1. [Modern methods of diagnosis of thrombophylic states and complex treatment of patients with thrombotic complications of severe forms of varicose disease].
- Author
-
Shchukin SP
- Subjects
- Factor V genetics, Factor V metabolism, Factor VII genetics, Factor VII metabolism, Factor XII genetics, Factor XII metabolism, Female, Fibrinogen genetics, Fibrinogen metabolism, Gene Expression, Humans, Integrin alpha2 blood, Integrin alpha2 genetics, Integrin beta3 blood, Integrin beta3 genetics, Leg blood supply, Leg pathology, Leg surgery, Male, Middle Aged, Plasminogen Activator Inhibitor 1 blood, Plasminogen Activator Inhibitor 1 genetics, Prothrombin genetics, Prothrombin metabolism, Thrombophilia genetics, Thrombophilia surgery, Thrombophilia therapy, Varicose Veins genetics, Varicose Veins surgery, Varicose Veins therapy, Venous Thrombosis genetics, Venous Thrombosis surgery, Venous Thrombosis therapy, Anticoagulants therapeutic use, Genetic Predisposition to Disease, Mutation, Thrombophilia diagnosis, Varicose Veins diagnosis, Venous Thrombosis diagnosis
- Abstract
Actual issues of surgical treatment of patients, suffering complications of severe forms of varicose disease of the lower extremities (VDLE) are discussed. The causes of unsatisfactory results of treatment in patients, suffering varicothrombophlebitis (VTHPH), the main of which--absence of the only one tactics for operative treatment and anticoagulant therapy, were analyzed. The results of patients examination, suffering thrombotic complications of severe forms of VDLE, while its recurrent course, in conjunction of VTHPH and thrombosis of deep veins of the lower extremities, using diagnostic complex "PLR genetics thrombophilia", are adduced. Differential tactics of treatment in patients, suffering severe forms of VDLE, while various localization of thrombotic process, concerning the presence of thrombophilic states, is proposed.
- Published
- 2014