 (60%) of patients, Wagner classification ≤2, Wagner classification ≥3 was 25 (40%) The most common isolated microorganisms are S. aureus (20 patients, 31.7%) and it was followed by Klebsiella spp. and Enterobacter cloaca. All Gr (-) isolates the most effective antibiotics against amikacin, meropenem, piperacillin-tazobactam and cefepime, respectively. They are the most resistant to the antibiotics ciprofloxacin and cefuroxime-axetil, respectively. Conclusion: An effective treatment for diabetic foot infections, determination of causative organisms and their antibiotic susceptibility is crucial to know the sensitivity shown in most of the time. [ABSTRACT FROM AUTHOR]