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Ukraine is heading to the European scientific community, so it is relevant to study the experience of the United Kingdom of Great Britain and Northern Ireland. Curriculum curricula of universities (Birmingham City, Middlesex, Nottingham, Swansea University) are analyzed and it is proved that one of the important features of British universities, which prepare specialists for preschool education, is to develop the research competence of the future students, professional tasks based on scientific knowledge. The purpose of the article is to analyze the curriculum curricula of the universities of the United Kingdom of Great Britain and Northern Ireland and to highlight the specificities of British universities where pre-service specialists are trained. Considering the role of curriculum content in the welfare of preschoolers, we note that the British National Preschool Education Program defines the requirements for the protection and well-being of preschoolers, and in the curricula of pre-baccalaureate baccalaureate studies, the students are taught modules that teach students children, legislation to support them, protection issues, the welfare of children, the impact of a supportive environment on children's learning; are aware of the role of early childhood professionals in the protection of children, their responsibilities for safety in care, upbringing and training. We believe that it is very important that students consider special educational needs and disabilities in modules, as future professionals of pre-school education will need this in the process of fulfilling their professional responsibilities in the workplace. However, it should be noted that not all universities meet the requirements of the national preschool education program for the protection of preschoolers. Based on the analysis of the content of the curriculum for the preparation of bachelors of pre-school education at the universities of the United Kingdom of Great Britain and Northern Ireland, we can conclude that the specific content of modules with a research orientation contributes to the formation of research competence, the solution of professional tasks, based on scientific knowledge and scientific knowledge, about teacher-teacher training that we consider to be one of the progressive ideas of pre-school teacher training that needs to be implemented in the process conducting educational reforms or the educational process of the Ukrainian higher education institution.

The specificities of the preparation of future pre-school teachers in higher education institutions in the United Kingdom and of Northern Ireland are analyzed for pre-school education in four areas (literacy, mathematics, understanding of the world, art and design). The workload of pre-service teacher training courses at different universities in the UK and Northern Ireland has been characterized and their similar features identified (pre-block blockchain construction; few or no exams, teaching methods, teaching methods for each course, crediting up to a total of 1 credit of approximately 10 hours, use of a virtual learning environment and different: in the number of credits per module (in Mi each module is divided into thirty credits, and at the universities of Swansea, Birmingham City and Nottingham Trent - 20 and 40 credits respectively; in the number of credits envisaged for study for 3 years (at the University of Nottingham Trent - 280 credits; 3600 credits for the entire period of study) in the assessment methods provided in the curriculum (at Swansea and Middlesex Universities, they are numerous, creative and extremely diverse; at the University of Birmingham City more attention is paid to the implementation of scientific work, and at the University of Nottingham Trent at each course the effectiveness of the study is determined by the scientific work). Comparing the curricula modules of pre-university bachelors' training for pre-school specialist training, we also identify the following common features (some modules represent early education curricula, as well as a key step in the first section of the British National Preschool Program; individual pre-service teacher modules education to the learning and development of children through play, others - in particular, with cognitive, social, physical, speech directions early education of preschool children; distinctive features (module introducing students to work in partnership at three universities is provided in one missing; modules whose names are similar and functions performed by students of different higher education institutions in the course of studying the content of the modules differ); distinctive features are also identified for individual universities (at Birmingham City University students can master international programs, at Swansea University well posed digital issues, at Middlesex one module provides a deep mastery of educational issues to change it for the better).

In this paper, we propose the technique for computing the scheme of holographic recording on the photopolymer of photonic structures, which create various discrete non-diffracting beams. We study how a number of laser beams, scheme geometry and relative phase shifts between laser beams impact the resultant transverse intensity and phase distribution in the interference structure. Moreover, we numerically model such structures as striped, triangular, square and hexagonal structures, specifically kagome and honeycomb pattern. By applying specific analysis of the beam phase shifts, we simulate vortex structures. These structures are characterized by point and line phase dislocations. We demonstrate experimental results of structures recording and show that adding the central laser beam to the recording scheme makes it possible to obtain a number of 3D structures. [ABSTRACT FROM AUTHOR]

Experiments for optimization of the clfA gene expression in E. coli XLI-Blue cells were conducted. The reducing of the strain efficiency and the elimination of the plasmid during the cultivation of a producer have been shown. Several methods for raising the amount of plasmid-containing cells and increasing the yield of recombinant protein were proposed. Bacterial growth medium was selected to make this process more efficient. In such conditions after IPTG induction of the recombinant cells we have received high level of a soluble protein (about 30% of total cellular protein). The recombinant protein containing the His tag on N-terminus was purified on IDA-Sepharose column with high yield.