In the early 2000s, the 21st century, which we are living in, has been defined as the “African Century” by Thabo Mbeki, the President of South Africa. By the second half of the 21st century, Africa is expected to play a more active role in the international system and become an increasingly important actor on the global stage. The presence of global actors in Africa paved the way for regional powers to develop policies on Africa. In this context, the activities of Iran, a regional power, in Africa and foremost in North Africa particularly regarding its policy of Shi’ization, are progressing in a more assertive way than its rivals. Alongside the Persian worldview inherited from the Persian Empire, Shi'ism has significantly influenced and continues to influence the geopolitical and geo-cultural tendencies of contemporary Iran. With its politicization, Shiism has become one of the most important factors that play an important role in the creation and preservation of Iran's national identity. In this context, Iranian Shiism, which creates a different socio-cultural system vis-à-vis other neighboring civilizations, has been intertwined with Persian nationalism since the reign of Shah Ismail. It has become the main determinant of security and foreign policy in today’s Iran. In this vein, this study examines Iran's religious diplomacy and Shi’ization activities in Morocco, Tunisia, and Algeria. Understanding Iran and Iranian foreign policy, is an endeavor that goes beyond the discipline of International Relations. In other words, it is not possible to fully analyze Iran's social, political, cultural, economic, religious, sectarian structures by merely relying on the discipline and theories of international relations. Therefore, this study combines the history of Islamic sects and the international relations discipline in an interdisciplinary way, and so examines the effects of Shiism on Iran's foreign policy in the context of religious diplomacy, its ramifications in Africa, especially in Morocco-Tunisia-Algeria, by using open-source data and the developments in the region as case studies. [ABSTRACT FROM AUTHOR]