1. [Prognostication of course and treatment of peripancreatic infiltrate in patients, suffering an acute necrotic pancreatitis].
- Author
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Susak IaM, Tkachenko OA, Malysh IR, Dirda OO, and Fedorchuk OH
- Subjects
- Adult, Ascitic Fluid drug effects, Catheters, Indwelling, Female, Hemoperfusion, Humans, Leukocytes, Mononuclear drug effects, Leukocytes, Mononuclear metabolism, Leukocytes, Mononuclear pathology, Male, Middle Aged, Pancreatitis, Acute Necrotizing complications, Pancreatitis, Acute Necrotizing mortality, Prognosis, Reactive Oxygen Species metabolism, Sepsis etiology, Sepsis mortality, Survival Analysis, Treatment Outcome, Anti-Bacterial Agents therapeutic use, Pancreatitis, Acute Necrotizing diagnosis, Pancreatitis, Acute Necrotizing therapy, Sepsis diagnosis, Sepsis therapy
- Abstract
Results of treatment of 229 patients, suffering an acute necrotic pancreatitis, complicated by peripancreatic infiltrate, were analyzed. To all the patients antibiotic prophylaxis and antibiotic therapy were conducted. In 63 (27.5%) patients the methods of extracorporal hemocorrection were applied, and in 108 (47.1%)--the "four--catheters" rule (catheter for epidural anesthesia, installment of the feeding intestinal probe further than the Treitz ligament level, the central vein catheterization, the programmed laparocentesis). In 31 (13.5%) patients there were determined the activity of mononuclear phagocytes and production of ROS (the oxygen active forms) by them in peripheral blood with objective for the purulent-septic complications prognostication. In 14 (6.1%) patients purulent--septic complications have occurred, postoperative lethality was 21.4%, general lethality--3.4%.
- Published
- 2014