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The invention relates to a system for obtaining biomechanical parameters of ocular tissue (C), the system comprising: - an air-puff module (200) configured to deliver at least one air-puff stimulus onto the ocular tissue; - an imaging device (100, 100') operatively coupled to the air-puff module (200); characterised in that - the air-puff module comprises a transparent window (PW) at its front thereof, the transparent window having a transparent through hole (OD) for delivering the at least one air-puff stimulus, the hole configured to be aligned with an optical axis of the imaging device, such that the air-puff stimulus delivered onto the ocular tissue can be centred on an apex of the ocular tissue and can be made collinear with the optical axis of the imaging device, the transparent window (PW) and its transparent through hole further allowing continuity of imaging of the ocular surface; - the imaging device (100, 100') being configured to capture the three-dimensional coordinates of a plurality of points distributed on a surface of the ocular tissue, captured in groups of at least two simultaneous points; the system further comprising: - means for selecting and changing the location and distribution of the plurality of captured points on a surface of the ocular tissue; - processing means configured to process the plurality of points provided by the imaging device for obtaining biomechanical parameters of the ocular tissue. The invention also relates to a method for obtaining biomechanical parameters of ocular tissue, especially, corneal biomechanical parameters., Consejo Superior de Investigaciones Científicas (CSIC), Instytut Chemii Fizycznej, The University of Liverpool, A1 Solicitud de patente con informe sobre el estado de la técnica

The present disclosure relates to a method and a system for biomechanically characterising ocular tissue (C) through deformation of the ocular tissue. The method comprises: - generating an acoustic stimulus for delivery onto the ocular tissue in a collinear manner with an axis of a measuring device, for producing vibration of the ocular tissue; - measuring ocular tissue displacement with the measuring device at a plurality of locations of the ocular tissue; - obtaining at least a biomechanical parameter by processing the ocular tissue displacements at the plurality of locations. The disclosure also relates to a method and a system for screening biomechanical abnormality of ocular tissue (C)., National University of Ireland Galway, Consejo Superior de Investigaciones Científicas, University of Liverpool, A1 Solicitud de patente con informe sobre el estado de la técnica

ARVO Annual Meeting Abstract , June 2020

PIE BiOS, San Francisco, California, United States, 17 Marzo 2020. -- SPIE Proceedings Vol. 11218: Ophthalmic Technologies XXX . -- https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11218/2546050/Customized-swept-source-optical-coherence-tomography-system-for-air-puff/10.1117/12.2546050.full?SSO=1

VioBioLabVisual Optics and Biophotonics lab, Vancouver Convention Centre, Vancouver, B.C., April 28 – May 2 (2019)

Vancouver Convention Centre, Vancouver, B.C., April 28 – May 2 (2019)

The invention refers toa system (lOO) for obtaining biomechauical properties of ocular tissue, the system comprising: -an air-puff generator (lO) configured to generate a stepped-frequency train of air-pnff pulses of dífferent frequencies for delivery onto the ocular tissue; -an imaging device (20) operatively coupled to the air-pnff generator, the imaging device being configured to capture a plurality of axial positions of a region of the ocular tissue; -processing means (30) configured to: -process the plurality of axial positions provided by the imaging device for obtaining displacement and velocity of the region of the ocular tissue at the dífferent frequencies; and to -carry out frequency domain analysis of the obtained displacements and velocities of the region of the ocular tissue at the dífferent frequencies to at least derive a mechauical resonance frequency of the ocular tissue; and to -perform inverse calculation and obtain biomechanical parameters and intraocular pressure of the ocular tissue using the displacement, velocity and mechanical resonance frequency as inputs in a Fine-Element-Model based calculation. The invention also relates toa method for obtaining biomechauical parameters of ocular tissue., Consejo Superior de Investigaciones Científicas (España), Wellman Center for photomedicine, A1 Solicitud de patente con informe sobre el estado de la técnica

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018., Support NIH Grant 228599 P41, Marie Curie Actions

World Meeting in Visual and Physiological Optics, Wroclaw, Poland, 25-27 August 2014

Orlando, United States, 4–8 May 2014, To compare the spherical aberration of cynomolgus monkey lenses measured with a laser ray tracing (LRT) system and the spherical aberration estimated from numerical ray-trace through a model of the lens with the measured lens shape and a reconstructed gradient refractive index (GRIN).

Spanish Government Grant FIS2011- 25637 to SM; European Research Council ERC-AdG-294099 to SM; CSIC JAEPre Program to JB; CSIC i-LINK+ 2012, i-LINK+0609 to SM.

ARVO Annual Meeting 2013, Washington State Convention Center, May 5-9, 2013

ARVO Annual Meeting 2013, Washington State Convention Center, May 5-9, 2013, Spanish Government Grant FIS2011-25637; European Research Council ERC2011 AdG-294099; EU Marie Curie FP7-PEOPLE-2010-ITN 264605; CSIC JAE-Program; Unidad Asociada IO-CSIC/FJD