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One of the most common diseases in the whole world is obesity. Every year, 18-20 thousand new cases of obesity are recorded in Ukraine. Also, the number of obese students during their studies in institutions of higher education is rapidly increasing, for whom the first year of study is the most difficult and problematic. It is known that even under normal conditions, excessive body weight requires increased energy supply and persons with insufficient weight suffer from a lack of reserves. Therefore, the purpose of our work was to study the features of the state of neurodynamic functions and regulatory processes of the heart based on indicators of heart rate variability in female students with different body weights during the first year of study at a higher education institution. This will be important for the development of individual disease prevention measures for this category of students. The study examined full-time female students (17-18 years old) of the Faculty of Natural Geography Education and Ecology of National Pedagogical Dragomanov University, who were divided into groups according to body mass index: normal, overweight, and underweight. The study was conducted on days of high mental performance under standard conditions in six stages. An electrocardiogram was registered, rhythmograms and variation pulsometry indicators were calculated, and the functional state of the central nervous system was studied using computer methods. According to the Kruskal-Wallis and ANOVA tests, the following indicators were most sensitive to the influence of body weight: moda, moda amplitude, stress index, autonomic balance index, and heart rate. According to Spearman’s non-parametric correlation analysis, at each stage of the examination, correlations between variation characteristics of heart rate variability and indicators of the state of the central nervous system were revealed, and their nature was clarified. It was established that the nature of the correlations in the studied groups was different. Thus, it was established that the deviation of body weight from the norm affects the regulatory processes of the heart and neurodynamic functions during the first year of study. Overweight and underweight female students during the first year of study had a significantly higher intension of regulatory mechanisms compared to female students with a normal body weight, so they can be classified as a group at risk of developing psychosomatic diseases. [ABSTRACT FROM AUTHOR]

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Woźniak Kamila, Ratuszek-Sadowska Dorota, Nowacka Agnieszka, Śniegocki Maciej. Olbrzymi brodawczak splotu naczyniówkowego – opis przypadku = Giant choroid plexus papilloma – case report. Journal of Education, Health and Sport. 2016;6(8):688-694. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.61144 http://ojs.ukw.edu.pl/index.php/johs/article/view/3797 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.08.2016. Revised 25.08.2016. Accepted: 28.08.2016. Olbrzymi brodawczak splotu naczyniówkowego – opis przypadku Giant choroid plexus papilloma – case report Kamila Woźniak1, Dorota Ratuszek-Sadowska2, Agnieszka Nowacka1, Maciej Śniegocki1 1. Klinika Neurochirurgii, Neurotraumatologii i Neurochirurgii Dziecięcej, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu 2. Katedra i Klinika Rehabilitacji, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu Streszczenie Brodawczak splotu naczyniówkowego (ang. choroid plexus papilloma) to rzadki nowotwór ośrodkowego układu nerwowego, wywodzący się z nabłonka splotu naczyniówkowego układu komorowego mózgowia. W 50% przypadków rozwija się w komorze bocznej, w 40% w komorze IV i w 5% w komorze III. Guzy splotu naczyniówkowego występują przede wszystkim w 1. dekadzie życia. Guz produkuje płyn mózgowo - rdzeniowy, co przyczynia się do wodogłowia i nadciśnienia śródczaszkowego. Histologicznie zbudowany jest ze struktur brodawkowatych, utworzonych przez cylindrycznego kształtu komórki spoczywające na błonie podstawnej. Autorzy przedstawiają opis przypadku klinicznego chorej leczonej operacyjnie w Klinice Neurochirurgii, Neurotraumatologii i Neurochirurgii Dziecięcej Szpitala Uniwersyteckiego nr 1 im. dr A. Jurasza w Bydgoszczy z rozpoznanym w badaniu histopatologicznym brodawczakiem splotu naczyniówkowego. Słowa kluczowe: brodawczak splotu naczyniówkowego, nowotwór, ośrodkowy układ nerwowy, neurochirurgia. Abstract Choroid plexus papilloma is a rare cancer of the central nervous system, derived from epithelial cells of the choroid plexus of the ventricular system of the brain. In 50% of cases resolve the side chamber, and in 40% in the fourth chamber and 5% in the third ventricle. Choroid plexus tumors occur primarily in the first decade of life. The tumor produces cerebrospinal fluid, which contributes to hydrocephalus and brain edema. Histologically is built with papillary structures formed by the cylindrical shape of the cells resting on the basilar membrane. The authors present a case of clinical patient operating treated in the Department of Neurosurgery, Neurotraumatology and Pediatric Neurosurgery, Dr Antoni Jurasz University Hospital No.1 in Bydgoszcz histopathological diagnosed with choroid plexus papilloma. Key words: choroid plexus papilloma, cancer, central nervous system, neurosurgery.

The article provides an overview of modern physiological evidence to support the hypothesis on cortico&limbic sys& tem dysfunction due to the hippocampal neurogenesis impairment as a basis of the brain interhemispheric asym& metry and neurocognitive deficit after radiation exposure. The importance of the research of both evoked poten& tials and fields as a highly sensitive and informative method is emphasized. Particular attention is paid to cerebral sensor systems dysfunction as a typical effect of ionizing radiation. Changes in functioning of the central parts of sensory analyzers of different modalities as well as the violation of brain integrative information processes under the influence of small doses of ionizing radiation can be critical when determining the radiation risks of space flight. The possible long&term prospects for manned flights into space, including to Mars, given the effects identified are discussed. Potential risks to the central nervous system during space travel comprise cognitive functions impairment, including the volume of short&term memory short& ening, impaired motor functions, behavioral changes that could affect human performance and health. The remote risks for CNS are considered to be the following possible neuropsychiatric disorders: accelerated brain aging, Alzheimer's disease and other types of dementia. The new radiocerebral dose&dependent effect, when applied cog& nitive auditory evoked potentials P300 technique with a possible threshold dose of 0.05 Gy, manifesting in a form of disruption of information processing in the Wernicke's area is under discussion. In order to identify neurophys& iological biological markers of ionizing radiation further international researches with adequate dosimetry support are necessary. [ABSTRACT FROM AUTHOR]

Objective. The study was aimed at evaluating features of brain information processes and cognitive functioning in the remote period after irradiation due to the Chornobyl accident by using cognitive evoked potentials P300. Materials and Methods. The study included 128 people, 112 male Chornobyl clean&up workers in 1986-1987 with the records of radiation doses available in Clinical and Epidemiological Registry (CER) of State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine» (NRCRM) (study group) and 16 unexposed persons due to the Chornobyl disaster (control group). At the time of the survey the average age of clean&up workers (M ± SD) was (57.3 ± 5.9) years, range 44-65 years, and of unex& posed persons was (57.3 ± 6.5) years, range 44-65 years. Radiation doses were within the range 0.0002-1.23 Gy, with the arithmetic mean dose (M ± SD) of (0.2 ± 0.2) Gy and the geometric mean dose of 0.1 Gy. Results. The radiocerebral effect in the projection of the left posterior superior temporal gyrus (Wernicke's area) proportionally to the radiation dose with the possible threshold of 0.05 Gy of total irradiation was revealed, with increasing radiation dose cognitive component P300 amplitude reduces and its latency period (LP) increases, espe& cially at doses > 0.3-0.5 Gy. At doses > 0.5 Gy the functional relationship with the radiation dose for LP P300 increase in the projection of Wernicke's area (r = 0.9; p = 0.027) has been found. Conclusions. The neurophysiological features detected are fully consistent with hypotheses both on radiosensitiv& ity of human central nervous system and accelerated aging of the brain under the influence of small doses of ioniz& ing radiation, and have questioned the feasibility of long&term manned space flights (including Mars) until the development of adequate radiation hygiene standardization for space crews and invention of means for radiation protection of space flights. Further dynamic clinical and neurophysiological monitoring of individuals exposed to ionizing radiation is necessary. To identify the neurophysiological biological markers of ionizing radiation further international researches with adequate dosimetry support are needed. [ABSTRACT FROM AUTHOR]